Live data from Hacker News

Israeli startup claims Covid-19 likely originated in a lab, willing to bet on it

rootclaim.com

251–260 of 372 posts

Re: Israeli startup claims Covid-19 likely originated in a lab, willing to bet on it

#251

Earlier quoted context omitted.

Exactly, like under the 'WIV lab procedures' section it states: Probabilistic Estimates: Labs with lax security and procedures are conservatively estimated as 2x more likely to produce a lab escape. However, since the reports are not very reliable, this is reduced to 1.5x. There's no explanation or methodology presented as to how they derive these probabilities based on articles they found in the news and most of the…

The nice thing about Bayesian analysis is that you have to make your priors explicit. That’s what this is, a prior. It doesn’t have to have a derivation; it can just be a guess. The important thing is that you’re writing your guess down so everyone can see it. You can then also do a sensitivity analysis to figure out how much your conclusions change if you modify your priors. So if you, the reader, think the priors a…

The major issue here is that the sensitization of priors can be a marketing ploy.

It's very easy to "make guesses" that present your conclusion, throw in a paltry amount of money, then make bank off the publicity.

This possibility poisons the well for the entire process. If they can make money off this even if they are completely off-base, then it's not rational to build up the trust necessary in their process to engage with their model.

Re: Israeli startup claims Covid-19 likely originated in a lab, willing to bet on it

#252
post #247

Peter Daszak, the president of the EcoHealth Alliance researching the origins of pandemics, pointed out in April that nearly 3% of the population in China's rural farming regions near wild animals already had antibodies to coronaviruses similar to SARS. "We're finding 1 to 7 million people exposed to these viruses every year in Southeast Asia; that's the pathway. It's just so obvious to all of us working in the field…

Yeah, I initially thought having a big bio lab in the city where the pandemic started, in a country with a history of managing security in their bio labs poorly, in a lab known for studying sars like coronaviruses, including gain of function research to better bind to human ace2 receptors was just too many coincidences. You have to admit it's believable. But then when you realize how many people in rural China have b…

[deleted]

Re: Israeli startup claims Covid-19 likely originated in a lab, willing to bet on it

#253
post #247

Earlier quoted context omitted.

Yeah, I initially thought having a big bio lab in the city where the pandemic started, in a country with a history of managing security in their bio labs poorly, in a lab known for studying sars like coronaviruses, including gain of function research to better bind to human ace2 receptors was just too many coincidences. You have to admit it's believable. But then when you realize how many people in rural China have b…

The whole lab thing is people getting cause and effect mixed up, the lab is there because novel coronaviruses keep happening in that region, but because all people know is that COVID-19 is new (and none of the history) they immediately jump to that the lab specializing in this type of disease at the epicenter is too big of a coincidence to ignore (rather than it being there exactly because it is a common epicenter).…

The lab theory is better suited for a movie, as no hard evidence has been presented.

Oddly enough, it seems the virus will end up transmitting the Chinese control over its people to several western countries.

At least where I live a quite scary addendum to the current epidemic law has been presented. If passed, it will grant the possibility to test people at an event and fine those that won't comply.

Re: Israeli startup claims Covid-19 likely originated in a lab, willing to bet on it

#254

Peter Daszak, the president of the EcoHealth Alliance researching the origins of pandemics, pointed out in April that nearly 3% of the population in China's rural farming regions near wild animals already had antibodies to coronaviruses similar to SARS. "We're finding 1 to 7 million people exposed to these viruses every year in Southeast Asia; that's the pathway. It's just so obvious to all of us working in the field…

It would make a lot of sense that SARS-COV2 was spreading in Southern China for a while, but going unnoticed, due to immunity. Then, as soon as one of those rural workers visits another major city further up north, it gets a chance to spread in a more susceptible population.

Re: Israeli startup claims Covid-19 likely originated in a lab, willing to bet on it

#255
post #247

Peter Daszak, the president of the EcoHealth Alliance researching the origins of pandemics, pointed out in April that nearly 3% of the population in China's rural farming regions near wild animals already had antibodies to coronaviruses similar to SARS. "We're finding 1 to 7 million people exposed to these viruses every year in Southeast Asia; that's the pathway. It's just so obvious to all of us working in the field…

Yeah, I initially thought having a big bio lab in the city where the pandemic started, in a country with a history of managing security in their bio labs poorly, in a lab known for studying sars like coronaviruses, including gain of function research to better bind to human ace2 receptors was just too many coincidences. You have to admit it's believable. But then when you realize how many people in rural China have b…

This is addressed in the article, although I don't see sources, so who knows how accurate it is.

