Bad handwriting. At age 40 I started taking a masters in stats and had situations where I had exponents on exponents. This lead me to buy a higher resolution tablet for reading pdf's with tiny math. I also bought a finer point pen and this helped me improve my handwriting a lot . Closing loops on "o's" or backtracing the upward line of a cursive "t" to not make a loop. With the finer point, I was able to see my impre…
Personally, the +/t handwriting issue has never been an issue for me: make sure you get a good tail on the t, and it's pretty easy to distinguish from a +. It's the x/× distinction that was always the most painful to distinguish for me.