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Covid vaccine: First ‘milestone’ vaccine offers 90% protection

bbc.co.uk

11–20 of 1001 posts

Re: Covid vaccine: First ‘milestone’ vaccine offers 90% protection

#11

UK already ordered 30M out of the 50M avail for this year. So no going on winter break to Thailand just yet! Wondering who will grab the next 20M, and how much this vaccine is being sold per dose. (edit: PFE is currently trading +13% pre-market on the NYSE)

And what are the side effects.

Re: Covid vaccine: First ‘milestone’ vaccine offers 90% protection

#13

UK already ordered 30M out of the 50M avail for this year. So no going on winter break to Thailand just yet! Wondering who will grab the next 20M, and how much this vaccine is being sold per dose. (edit: PFE is currently trading +13% pre-market on the NYSE)

At least in the US "Pfizer and BioNTech will sell their mRNA-based COVID-19 vaccine to the U.S. government at an estimated cost of $19.50 per shot..."

https://www.fiercepharma.com/pharma/pfizer-biontech-s-u-s-su...

Re: Covid vaccine: First ‘milestone’ vaccine offers 90% protection

#14
post #10
post #5

At the time of writing (2020-11-09 12:04 UTC) the article uses "90% of people" and "90% protection" interchangeably. I assume it means "90% of individuals achieve immunity", rather than "individuals achieve 90% immunity". EDIT: See child comment re: Pfizer press release. EDIT 2: See [1] for said press release, which has more detailed information than the BBC article. [1] https://investors.pfizer.com/investor-news/pre…

From Pfizer's press release, they use "vaccine efficacy" which has a very specific definition. "Vaccine efficacy is the percentage reduction of disease in a vaccinated group of people compared to an unvaccinated group" So basically a 90% reduction in Covid infection.

Thank you, do you happen to have a link?

Re: Covid vaccine: First ‘milestone’ vaccine offers 90% protection

#15
post #5

At the time of writing (2020-11-09 12:04 UTC) the article uses "90% of people" and "90% protection" interchangeably. I assume it means "90% of individuals achieve immunity", rather than "individuals achieve 90% immunity". EDIT: See child comment re: Pfizer press release. EDIT 2: See [1] for said press release, which has more detailed information than the BBC article. [1] https://investors.pfizer.com/investor-news/pre…

First phrasing makes more sense than the second one to me -- what would it even mean for somebody to be "90% immune" to a disease?

Re: Covid vaccine: First ‘milestone’ vaccine offers 90% protection

#16
Pfizer's press release with more information: https://www.businesswire.com/news/home/20201109005539/en/

- Vaccine candidate was found to be more than 90% effective in preventing COVID-19 in participants without evidence of prior SARS-CoV-2 infection in the first interim efficacy analysis

- Analysis evaluated 94 confirmed cases of COVID-19 in trial participants

- Study enrolled 43,538 participants, with 42% having diverse backgrounds, and no serious safety concerns have been observed; Safety and additional efficacy data continue to be collected

- Submission for Emergency Use Authorization (EUA) to the U.S. Food and Drug Administration (FDA) planned for soon after the required safety milestone is achieved, which is currently expected to occur in the third week of November

- Clinical trial to continue through to final analysis at 164 confirmed cases in order to collect further data and characterize the vaccine candidate’s performance against other study endpoints

Re: Covid vaccine: First ‘milestone’ vaccine offers 90% protection

#18

Great news and the markets are reacting very positively to the news as well which indicates to me this could be the beginning of the end!

I remember that in March somebody posted here an entry saying that mutation of the virus will make vaccinations only useful in the short term. Were these concerns already addressed at this stage?

We have seen mutations due to minks recently which could make the vaccinations ineffective. These mutations might have been controlled but similar situations may arise in the next years.

For these reasons I am not entirely sure this is the beginning of the end.

Re: Covid vaccine: First ‘milestone’ vaccine offers 90% protection

#19
post #5

At the time of writing (2020-11-09 12:04 UTC) the article uses "90% of people" and "90% protection" interchangeably. I assume it means "90% of individuals achieve immunity", rather than "individuals achieve 90% immunity". EDIT: See child comment re: Pfizer press release. EDIT 2: See [1] for said press release, which has more detailed information than the BBC article. [1] https://investors.pfizer.com/investor-news/pre…

First phrasing makes more sense than the second one to me -- what would it even mean for somebody to be "90% immune" to a disease?

only your feet get ill

Re: Covid vaccine: First ‘milestone’ vaccine offers 90% protection

#20
post #5

At the time of writing (2020-11-09 12:04 UTC) the article uses "90% of people" and "90% protection" interchangeably. I assume it means "90% of individuals achieve immunity", rather than "individuals achieve 90% immunity". EDIT: See child comment re: Pfizer press release. EDIT 2: See [1] for said press release, which has more detailed information than the BBC article. [1] https://investors.pfizer.com/investor-news/pre…

First phrasing makes more sense than the second one to me -- what would it even mean for somebody to be "90% immune" to a disease?

I would assume something like with the influenza vaccine, where you have immunity to i think around 70% of currently available virus mutations, if the vaccine works.
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