Effects of Psilocybin-Assisted Therapy on Major Depressive Disorder
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Re: Effects of Psilocybin-Assisted Therapy on Major Depressive Disorder
#2the most important sentence from this paper for a TL;DR:
"This randomized clinical trial found that psilocybin-assisted therapy was efficacious in producing large, rapid, and sustained antidepressant effects in patients with major depressive disorder."
Re: Effects of Psilocybin-Assisted Therapy on Major Depressive Disorder
#3I'm glad that there is clinical trials for this, but here I am silently waiting for Psilocybin to be legally available.
Re: Effects of Psilocybin-Assisted Therapy on Major Depressive Disorder
#4I'm glad that there is clinical trials for this, but here I am silently waiting for Psilocybin to be legally available.
Not sure where you live, but Oregon just legalized psilocybin. Given the path blazed (ahem) by marijuana, there's cause for optimism other states will follow.
Re: Effects of Psilocybin-Assisted Therapy on Major Depressive Disorder
#5Previously: https://news.ycombinator.com/item?id=24993519
Note that Ketamine already has quite a lot of evidence for effectiveness.
Re: Effects of Psilocybin-Assisted Therapy on Major Depressive Disorder
#6I don't get how the article can claim "large, rapid, and sustained antidepressant effects" when their data is from a self-reported 1-month follow-up.
Re: Effects of Psilocybin-Assisted Therapy on Major Depressive Disorder
#7What's the current thinking about these 'compared with delayed treatment' trials?
Re: Effects of Psilocybin-Assisted Therapy on Major Depressive Disorder
#8One day I took some it was a philosopher stone...
I almost jumped the balcony to kill myself intentionally!
Think twice before to assume it's a medicine... :D
Effects are the result of poisoning your liver...
Be careful with that :Ð
Re: Effects of Psilocybin-Assisted Therapy on Major Depressive Disorder
#9I personally do not believe that depression/anxiety can be changed purely through narcotics (natural and pharma).
From my experience, building a systematic understanding of my unconscious anxieties and consciously working to overcome them is what caused my mental health to improve.
I found the hardest part was the diagnosis of the anxieties, and that my dreams gave me the best clues (not used in the Fraudian/Jungian way).
I got a bit obsessed by it, and wrote a paper as I couldn't find anyone suggesting the same theory as me: https://psyarxiv.com/k6trz. It was discussed on HN here: https://news.ycombinator.com/item?id=19143590
Re: Effects of Psilocybin-Assisted Therapy on Major Depressive Disorder
#10I don't get how the article can claim "large, rapid, and sustained antidepressant effects" when their data is from a self-reported 1-month follow-up.
I think they mean sustained consistently over that month.