I hope this to be the case, but the large businesses that own large chunks of city real estate will push hard to get people back in and paying rent.
Frankly, I hope some areas are abandoned or made radically cheaper, and are reclaimed by impoverished artists and other bohemians. This process has happened in the past and has enriched many old cities. By the same token, I'd also love to see blue-collar workers able to move back into cities where they work, but where they're currently priced out of house ownership.
We might see a boom in commuting two or three days per week, and a growth in clusters of more localised communities, more like villages than cities. They might encircle a city made of a mix of business meeting places (office blocks) and the more bohemian/blue-collar pockets I mention.
At least, that's what I'd like to see. I don't know if it's a prediction as such.
I'd also like to see desk- and office-rental businesses openly embrace this and explicitly move away from current models that encourage the corporate sterility seen in many modern cities, and towards an enriched, happier working environment.
I can hope!