I wonder if radiation will become an issue at some point. It is being irradiated all the time, doesn’t it also start to leak inside? Can that be an issue in the future for inhabitable objects in space?
On the ground, most radiation 'leaks' are mostly chemical contamination problems.
In space the volume of free material, and the pressure gradient should prevent anything outside coming in. Except perhaps on the exposed surfaces of the airlocks/docking adapters.
Come types of particle radiation might cause transmutation/activiation of the hull material - that could be a concern. I doubt it's major issue.