The recent Amazon outage, in which actual data was lost, would seem to make a case for NOT using this.
This has nothing to do with "the cloud", hosted content or anything - Chromless is an application launcher allowing applications to launch utilizing the Firefox engine - think of it as an Adobe AIR type product.
OK, fair enough. And where are those applications hosted? If it's local to the machine, then great. If it's it's out in "the cloud", then the reliability for applications, which may have been purchased, is iffy at best.