>The most similar coronavirus is found among bats that don’t live nearby, and scientists have not been able to pinpoint the exact point where SARS-CoV-2 transferred to humans

Re: Israeli startup claims Covid-19 likely originated in a lab, willing to bet on it

#256
post #143

Earlier quoted context omitted.

And that is very solid bayesian logic. Wuhan has the only BSL-4 lab in China, and was specifically working on gain-of-function research on coronaviruses. The initial prior of zoonotic origin simply because that was usually the case in the past is just as circumstantial, but also just as solid in bayesian terms.

> Wuhan has the only BSL-4 lab in China The Harbin Veterinary Research Institute in Heilongjiang is another BSL-4 lab

Fair enough, but it had only been operational for a year at the time of the outbreak and is focused on veterinary science.

Re: Israeli startup claims Covid-19 likely originated in a lab, willing to bet on it

#257
post #247

Earlier quoted context omitted.

Yeah, I initially thought having a big bio lab in the city where the pandemic started, in a country with a history of managing security in their bio labs poorly, in a lab known for studying sars like coronaviruses, including gain of function research to better bind to human ace2 receptors was just too many coincidences. You have to admit it's believable. But then when you realize how many people in rural China have b…

The whole lab thing is people getting cause and effect mixed up, the lab is there because novel coronaviruses keep happening in that region, but because all people know is that COVID-19 is new (and none of the history) they immediately jump to that the lab specializing in this type of disease at the epicenter is too big of a coincidence to ignore (rather than it being there exactly because it is a common epicenter).…

> The whole lab thing is people getting cause and effect mixed up, the lab is there because novel coronaviruses keep happening in that region...

That is not the case, the outbreak in Wuhan came as a surprise even to the virologists there.

The region where you would expect this to happen is Southern China, where there's bats living close to humans, not Wuhan, where there aren't any bats at all.

The virologists in Wuhan had to travel hundreds of miles to Southern China to collect samples from bats.

Re: Israeli startup claims Covid-19 likely originated in a lab, willing to bet on it

#258

Peter Daszak, the president of the EcoHealth Alliance researching the origins of pandemics, pointed out in April that nearly 3% of the population in China's rural farming regions near wild animals already had antibodies to coronaviruses similar to SARS. "We're finding 1 to 7 million people exposed to these viruses every year in Southeast Asia; that's the pathway. It's just so obvious to all of us working in the field…

It would make a lot of sense that SARS-COV2 was spreading in Southern China for a while, but going unnoticed, due to immunity. Then, as soon as one of those rural workers visits another major city further up north, it gets a chance to spread in a more susceptible population.

I dont find that very plausible. There aren't really any places on earth with that many people AND that isolated from the rest of us. For it to be common among them for a long time without escape? I'm not buying it, at least at this level of discussion.

Re: Israeli startup claims Covid-19 likely originated in a lab, willing to bet on it

#259

Peter Daszak, the president of the EcoHealth Alliance researching the origins of pandemics, pointed out in April that nearly 3% of the population in China's rural farming regions near wild animals already had antibodies to coronaviruses similar to SARS. "We're finding 1 to 7 million people exposed to these viruses every year in Southeast Asia; that's the pathway. It's just so obvious to all of us working in the field…

SARS was a thing in China, so that's not surprising. The discussion is about SARS-CoV2. Now they are a few small mutations away that would be significant.

Re: Israeli startup claims Covid-19 likely originated in a lab, willing to bet on it

#260

Earlier quoted context omitted.

The Wuhan lab being specialized in bat viruses means very little. For one thing, this is a classic example of correlation != causation. Let’s say you had a shark attack on some beach and there was a team researching shark attack located right in that area. Would you then conclude that the team engineered the shark attack? The simple reality is that the most likely reason the team studying shark attacks is located in…

Everything that I've read suggests the bats from which the virus likely originated can only be found hundreds of kilometers away, so it must have been brought into Wuhan somehow. Either for food, or for research, unless you can propose another explanation? > The bats carrying CoV ZC45 were originally found in Yunnan or Zhejiang province, both of which were more than 900 kilometers away from the seafood market. Bats w…

With asymptomatic transmission the virus likely would have spread unnoticed in the town that was encroaching on bats for a while before someone brought it to Wuhan.
Post reply on HN