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Covid vaccine: First ‘milestone’ vaccine offers 90% protection

bbc.co.uk

451–460 of 1001 posts

Re: Covid vaccine: First ‘milestone’ vaccine offers 90% protection

#451
post #17

Seems like a good time to buy shares in whoever manufactures industrial sized extra cold freezers.

Seems like a good time to own shares in literally anything. The DJI is going to open up 1,500 points at least.

I initially thought so too, but there are some big losers in the market today - think home delivery (Ocado) , entertainment (Netflix), and more interestingly specialist Covid test suppliers.

Re: Covid vaccine: First ‘milestone’ vaccine offers 90% protection

#452
post #409

Earlier quoted context omitted.

This may be true for urban/suburban US/Europe/China/India, but this is not true for large parts of the world. There are parts of rural US/Australia for example where despite people having cars, they may need to take a plane to get to a vaccine treatment centre with enough density to get stock. They may not be able to afford that travel even if the vaccine is free. Much of the African population is spread over small c…

There are still other vaccines in testing that will be more suitable for those parts of the world.

Yes and that's a good thing. I think it's still important to recognise that not everyone is as privileged as many of us here, and that an inclusive approach to distribution will be important for this vaccine.

Re: Covid vaccine: First ‘milestone’ vaccine offers 90% protection

#453

Earlier quoted context omitted.

+ ~90% of individuals achieve immunity It could also refer to 90% reduced severity. A 60% vaccine can reduce the severity of the illness by 40% so only 40% of the expected number end up in hospital.

I thought it was that 90% show production of antibodies.

No, they showed an antibody response in the spring. That's the easy part. This is the real-deal clinical trial: they gave tens of thousands of people the vaccine candidate, tens of thousands a placebo, and then counted the resulting cases for months, as well as watching for side effects. The 90% reduction is in actual cases.

Re: Covid vaccine: First ‘milestone’ vaccine offers 90% protection

#454
post #17

Seems like a good time to buy shares in whoever manufactures industrial sized extra cold freezers.

Seems like a good time to own shares in literally anything. The DJI is going to open up 1,500 points at least.

Except ZM

Re: Covid vaccine: First ‘milestone’ vaccine offers 90% protection

#455

Earlier quoted context omitted.

I think we can eradicate it by contact tracing. With 90% efficiency it will be extremely tough for the virus to spread. For any new cases you simply test everyone in the vicinity of the infected person. But I don't think even that will be necessary. 90% efficiency reduces R so much, it will probably die out on its own. The real problem is mutations that are not covered by the vaccine. If it mutates as efficiently as…

This is 90% protection against disease, not necessarily 90% protection against infection. There's an important distinction: * Protection against disease means that you don't get sick. You may still contract the virus and spread it to others (the Salk vaccine against Polio works this way). * Sterilizing immunity means that you can't even get infected, so that you can't pass the virus on to other people. It does not lo…

Without sterilizing immunity, will the amount of virus a vaccinated individual carries match that of a non vaccinated individual, though? I guess what I (a layman) is asking is, even if the vaccinated individual contracts the virus, won't they spread less of it than someone truly sick?

Re: Covid vaccine: First ‘milestone’ vaccine offers 90% protection

#456

Earlier quoted context omitted.

This is great and all, and I'm not against vaccinations, but is this safe long term? Am I the only one here who doesn't want to get inoculated in basically the first batch?

Risk of COVID19 long term effects is far worse than mRNA side effects IMO.

We do not know yet.

Re: Covid vaccine: First ‘milestone’ vaccine offers 90% protection

#457
post #439

Earlier quoted context omitted.

> but is this safe long term Is getting COVID safe long term? There are plenty of viruses that cause issues in the long term. HIV causes AIDS, HPV and Hepatitis cause cancers years later. We have no clue on the long term effects of SARS-Cov-2, other than that it causes COVID-19 in the short term. It's a choice between the pest and the cholera at this point.

> Is getting COVID safe long term? For most people yes edit: so the whole world is studying this virus 24/7 for almost a year and nobody detected anything, yet you think it might give us aids v2 ? Feel free to link any study that hints to anything remotely going in that direction because I couldn't find anything at all.

We cannot be sure. Like, we have no idea.

Re: Covid vaccine: First ‘milestone’ vaccine offers 90% protection

#458

Earlier quoted context omitted.

My understanding is that -80c cold storage isn't widely available. The Ebola outbreak might have shown how to get small numbers of doses into a warzone, but scaling this up might prove to be a logistical difficulty. "Once a provider receives that vaccine, it really starts the clock that the vaccine needs to be administered within five days of when it's put in the refrigerator" Source: https://www.cbsnews.com/news/cor…

Sure it is. Any small city (> 50,000 people) has someone who can get you liquid nitrogen in far larger quantities than will ever be needed (thus stuff is used for a lot of industrial processes). Put it in a cooler from wal-mart and you have a week. Any you get a week after thawing it to use is anyway, so you don't need the cold storage where the end user is. I don't know what the thawing protocols are of course.

i'm involved in some state government COVID vaccine projects. The issue is you can't just knock together cold storage like this, there's (naturally) a long process to get "approved" and "certified" for vaccine administration. Storage is one of these criteria, they're not going to hand over a batch of vaccine to some doc with a cooler of dry ice.

Re: Covid vaccine: First ‘milestone’ vaccine offers 90% protection

#459

Earlier quoted context omitted.

Depends on the scale - we are talking mass vaccination of the whole planet here.

Not really, if every airport runs a vaccination program that takes 2 months before someone can fly there's very little need for more global infrastructure. The problem with lockdowns, etc is reinfection mostly by air travellers.

How could that possibly be the problem?

This maybe _was_ the problem in the beginning of the pandemic. Now, it's in the general population and will spread even if you ban all airplanes and repurpose airports into petting zoos.

Re: Covid vaccine: First ‘milestone’ vaccine offers 90% protection

#460
post #335

Earlier quoted context omitted.

Look, I get that you find lockdowns an inconvenience but the real world isn’t a TV show where a cheap and easily distributed cure will be invented 10 minutes before the end of the episode. People will reliably die until a vaccine or highly effective treatment is widely available, and the only way to slow that is to rely on proven public health techniques. While you’re being inconvenienced remember that you’re better…

You criticized the commenter for objecting to lockdown. Why are the people you refer to dying? Is it possible it is because they aren't quarantining and staying at home?

Nobody can 100% stay home. The more every does though the better the less than 100% works. When someone getting their prescriptions refills gets it they are just as sick as someone who goes to a bar and gets it. The only difference is someone who goes to a bar is out a lot more and so has a higher chance of getting it.
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