361–370 of 436 posts
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You are not alone. We just have to use throwaway accounts and hide in catacombs like early Christians.
Please don't compare this nonsense to that.
It’s only in hindsight that we realize that the early christians were quite sane compared to what we have now.
Same with the Oxford / AstraZeneca vaccine "No hospitalizations or severe cases of COVID-19 were reported in those receiving the vaccine." https://apnews.com/article/astrazeneca-vaccine-third-cheaper... They all seem quite promising.
https://blogs.sciencemag.org/pipeline/archives/2020/11/23/ox...
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Yes i read some interesting article aswell regarding mRNA vaccines, but from my understanting mRNA vaccine aren't yet tested in humans right? Only animals or am i mistaken? EDIT: what my question is: is there another mRNA type vaccine out there fully developed (i'm not suggesting that they are bad!)? EDIT2: Guys, i will never ask question again in here. Begin downvoted for a genuine question.
You're probably being downvoted because this information is easily looked up. https://en.m.wikipedia.org/wiki/RNA_vaccine
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An individually tailored cancer treatment is already available in the form of the CAR-T therapies, which might give an indication of how expensive it’ll be - you were pretty much right on the dot, since each treatment in a course of treatments is estimated at $375,000.
In order to produce a personalized anti-cancer RNA vaccine, you need to a) do a biopsy of the tumor and some healthy tissue, which is fairly cheap, b) do genetic analysis of those samples to find the differences. This used to be prohibitively expensive, but now is fairly cheap too, the price went down six (!) orders of magnitude since 2000, c) ask specialized software to find the optimal protein set to express. This…
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Are the trial participants exposed to the virus purposefully or is the result that none of participants developed covid just from regular daily living?
There's a (blinded) control group so purely based on how deeply unethical it would be to purposefully expose them to the virus I'd wager they were 'natural' occurrences.
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> Antisense drugs are much simpler, with no immune response required. The mRNA (the drug) itself simply binds to the target mRNA. Does that make them a class of "cures" rather than "immunizations"? If I get infected with the same thing a year later, will I need another dose of the antisense drug?
Yes, they are "cures". Yes, you will.
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This is a bit much for me to read without the right background. I'll focus on your claim, though. "Sending mRNA to human cells to produce viral proteins" describe how all of the other vaccines work. You're saying that this one uses DNA. I don't know if that's a typo or if that's an important difference. However from what I understand, the two other vaccines people are talking about don't change any of the genetic mat…
Yes, this one uses a DNA virus as a way to deposit a piece of DNA into the nucleus of a cell, so that it makes viral proteins the way cells usually do. The virus used is incapable of replication so it only has the cell entry features, not the viral propagation features.
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In order to produce a personalized anti-cancer RNA vaccine, you need to a) do a biopsy of the tumor and some healthy tissue, which is fairly cheap, b) do genetic analysis of those samples to find the differences. This used to be prohibitively expensive, but now is fairly cheap too, the price went down six (!) orders of magnitude since 2000, c) ask specialized software to find the optimal protein set to express. This…
If a parent and child develop the same cancer, is it any more likely that the same (mRNA) drug will work for both of them? Or do cancer cells mutate so much that they're unrecognizable between patients? It would have interesting implications if in the future a family could invest in a bank of mrna molecules for their future generations. A new form of wealth.
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You can't just multiply the cost for 1 person by the number of people in the population. If it's mass produced it will be a lot cheaper. e.g. if you want to pay a chemist to synthesise Aspirin in a lab for you it will be very expensive. But it costs pennies in the store.
That's only true if you can use the same aspirin as many other people. If the specific substance needs to be adjusted to your specific tumor, it may remain extremely expensive for a long time - until it becomes a technician's job to find your specific cancer signature and synthesize the drug from it.
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Plus the fact that they want us to let them hack our DNA. It's a bit like giving them root to the OS of my being.
No, mRNA is not DNA.