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Covid vaccine: First ‘milestone’ vaccine offers 90% protection

bbc.co.uk

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Re: Covid vaccine: First ‘milestone’ vaccine offers 90% protection

#161

Post by bipson »

jefftk wrote: post #67
bjarneh wrote: post #27

Earlier quoted context omitted.

> what would it even mean for somebody to be "90% immune" to a disease? Hasn't this virus already mutated to a bunch of different strands? Could it mean you're immune to 90% of the known variations of the virus?

The variations are enough to have differences in infectiousness and to allow us to trace the spread a bit, but as far as we know immunity to any of them is immunity to all of them.

I think someone should clarify the strands vs. genetic variations here.

Because the reports from Denmarks Mink fiasco indicated that antibodies were not as effective on the mutation that appeared there short time ago. This would contradict the one-fits-all immunity argument.

Re: Covid vaccine: First ‘milestone’ vaccine offers 90% protection

#162

Post by andrepd »

mettamage wrote: post #117
strombofulous wrote: post #82

Earlier quoted context omitted.

I don't understand, aren't future events supposed to be already considered in the stock price? It's not like a vaccine was unpredictable

+1 Thanks for putting it so succinctly. I really hope someone who knows a thing or two about the efficient market hypothesis can elighten us a bit.

Well, it's bullshit x)

Re: Covid vaccine: First ‘milestone’ vaccine offers 90% protection

#163

Post by Eric_WVGG »

andy_ppp wrote: post #133
empthought wrote: post #45

Earlier quoted context omitted.

The RNA is read by human cells and the spike protein antigen is created by human cells; it’s not particularly viral RNA.

Okay pretty terrifying! How long does this random RNA stay in your cells?

There’s nothing random about it.

Here’s a good layperson rundown: https://www.phgfoundation.org/briefing/rna-vaccines

Re: Covid vaccine: First ‘milestone’ vaccine offers 90% protection

#164

Post by romanovcode »

tuna-piano wrote: post #153

For those wondering how their vaccines will be distributed among countries during the next year when supply is constrained... it seems complicated. Pfizer is a US company, but has at least one key ingredient from Austria, is made with technology from Germany, has manufacturing in US+Europe, etc. Pfizer's CEO answered this question this morning on CNBC. Pfizer has two separate manufacturing divisions- one in the US (M…

Why not share the knowledge make the vaccine in all three countries? AFAIK for the last 2-3 days EU and US are partners again, not enemies.

Re: Covid vaccine: First ‘milestone’ vaccine offers 90% protection

#165

Post by woofie11 »

howlgarnish wrote: post #130
rq1 wrote: post #87

The virus is (heavily) mutating folks. Heavy mutations likely related to recombination with rhino-viruses. This vaccine will likely be outdated when generally available.

The mutations seen so far are minor and don't appear to impact our ability to vaccinate against them.

Rate of mutations is directly proportional to number of viruses out there. We're having exponential growth in the amount of COVID19 (with a slow exponent, with social distancing, but exponential none-the-less). That we've seen mutations back when there was a tiny fraction of the cases we have today is a very bad sign.

If it jumps species, as we saw with mink, we may have a reservoir in nature with no control. It will mutate and periodically jump back to humans.

Re: Covid vaccine: First ‘milestone’ vaccine offers 90% protection

#166

Post by fuoqi »

nsoonhui wrote: post #38

Just curious, why the reaction towards this and the ones from Russia/China are different ?

Obviously because of the geopolitical concerns and pride. Truth is the first victim as usual. The Russian vaccine was indeed registered just after the 2nd phase trials, but according to its website the 3rd phase trial has started on August 25 (one month later than for BNT162b2) and involved more than 40k people (effectively the same number).

So those who claim that Russian vaccine is only on the 1/2 phase spread an outright lie. Both vaccine have approximately the same speed of development with minor differences between regulation and testing procedures.

Re: Covid vaccine: First ‘milestone’ vaccine offers 90% protection

#167

Post by andrepd »

nsoonhui wrote: post #38

Just curious, why the reaction towards this and the ones from Russia/China are different ?

Trust. Russia and China lie through their teeth on everything and anything. It's irrelevant whether or not they are lying in this particular instance: they cannot be trusted.

Re: Covid vaccine: First ‘milestone’ vaccine offers 90% protection

#168

Post by sojuz151 »

drchiu wrote: post #105

I read this with a lot of hope. The -80 degree cold storage part won’t be easy. Most vaccines stored at medical offices are nowhere near that and are only around ~0 degrees C. Freezer temps are only ~18 deg C. Possibly will only be able to be administered at special sites or if they find a way to stabilize it at warmer temp.

Or just keep it in liquid nitrogen. Its is cheap and cold enough.

Re: Covid vaccine: First ‘milestone’ vaccine offers 90% protection

#169

Post by carlmr »

usrusr wrote: post #160
carlmr wrote: post #20

Earlier quoted context omitted.

I would assume something like with the influenza vaccine, where you have immunity to i think around 70% of currently available virus mutations, if the vaccine works.

That's a percentage on a different axis. Influenza is a diverse family of related viruses and strains vary much more than those of SARS-COV-2. No surprise given the very different time since taking foot in humans, and in addition to that (I think, working on weak knowledge here) that influenza is even part of a group of viruses that is prone to create mashup versions of itself when two strains meet in the same host.…

I'm explaining a concept, nothing specific to the flu or covid.

I'm just saying how you can have a single person that's 90% immune to something vs. Having 90% of people immune against one strain of a virus.

Re: Covid vaccine: First ‘milestone’ vaccine offers 90% protection

#170

Post by tomrod »

krzyk wrote: post #11
WhoIsSatoshi wrote: post #7

UK already ordered 30M out of the 50M avail for this year. So no going on winter break to Thailand just yet! Wondering who will grab the next 20M, and how much this vaccine is being sold per dose. (edit: PFE is currently trading +13% pre-market on the NYSE)

And what are the side effects.

My thought exactly.
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