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Covid vaccine: First ‘milestone’ vaccine offers 90% protection

bbc.co.uk

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Re: Covid vaccine: First ‘milestone’ vaccine offers 90% protection

#44
Hopefully there is more better scientific data on this vaccine before rushing it to top of HN and judgement. I am not sure how to explain 90% immunity from a disease in scientific language, because there are only two states a person get infected with COVID-19 or does not get infected with COVID-19. Not sure how this vaccine will make a person 10% infected and 90% not infected with COVID-19.

This is one of the vaccine Trump referred to in his debate, not sure how much it’s really useful or its another one like Sputnik and Coronavac.

I think the best details for Corona related vaccine efforts are from WHO. [1]

[1] https://www.who.int/publications/m/item/draft-landscape-of-c...

Re: Covid vaccine: First ‘milestone’ vaccine offers 90% protection

#45
post #23

Also interesting to note that this is a mRNA vaccine, where the production of antigen within the cell is induced by injecting a RNA sequence instead of a disabled virus.

What extra does a virus have over and above some RNA? Is it just a spike protein for injection into a cell or does it depend?

The RNA is read by human cells and the spike protein antigen is created by human cells; it’s not particularly viral RNA.

Re: Covid vaccine: First ‘milestone’ vaccine offers 90% protection

#46
Fascinating logistics problem here - distributing a vaccine that needs to be stored at -80C.

This is significantly colder than the standard cold logistics chain. I believe Pfizer are working on a special transport box that can, unpowered, stay at the right temperature for a week as long as the box is only opened for something like 1 minute a day.

That's a good thing, but with a capacity of I believe 10k vaccine doses, anywhere with fewer than 10k people to vaccinate, or anywhere that can't keep the demand level for the vaccine at the right level each hour/day as they progress through their vaccine stock, will have a hard time. This is going to disproportionately affect small communities and developing countries.

We've got hard logistical challenges ahead regardless of these details, but they make this even harder. Given this it's probably important that we continue to develop more vaccines and diversify our strategy for immunity.

Re: Covid vaccine: First ‘milestone’ vaccine offers 90% protection

#47
Also if anyone gets the China Convid

This is the actual Cure without a magic needle:

* Hrdroxy chloroquine (HCQ) and Azithromycin for 6 days cures a person

Take 2 200mg HCQ chloroquine pills per day, along with Azithromycin 500g once a day, + Zinc Supplments 200mg once a day

Also supplment that with Vit C+D

Above is 100% cure rate no magic needle

Re: Covid vaccine: First ‘milestone’ vaccine offers 90% protection

#49
post #13

UK already ordered 30M out of the 50M avail for this year. So no going on winter break to Thailand just yet! Wondering who will grab the next 20M, and how much this vaccine is being sold per dose. (edit: PFE is currently trading +13% pre-market on the NYSE)

At least in the US "Pfizer and BioNTech will sell their mRNA-based COVID-19 vaccine to the U.S. government at an estimated cost of $19.50 per shot..." https://www.fiercepharma.com/pharma/pfizer-biontech-s-u-s-su...

=> projected cost to the customer seem to be ~ 80/100 per shot with 2 shots needed (if we go with a $20 base + $80 premium)
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