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No one who got Moderna's vaccine in trial developed severe Covid-19

sciencemag.org

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Re: No one who got Moderna's vaccine in trial developed severe Covid-19

#2
RNA vaccines have a huge potential in treating cancer as well. Basically, you can whip up a personalized vaccine which wakes the immune system up to the fact that it has a growing tumor on its hands.

So far, the success rate is very far from 100 per cent, but the therapy sometimes works even in patients with severe late stage metastatized cancer and, in all likelihood, we will learn how to use it better in coming years.

This progress could save way more lives down the line than just those at risk with Covid.

https://www.nature.com/articles/d41586-019-03072-8

Re: No one who got Moderna's vaccine in trial developed severe Covid-19

#3

RNA vaccines have a huge potential in treating cancer as well. Basically, you can whip up a personalized vaccine which wakes the immune system up to the fact that it has a growing tumor on its hands. So far, the success rate is very far from 100 per cent, but the therapy sometimes works even in patients with severe late stage metastatized cancer and, in all likelihood, we will learn how to use it better in coming yea…

if mRNA works in anything close to a general case, i’m beginning to think that it might be as fundamentally transformative as the move from sulfa drugs to antibiotics was.

Re: No one who got Moderna's vaccine in trial developed severe Covid-19

#5

RNA vaccines have a huge potential in treating cancer as well. Basically, you can whip up a personalized vaccine which wakes the immune system up to the fact that it has a growing tumor on its hands. So far, the success rate is very far from 100 per cent, but the therapy sometimes works even in patients with severe late stage metastatized cancer and, in all likelihood, we will learn how to use it better in coming yea…

if mRNA works in anything close to a general case, i’m beginning to think that it might be as fundamentally transformative as the move from sulfa drugs to antibiotics was.

I do not know if you aware or not, but there is a similar to mRNA vaccines, yet different (actually, almost mirror reflection of what mRNA vaccine is) invention called antisense drugs. Those are actually already used as antivirals.

Re: No one who got Moderna's vaccine in trial developed severe Covid-19

#6

RNA vaccines have a huge potential in treating cancer as well. Basically, you can whip up a personalized vaccine which wakes the immune system up to the fact that it has a growing tumor on its hands. So far, the success rate is very far from 100 per cent, but the therapy sometimes works even in patients with severe late stage metastatized cancer and, in all likelihood, we will learn how to use it better in coming yea…

Yes i read some interesting article aswell regarding mRNA vaccines, but from my understanting mRNA vaccine aren't yet tested in humans right? Only animals or am i mistaken?

EDIT: what my question is: is there another mRNA type vaccine out there fully developed (i'm not suggesting that they are bad!)?

EDIT2: Guys, i will never ask question again in here. Begin downvoted for a genuine question.

Re: No one who got Moderna's vaccine in trial developed severe Covid-19

#7
>>> Anti-vaxxers immediately jump on any report of possible adverse events in a vaccine trial (which are thoroughly investigated, of course).

>>> Let’s spare a thought today for the person who signed up for the Moderna vaccine trial, received two placebo shots and died of covid19.

https://twitter.com/kakape/status/1333401133260419072

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edit:

Please explain the downvotes.

The vaccine volunteer would be alive if he was randomly assigned the actual vaccine, and not two doses of placebo.

The tweet is from a respected journalist at Science Magazine.

Re: No one who got Moderna's vaccine in trial developed severe Covid-19

#9

Earlier quoted context omitted.

if mRNA works in anything close to a general case, i’m beginning to think that it might be as fundamentally transformative as the move from sulfa drugs to antibiotics was.

I do not know if you aware or not, but there is a similar to mRNA vaccines, yet different (actually, almost mirror reflection of what mRNA vaccine is) invention called antisense drugs. Those are actually already used as antivirals.

Antisense drugs are the same biological material, but have a very different mechanism of effect.

Specifically, mRNA vaccines require an immune response to be effective. The mRNA (vaccine) encodes a viral protein, and the host (human) immune system still has to learn to respond to that protein.

Antisense drugs are much simpler, with no immune response required. The mRNA (the drug) itself simply binds to the target mRNA.

Re: No one who got Moderna's vaccine in trial developed severe Covid-19

#10

RNA vaccines have a huge potential in treating cancer as well. Basically, you can whip up a personalized vaccine which wakes the immune system up to the fact that it has a growing tumor on its hands. So far, the success rate is very far from 100 per cent, but the therapy sometimes works even in patients with severe late stage metastatized cancer and, in all likelihood, we will learn how to use it better in coming yea…

Yes i read some interesting article aswell regarding mRNA vaccines, but from my understanting mRNA vaccine aren't yet tested in humans right? Only animals or am i mistaken? EDIT: what my question is: is there another mRNA type vaccine out there fully developed (i'm not suggesting that they are bad!)? EDIT2: Guys, i will never ask question again in here. Begin downvoted for a genuine question.

They have already been tested on cancer patients, with some very promising results.

https://acir.org/weekly-digests/2020/august/rna-vaccine-for-...

https://www.sciencedaily.com/releases/2020/11/201110102550.h...

Some of the patients would probably already be dead if it wasn't for RNA vaccines.

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