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SARS-CoV-2 501Y.V2 escapes neutralization by South African COVID-19 donor plasma

biorxiv.org

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Re: SARS-CoV-2 501Y.V2 escapes neutralization by South African COVID-19 donor plasma

#61

Post by Loughla »

mc32 wrote: post #44
Loughla wrote: post #30

Earlier quoted context omitted.

I think you lost me. How can we have an unfettered economy, not limited by lockdowns AND contain mutations regionally? These two statements you have made seem to be at odds with one another. Or am I overthinking/underthinking this?

One affects the global economy, the alternative affects a local economy, for example.

The local economy is the global economy. Things I make here get shipped there, unless my business is shut down because of local mandates. Then nothing gets shipped over there.

I think you're oversimplifying and I can't figure out how to explain myself.

Re: SARS-CoV-2 501Y.V2 escapes neutralization by South African COVID-19 donor plasma

#62

Post by dionian »

dougmwne wrote: post #51
beamatronic wrote: post #37

Earlier quoted context omitted.

Or you could just wear a mask and social distance and not congregate indoors with random strangers for long periods of time

These are necessarily temporary measures. Life cannot go on forever with these restrictions in place. Either medical science will find a way to limit the danger or people will adapt to their new, more dangerous world. I am not an anti-masker, but asking for permanent social distancing is not realistic.

I think voluntary mask wearing becoming a new norm is fine with me

Re: SARS-CoV-2 501Y.V2 escapes neutralization by South African COVID-19 donor plasma

#63

Post by icedchai »

beamatronic wrote: post #33
mc32 wrote: post #11

If we can expect more surprises like this, movement will have to be curtailed till we’re sure we have things under control (like SARS). We can’t have the whole world economy in lockdown because a new strain spread because prior immunization is ineffective against the variant.

If you COORDINATE lockdowns and everyone works in harmony they can be very short. You could even schedule them in advance.

Getting everyone to work in harmony is basically impossible. If a politician goes on the news and say you need to stay home for 2 weeks starting next Friday, what do you thinks going to happen? Mass panic buying and looting? People refusing to do it because it's a conspiracy? Mass protest events encouraging super spreading? By the time this is all over, 2 weeks has passed...

Re: SARS-CoV-2 501Y.V2 escapes neutralization by South African COVID-19 donor plasma

#64

Post by nicpottier »

CWuestefeld wrote: post #56

This is how the FDA's refusal to balance up-side risk is going to damage all of us. They're only interested in minimizing the risk from a treatment itself, and pay little to no attention to the risk from not having any treatment. It's been a full year since the first vaccines were formulated, and it took the FDA 11 months to give the OK. That was a large streamlining of their normal processes, but not a meaningful ba…

This is an interesting take for sure that I hadn't heard before. Do you have more information on how they could have accelerated things?

If feels like the risk of shipping a vaccine that later is found to have adverse side effects would be so dangerous to the trust of the FDA that it would be really dangerous. Think of the shattered trust on both the FDA side and on vaccines in general, feels like maybe that would be too big a risk to take.

Re: SARS-CoV-2 501Y.V2 escapes neutralization by South African COVID-19 donor plasma

#65

Post by xeromal »

dionian wrote: post #62
dougmwne wrote: post #51

Earlier quoted context omitted.

These are necessarily temporary measures. Life cannot go on forever with these restrictions in place. Either medical science will find a way to limit the danger or people will adapt to their new, more dangerous world. I am not an anti-masker, but asking for permanent social distancing is not realistic.

I think voluntary mask wearing becoming a new norm is fine with me

Are you speaking for literally every human?

Re: SARS-CoV-2 501Y.V2 escapes neutralization by South African COVID-19 donor plasma

#67

Post by mc32 »

Loughla wrote: post #61
mc32 wrote: post #44

Earlier quoted context omitted.

One affects the global economy, the alternative affects a local economy, for example.

The local economy is the global economy. Things I make here get shipped there, unless my business is shut down because of local mandates. Then nothing gets shipped over there. I think you're oversimplifying and I can't figure out how to explain myself.

Let’s say you produce wine in France. France has a new variant. We shut France down. You’re French and live there. You’re affected. I’m in Mauritania, I keep on working unaffected by your shutdown.

You’re saying it’s preferable to have your economy, my economy and everyone else’s economy because... it’s better for you if we all get shut down?

Re: SARS-CoV-2 501Y.V2 escapes neutralization by South African COVID-19 donor plasma

#70

Post by kube-system »

CWuestefeld wrote: post #56

This is how the FDA's refusal to balance up-side risk is going to damage all of us. They're only interested in minimizing the risk from a treatment itself, and pay little to no attention to the risk from not having any treatment. It's been a full year since the first vaccines were formulated, and it took the FDA 11 months to give the OK. That was a large streamlining of their normal processes, but not a meaningful ba…

The FDA is slow? Compared to what? They approved the first vaccine 3 days after the NHS.

If your window of success vs. failure is very small, you simply have to test before you push to prod. Especially when using a technique with a long history of failed attempts.

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