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Moderna is announcing three new vaccine programs

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Re: Moderna is announcing three new vaccine programs

#21
post #13
post #9

Earlier quoted context omitted.

>amateur opinion based on mainstream broad understanding I don’t think experts are reading tea leaves and it’s pretty wild to claim that. There are literally billions of dollars at stake. To bring it bag to software, that’s like me claiming I think machine learning people are just using fancy excel formulas.

I mean... it's a lot of excel formulas, but still basically excel formulas!

[deleted]

Re: Moderna is announcing three new vaccine programs

#22

Would it be easier to cover more flu strains with an mRNA vaccine? Could we shove like 100 in there?

Sure, but who do you know that’s willing to get 100 flu shots in a year?

You can put more than one drug in a single shot. The MMR vaccine contains Mumpsvax, Attenuvax, and Meruvax to fight the mumps, measles, and rubella, respectively

Re: Moderna is announcing three new vaccine programs

#23

Would it be easier to cover more flu strains with an mRNA vaccine? Could we shove like 100 in there?

Sure, but who do you know that’s willing to get 100 flu shots in a year?

I think OP means one shot with a lot of strains in it.

Re: Moderna is announcing three new vaccine programs

#24

Would it be easier to cover more flu strains with an mRNA vaccine? Could we shove like 100 in there?

Sure, but who do you know that’s willing to get 100 flu shots in a year?

Not sure if this is a flippant response, but I believe the parent post meant 100 strains in one injection.

Re: Moderna is announcing three new vaccine programs

#25

Would it be easier to cover more flu strains with an mRNA vaccine? Could we shove like 100 in there?

There is a Netflix documentary called Pandemic about couple that is trying to eradicate flu. They found vaccine that works on all flu viruses but it takes 6 shots to work. That’s not practical at all therefore it’s not on the market yet.

Re: Moderna is announcing three new vaccine programs

#26
post #14

Earlier quoted context omitted.

Yeah I agree - so much of the original downlplaying of Covid was along the lines of "Well, the flu kills 50,000 people per year and we don't take extraordinary measures" which is an insane line of thought for multiple reasons but not least because we just write off 50,000+ people per year without much of a stink.

Don't they already have flu vaccines. I thought the issue was that they changed so rapidly the vaccines can't keep up?

Yeah, it's very difficult to predict which are going to be the dominant strains so they take a best guess, include the several candidates that they expect to be most virulent that season and ship that as the "flu vaccine" that season.

The hope is that with a much faster time from approval -> production, in theory we could reassess in October / December / February and vaccinate against the most virulent strains that are actually showing up in populations. There are reports that Moderna had a vaccine developed in two days once they received the sequence from researchers. If they or similar companies received "platform" approval to ship new vaccines with abbreviated testing, it could dramatically change how we vaccinate for the flu.

Re: Moderna is announcing three new vaccine programs

#28

I am curious how a trial for the HIV vaccine will proceed in a world where PrEP is available.

PrEP might be available, but there are still countries where it is not easily accessible, and where HIV is still spreading.

https://www.who.int/news-room/spotlight/why-the-hiv-epidemic...

Re: Moderna is announcing three new vaccine programs

#29
post #3

Really good news! Hopefully these get approved relatively quickly. I'm most excited about the seasonal flu vaccine. That could be a major game changer.

Why? Does elderberry not work for you?

Some anecdata: I had the flu NUMEROUS times as a child/young adult. I know what the flu feels like. A couple of years ago, I got the flu (no, I didn't go to the doctor because I knew it was 'just' the flu). I was feeling crummy one day, and the next I was curled up in bed, unable to move, fever with body aches, and slept most of that day. My wife told me about elderberry and gave me 4 or 5 spoonfuls of an elderberry tincture throughout the day. The next day, I was shoveling compost in the yard.

https://pubmed.ncbi.nlm.nih.gov/15080016/

Re: Moderna is announcing three new vaccine programs

#30

I am curious how a trial for the HIV vaccine will proceed in a world where PrEP is available.

There's a lot of places in the world that have not approved PrEP. And just like a birth control pill, it has to be taken daily -- and that is something that is hard for a lot of people to do consistently.

Even in the West, isn't it really expensive?

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