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Launch HN: Wyndly (YC W21) – Allergy relief through at-home oral drops

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Re: Launch HN: Wyndly (YC W21) – Allergy relief through at-home oral drops

#101

Post by ta988 »

yumraj wrote: post #92
djyaz1200 wrote: post #10

Congrats on your launch! This sounds really promising! How do you deal with the risk of severe reactions? Is that risk diminished with drops instead of shots? I'm undergoing shot therapy now and had a life threatening anaphylactic reaction to a shot just a couple months ago. I'm concerned if I had been by myself at home I may have died? I was at the doctors office but they still called 911 for "backup" because I got…

Do you take an antihistamine before your shots? If not you may want to do that, that severely reduces the risk of a reaction.

Wouldn't that reduce the benefits of the shot as well?

Re: Launch HN: Wyndly (YC W21) – Allergy relief through at-home oral drops

#102

Post by ahstilde »

borski wrote: post #100

Genuine question: there are already many others doing this, including online. For example: https://myallergydrops.com/ https://www.allergyeasy.com/ How do you folks differentiate?

When we started Wyndly, we didn't find anyone doing the patient-focused care that we would want if we were patients. Our patients love our treatment and our patient experience, and that's what's most important.

We're happy to see that other people are trying to make oral allergy drops more popular! Allergy drop immunotherapy is easier and more convenient than the standard allergy shots.

I can't speak to these specific companies -- I am not familiar with them and their business models.

Re: Launch HN: Wyndly (YC W21) – Allergy relief through at-home oral drops

#103

Post by whymauri »

dlevine wrote: post #89
whymauri wrote: post #41

Earlier quoted context omitted.

How effective is this against eczema? Without proper insurance, this is a better deal than medications like Dupixent, right?

I recently started allergy shots, and am also on Dupixent. I asked my allergist about this when I started shots. He said that it might help with the Eczema, but nothing is guaranteed. There is at least anecdotal evidence indicating that allergy shots might be helpful for Eczema. https://acaai.org/news/your-severe-eczema-may-best-be-treate... If you don't have insurance, Dupixent is like $2000 per month. Not sure whet…

I'm glad to hear about your Dupixent journey! We're looking forward to getting some. Thanks for the insight on allergy drops.

Re: Launch HN: Wyndly (YC W21) – Allergy relief through at-home oral drops

#104

Post by refurb »

Shoop wrote: post #15

I would recommend toning back some of the emotional language in your treatment comparison table -- things like "confusing terminology", "Busy staff with no time to help", and "Unhelpful Google searches". Your value prop of convenience of no shots is super obvious to me but the biased comparison table is a turn-off. It would give me a lot more confidence if the language in the table were more scientific and clinical.…

As someone who works in healthcare I’d tone down the language before the FDA sends them a warning letter.

Using terms like “learn how to beat your allergies in 60 seconds” and “leave your allergies behind” are efficacy claims that the FDA takes very seriously. Right now it gives the impression that the company guarantees I’ll beat my allergies and I can do it in 60 seconds, both of which I doubt are true.

Plenty of companies have been cited for less bombastic claims than those.

Re: Launch HN: Wyndly (YC W21) – Allergy relief through at-home oral drops

#105

Post by yumraj »

ta988 wrote: post #101
yumraj wrote: post #92

Earlier quoted context omitted.

Do you take an antihistamine before your shots? If not you may want to do that, that severely reduces the risk of a reaction.

Wouldn't that reduce the benefits of the shot as well?

Disclaimer: I’m not a doctor, but speaking from personal experience.

I don’t believe so. At least it’s recommended by our allergy doctor before the shots and I’ve read it on other allergy doctors’ websites also.

In fact this link suggests that it improves the effectiveness[0]

[0] https://acaai.org/resources/connect/ask-allergist/antihistam...

Re: Launch HN: Wyndly (YC W21) – Allergy relief through at-home oral drops

#106

Post by ahstilde »

Shoop wrote: post #21
ahstilde wrote: post #9

Earlier quoted context omitted.

Thank you for the feedback! On total cost: We charge $99/mo. It's hard to give a total cost without knowing more about each person's specific allergy triggers and how well immunotherapy takes for them. Generally, we expect patients to be with us for up 5 years. On how long treatment lasts: I spoke to this in the total cost section, but it's hard to make a blanket statement. On our at-home allergy test: We use a CLIA-…

Is IgE present in the bloodstream if I have not been exposed to the allergen recently? E.g. will I show as positive for a pet dander allergy if I have not been around pets for many years?

Yes, the test can detect allergies even if you haven't been exposed for some time.

However, we can use any allergy test you have -- a QuestLabs ImmunoCap or a traditional mulit-needle scratch test.

Re: Launch HN: Wyndly (YC W21) – Allergy relief through at-home oral drops

#107

Post by ahstilde »

whymauri wrote: post #41
ahstilde wrote: post #9

Earlier quoted context omitted.

Thank you for the feedback! On total cost: We charge $99/mo. It's hard to give a total cost without knowing more about each person's specific allergy triggers and how well immunotherapy takes for them. Generally, we expect patients to be with us for up 5 years. On how long treatment lasts: I spoke to this in the total cost section, but it's hard to make a blanket statement. On our at-home allergy test: We use a CLIA-…

How effective is this against eczema? Without proper insurance, this is a better deal than medications like Dupixent, right?

We do not suggest allergy drop immunotherapy for eczema.

Re: Launch HN: Wyndly (YC W21) – Allergy relief through at-home oral drops

#108

Post by ahstilde »

Pfhreak wrote: post #50

My allergies are seasonal and pet related, and they provide me some nuisance every year but aren't generally debilitating. That said, itchy eyes and a nasal drip are annoying and there's probably some amount I'd pay to just not have to deal with them. I think my worry is that I'd start something like this and experience the same low grade symptoms (e.g., a treatment like this might improve my symptoms, but only take…

Allergy drop immunotherapy (SLIT) can help allergy sufferers with both sever and mild symptoms have significant reduction in their symptoms -- or, in your language, it helps people with low-grade allergies too. However, if an over-the-counter allergy med is all you need, then maybe that's the right treatment for you.

Our treatment is for people who don't want to worry about taking an allergy medication during allergy season at all.

Re: Launch HN: Wyndly (YC W21) – Allergy relief through at-home oral drops

#109

Post by ahstilde »

ssully wrote: post #55

Have you looked into doing drops for pets? Both of my dogs get bad seasonal allergies. Their paws get so itchy they will lick the fur off unless we get them help. The allergies start up in July and persist until the first frost of the season (late October or November). We have done both shots and medications from our vet that help alleviate the symptoms, but they don't have any long term solutions. We've moved while…

Interesting! Maybe that's an expansion opportunity after we've treated all the humans.

Re: Launch HN: Wyndly (YC W21) – Allergy relief through at-home oral drops

#110

Post by ahstilde »

qorrect wrote: post #73
ahstilde wrote: post #44

Earlier quoted context omitted.

Sorry about that! I'll try to be more clear: Patients see improvement in symptoms after 6 months, with some patients reporting improvement as soon as 6 weeks. If patients stays on drops for 5 years, they can expect significant decrease in allergy symptoms for decades, even once they have stopped taking a daily allergy drop. If the patient stops taking their allergy drops, they will still see a reduction of their alle…

When do the drops reach their max potency ?

Our protocol is proprietary, but in general the drops reach maintenance dosage between 3 to 9 months.
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