Python feels noticeably slower than Node.js, particularly when running scripts with large amounts of imports. I now pretty much always use JavaScript for, well, scripting. Not sure why Python and Ruby are considered go-tos there.
Opening / reading / writing files, parsing args, making HTTP requests, etc. which are extremely common scripting operations are easier with Python, and the end result tends to be much more succinct thanks to its syntax (this applies to all Python code compared to JavaScript, but I'd argue it's especially valuable in shorter scripts).