Stonehenge is approx 250 metres from the A303, which is one of the main routes into the South West UK. The A303 at the closest point is a single lane in each direction, and frequently very slow at that point, so isn't massively obtrusive in the sense that a 6-lane motorway would be. That said, there is a plan to dig a tunnel nearby to get rid of the road completely.
Stonehenge is debatable as a visitor attraction, especially if you are in the UK only for a few days. By coach from London it is pretty much a full day, when there is a lot more history in London itself. In my opinion. Stonehenge itself (as opposed to the larger archaeological landscape) is small compared with Roman or Greek remains, so if you don't have an appreciation of the history of the place, may be underwhelming. It also gets crowded very quickly, although the fact that a close approach to the stones isn't usually possible means that everyone gets a view. Last time I went I arrived early, and got some great HDR images of the stones under an impressive moody sky.
[Edit - I also agree about Avebury being worth a visit. You can walk amongst the stones themselves, which are almost part of a historically pretty village. The really impressive structures in the nearby vicinity in my opinion are the hill forts such as Old Sarum [0] near Salisbury and Maiden Castle [1] near Dorchester. These are truly massive Iron Age earthworks.
[0] https://en.wikipedia.org/wiki/Old_Sarum#Prehistory
[1] https://en.wikipedia.org/wiki/Maiden_Castle,_Dorset