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Vitamin D Supplementation Improves Cognitive Function: 12-month RCT

pubmed.ncbi.nlm.nih.gov

161–170 of 198 posts

Re: Vitamin D Supplementation Improves Cognitive Function: 12-month RCT

#161
post #50

My sister got leukemia while part way through her doctorate. After it went into remission, she was unable to recall new information long enough to read papers and had to put her studies on hold. Eventually a doctor did a blood test that included vitamin d levels, and she was in the single digits (don't remember units but it was supposed to be at least 20). She started supplementing and graduated this spring. Just one…

Similar story. My mind was in fragments from diseases. Vit D in low teens. Started high level vit D at start of Covid Brain function is approaching my old levels. Now I take a lot of supplements, so it’s always tricky to pin it down. But so far so goods.

Re: Vitamin D Supplementation Improves Cognitive Function: 12-month RCT

#162
post #7

Funny -- I was just digesting a competing study released recently[0] which showed little-to-no benefit from vitamin D, Omega 3 fatty acids, and exercise (either alone or in combinations). That study used 5X the daily vitamin D as this one. So I guess the jury's still out and I may choose to continue to err on the side of supplementing vitamin D. [0] https://www.upi.com/Health_News/2020/11/10/Study-Little-bene...

Or just get some sunshine! It's likely there are other benefits, besides just the vitamin D.

I’m allergic to the sun. Autoimmune. A day in full sun will mean months of agony.

Re: Vitamin D Supplementation Improves Cognitive Function: 12-month RCT

#163
post #155

Earlier quoted context omitted.

> Or just get some sunshine! Where I live I haven't been able to get sun actually on my skin for the last three weeks. I saw sunshine through the window one day last week while in a meeting, but it was gone an hour later. According to my weather app the next break in cloud is more than a week from now. Even when there is sunshine in the winter, it's often too cold to expose more than a tiny amount of skin anyway. Ple…

>Please don't assume we all live in California. Same here, although at least there's sun on weekends for me (if it isn't cloudy). Looking out the window, and being outside on the weekend with a winter hat and long sleeves is probably not allowing a lot of vitamin D. I'm wondering if there's something like a good lamp that gives UV light without being too strong.

UV bath in Russia.

https://www.nationalgeographic.com/photography/photo-of-the-...

Re: Vitamin D Supplementation Improves Cognitive Function: 12-month RCT

#164

Earlier quoted context omitted.

Pressurized airliners have about 15 air changes per hour or 3-4x what’s typical in an office building. This is air exchanges with the outside, not filtration cycles which are in addition. Even if the filters were entirely INOP, I suspect you’re no worse off than sitting in an office building. Now, I’m not doing that right now, but there’s little reason to think major US carriers aren’t doing what they say they’re doi…

Sitting in an office building is one of the worst places you can be for avoiding getting sick.

Kids kind of makes it all pointless. They catch everything and bring it home.

It was nice not being sick for so many months.

2 weeks after they went back. Bam, everyone sick.

And that’s with intense mask rules and distancing

Re: Vitamin D Supplementation Improves Cognitive Function: 12-month RCT

#165
post #40
post #34

Earlier quoted context omitted.

For reference: The level of toxicity listed in your link is 60,000IU per day. Fauci said he takes 10,000IU per day. The bottle I purchased recommends 2,000IU per day. Get your blood work done people.

There's an expert that specializes in vitamin D toxicity cases and regularly posts here. She sees cases at less than the 10000IU daily dose Fauci takes. I would be hesitant to go above 4000IU daily without monitoring blood levels every six months or so. Its winter here in Canada, I'm taking 3000IU per day. I drop that to 1000IU in the summer. I'm not a doctor, not recommending you do the same. Just sharing.

The problem is TIME. Taking 10,000 IU for a medium amount of time will very very likely be fine.

But due to fat solubility and therefore slow build up in the body, you are increasingly growing towards toxic levels over a long time.

