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Why cancer cells waste so much energy

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Re: Why cancer cells waste so much energy

#141
I suggest that anyone interested in this topic research Johanna Budwig and her Budwig Protocol. She was a world expert on essential fats as well as a physicist. Her work directly followed on that of Otto Warburg, and it is said she cured many many people of Cancer. Having tried her "Budwig Protocol" myself at a time when my energy levels were so low that I had to quit my job and focus only on recovering my health, I can attest that it truly works for delivering more oxygen and thus energy and vitality to one's cells. Today I am healthy and feel much better than I did 5 years ago.

Re: Why cancer cells waste so much energy

#142

Earlier quoted context omitted.

" Tripping Over The Truth ," seconded.

I’m listening to his other books now, Ketones. There’s also Emperor of All Maladies (and his other book Genes) from another author that may be of interest.

> There’s also Emperor of All Maladies (and his other book Genes) from another author that may be of interest.

Author name's Siddhartha Mukherjee. Great book, focused more on history of oncology than the biology of cancer though.

Re: Why cancer cells waste so much energy

#143

Earlier quoted context omitted.

Since you were a cancer researcher in a previous life, may I ask you a question I thought of commenting on another's comment? If cancer cells have high metabolic requirements, couldn't you attack them by: 1. lowering the caloric intake of the patient 2. Making the glucose the patient intakes mildly radioactive, say with a beta or an alpha emitter [1]. As the patient is strictly kept on a low caloric diet, the radioac…

Great questions. 1. We do attempt to attack cancers by reducing their available energy. That's why, at one point, a major field of research in cancer therapeutics was interfering with angiogenesis, because cancers will secrete messengers that help grow them dedicated (if crappy, low-quality) blood vessels. The issue with "starving" them more starkly is that they're very good at getting a share (e.g., forcing the body…

"I hope my answer was actually useful in providing some biological context? "

Yes, it was!

"These are below detection in any practical clinical way, and we don't want to treat them because they're ridiculously common - your immune system wipes them up. If we tried to detect and treat them all, we'd kill everyone with side effects long before we prevented a fatal cancer."

I suppose it would help, if this would be more common knowledge. That cancer cells are very common and nothing to be afraid of. Just that when things go very wrong, it becomes a problem. And that is mainly, when the immune system fails?

So I suspect the stress for the fear of getting cancer, might in some people lead to actual cancer, by lowering their immune system.

Could you agree to such a statement, or do you think it is far off?

Re: Why cancer cells waste so much energy

#144

Earlier quoted context omitted.

Since you were a cancer researcher in a previous life, may I ask you a question I thought of commenting on another's comment? If cancer cells have high metabolic requirements, couldn't you attack them by: 1. lowering the caloric intake of the patient 2. Making the glucose the patient intakes mildly radioactive, say with a beta or an alpha emitter [1]. As the patient is strictly kept on a low caloric diet, the radioac…

Great questions. 1. We do attempt to attack cancers by reducing their available energy. That's why, at one point, a major field of research in cancer therapeutics was interfering with angiogenesis, because cancers will secrete messengers that help grow them dedicated (if crappy, low-quality) blood vessels. The issue with "starving" them more starkly is that they're very good at getting a share (e.g., forcing the body…

I appreciate your comprehensive answer, it's very helpful.

Question:

> "you'll starve, or poison, the brain long before you manage to starve out a cancer. (Yes, Ketone bodies are a thing, but that happens alongside your body mobilizing everything it can to feed the brain, not instead of.)"

Layman here, but my understanding is that depriving the body of the ability to replenish glycogen stores that are normally used for energy forces the body to metabolize fat in order to produce ketones, which in a ketogenic state, the brain is entirely fine utilizing as a primary energy source. Thus, if in a ketogenic state (or on a strict ketogenic diet), the body isn't being starved, just consuming stored energy reserves.

Am I oversimplifying the concept?

Re: Why cancer cells waste so much energy

#145
post #22

I've been thinking and came to the conclusion that cancer might be a way of the body to get rid of excess sugar and maybe other toxins. Many cancers seem to respond well when ppl go keto for example

In this thread: Web engineers turned Cancer specialists.

Re: Why cancer cells waste so much energy

#146
post #26

Earlier quoted context omitted.

This didn't work for Steve Jobs

Jobs also had pancreatic cancer. It's just about the worst cancer you can get. Over 95% mortality rate. I don't think he did himself any favors by eschewing medical treatment in favor of alternative "medicine", but the harsh reality is that he was doomed no matter what.

> Jobs also had pancreatic cancer. It's just about the worst cancer you can get. Over 95% mortality rate.

Jobs had GEP-NET cancer, which have 5 years OSR of 70% at stage IV. It's a slow growing cancer, very survivable and even surgically curable in early stage.

The fast, almost always fatal is the pancreatic adenocarcinoma.

Also, the mortality rate of a cancer is a function of many variables (stage at the time of diagnosis, tumor differentiation, tumor location, etc.). A number like 95% doesn't make any sense without a lot of context.

Re: Why cancer cells waste so much energy

#147

Earlier quoted context omitted.

Since you were a cancer researcher in a previous life, may I ask you a question I thought of commenting on another's comment? If cancer cells have high metabolic requirements, couldn't you attack them by: 1. lowering the caloric intake of the patient 2. Making the glucose the patient intakes mildly radioactive, say with a beta or an alpha emitter [1]. As the patient is strictly kept on a low caloric diet, the radioac…

There is a very interesting book around the metabolic route for treating cancer. It's called "Starving cancer" by Jane McLelland. It talks about using over the counter drugs and supplements that have been studied for their metabolic blocking properties for cancer, as well as changing the diet to reduce as much as possible the nutrients that cancer craves the most according to their metabolic phenotype. Most of the ti…

What is "cancer industry"?

Re: Why cancer cells waste so much energy

#148

Earlier quoted context omitted.

I don't agree with trusting YouTube blindly. I trust my friends and colleagues that have cured their cancer better. Also note that chlorine dioxide is not sodium hypoclorite. It's like comparing salt (which also contains chlorine) with sugar.

>chlorine dioxide is not sodium hypoclorite I wasn't sure what to make of what you said until you dropped this common fallacy used by MMS cultists. All forms of oxidising bleach (chlorine gas, hypochlorite solution, chlorine dioxide, hydrogen peroxide, sodium perborate, etc) take effect by taking electrons from other matter. These reactions are able to "bleach" because pigments are often complex organic molecules whi…

> [...] which has no medical basis whatsoever.

I'm not a doctor, but there seems to be some medical basis in some pathologies. If you are a doctor or scientist perhaps your input would be greatly appreciated in the following papers:

In vivo evaluation of the antiviral effect of ClO2 in chicken embryos inoculated with avian infectious bronchitis coronavirus https://www.biorxiv.org/content/10.1101/2020.10.13.336768v1

Subchronic toxicity of chlorine dioxide and related compounds in drinking water in the nonhuman primate https://pubmed.ncbi.nlm.nih.gov/7151767/

Mechanistic aspects of ingested chlorine dioxide on thyroid function: impact of oxidants on iodide metabolism https://pubmed.ncbi.nlm.nih.gov/3816729/

Efficacy and Safety Evaluation of a Chlorine Dioxide Solution https://pubmed.ncbi.nlm.nih.gov/28327506/

Also, CDS is not MMS.

Re: Why cancer cells waste so much energy

#149
post #129

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If something is flagged by YouTube, it must be a really bad idea. Chlorine isn’t too bad in terms of toxicity, or it wouldn’t be added to drinking water and freely sold for all sorts of purposes. But there’s absolutely no reason to ingest it (or any other route of administration). I guess it’s exactly because of it’s ubiquity that those of a conspiratorial mindset like it so much: it fits with the idea that there are…

I don't think you should get health advice from banned YouTube videos. In fact for the average layperson, figuring out what's good information and what's bad information on YouTube or the internet in general is probably beyond their abilities. I know my dear mother, who I love, can't do it. I like to think I can, but I'm the least qualified person to judge that. I'm also not average. But I want to point out that one…

I think it really depends on your statistical survival rate. If you're almost guaranteed to die, there's less of a concern in using yourself as a test subject.

Re: Why cancer cells waste so much energy

#150
I take a daily dose of NMN to boost NAD+ levels. I was aware that NAD+ could accelerate cancer growth, but does anyone know if there's any evidence to suggest NAD+ could cause cancer or at least increase the likelihood of developing it?

From what I understand most experts seem to think it's probably safe and will extend health & life span, but the cancer risk is something that concerned me when I started. Surely if healthspan was as easy as just raising NAD+ levels the body would have already evolved this trait?

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