The body can only regulate vitamin D before synthesis, after sunlight exposure. But if you take already-synthesized vitamin D, that regulation won't kick in and you're free to get hypervitaminosis.

Time in combination with individual biology are what brings issues here. Get blood work done (it cost me 30€ in Germany but was combined with 2 other tests).

Re: Vitamin D Supplementation Improves Cognitive Function: 12-month RCT

#166

Funny -- I was just digesting a competing study released recently[0] which showed little-to-no benefit from vitamin D, Omega 3 fatty acids, and exercise (either alone or in combinations). That study used 5X the daily vitamin D as this one. So I guess the jury's still out and I may choose to continue to err on the side of supplementing vitamin D. [0] https://www.upi.com/Health_News/2020/11/10/Study-Little-bene...

> 40.7% of participants had 25(OH)D levels of less than 20 ng/mL at baseline, and according to current guidelines, all were allowed to take 800 IU/d of supplemental vitamin D outside the study medication. So, even the controls were given D3 supplements if they were deficient. That kind of throws the whole study into question.

It might also be worth mentioning that measuring 25-hydroxy is also an approximation at best. That still has to be converted to 1,25-dihydroxyvitamin by the kidneys. People with high insulin resistance (diabetics, pre-diabetics) or kidney damage tend to have problems converting 25-hydroxy. Measuring 25-hydroxy is primarily used for toxicity and even that has variables that are difficult to measure, so a statistical baseline is applied.

Re: Vitamin D Supplementation Improves Cognitive Function: 12-month RCT

#167

Earlier quoted context omitted.

Sitting in an office building is one of the worst places you can be for avoiding getting sick.

Kids kind of makes it all pointless. They catch everything and bring it home. It was nice not being sick for so many months. 2 weeks after they went back. Bam, everyone sick. And that’s with intense mask rules and distancing

You're not wrong, but that doesn't mean that we can't take other measures to get back below R=1. The primary one I can think of is for governments of the world to give long term contracts to N95 mask makers so they can fully spin up their factories. It's been 9 months for $diety's sake.

Non-fit homemade and non-rated masks help prevent others from getting sick. But if everyone had access to cheap N95 that actually prevented them from getting sick we'd be a lot better off. The kids would still be getting it and getting everyone sick at home/school because they wouldn't wear them consistently right, but people without kids at home wouldn't be getting sick at nearly the rate. Every bit counts.

Re: Vitamin D Supplementation Improves Cognitive Function: 12-month RCT

#168
post #34

Earlier quoted context omitted.

For reference: The level of toxicity listed in your link is 60,000IU per day. Fauci said he takes 10,000IU per day. The bottle I purchased recommends 2,000IU per day. Get your blood work done people.

Source for the Fauci claim? I've seen a claim of 6000 (not sourced properly), the RDA is 600, I couldn't find even a dubious source for 10000 and all decent sources didn't give a dose at all. Given that 10000 is considered more than the maximum safe amount by many health authorities, I doubt Fauci would say he's taking that much even if he did.

The Big Vitamin D Mistake: https://pubmed.ncbi.nlm.nih.gov/28768407/

> A statistical error in the estimation of the recommended dietary allowance (RDA) for vitamin D was recently discovered; in a correct analysis of the data used by the Institute of Medicine, it was found that 8895 IU/d was needed for 97.5% of individuals to achieve values ≥50 nmol/L.

> This could lead to a recommendation of 1000 IU for children 1 year of age, and around 8000 IU for young adults and thereafter.

Re: Vitamin D Supplementation Improves Cognitive Function: 12-month RCT

#170

You know I use a vitamin d supplement because I'm not a big outdoors guy and I livein the northern USA and I was deficient at my last annual inspection. That said why does HN seem to have a vitamin D story everyday? It's not a magic pill. If you have deficient levels you should do something about it, but it's not a cure all.

HN seem to love three health subjects:

1 - Vitamin D

2 - Fasting

3 - Did I mention fasting?

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