Earlier quoted context omitted.
I believe many who have taken psilocybin for medical reasons would agree: they would never take it again. I did not find it not habit forming. (edited to make clear my opinion and not facts)
What do you mean? Can you elaborate?
New study finds psilocybin greatly and quickly relieves depression
141–150 of 201 posts
Re: New study finds psilocybin greatly and quickly relieves depression
#142As hopeful as I am for unconventional drugs to have more medicinal uses, is it unreasonable for me to think there's no good medicinal depression cure? Is it unfounded to think depression generally has its roots in being disconnected from other people/society? I've felt depressed before, but I've probably never had it as bad as many people. But generally I've felt depressed when my life felt too narrow. When I've felt…
I have had treatment-resistant major depression for eight years. During that time I have had long periods with extensive, frequent social interaction and bonding. My depression encompasses most of the time I've known my now-wife, repairing a broken relationship with my father, the acquisition of one new close friend, and the coming and going of many transient relationships. I don't know what the cure for my own case…
>but it works for an awful lot of people
I know CBT is awfully popular on HN. But it is worth reading into the stats on CBT. Even if you take them at face value, it certainly does not work for everyone. It is of course, most effective when there is a clear cause and effect, very effective with anxiety, and also generally with children in particular. But has been shown to be ineffective or even dangerous when used with certain cohorts, ie. significant trauma background, clinical mental illness including depression, psychosis etc.
There have been more studies on CBT than any other form of therapy, and those studies suffer from the same replication crisis that the rest of social science research does.
So if it is your first exposure to getting help (and don't get me wrong, it is good to try as a first response) and it doesn't work for you, it is not your fault. You are not 'treatment resistant', more just at a 'treatment deficit'. Generally speaking, if your counsellor says you are treatment resistant, it is time to get a new counsellor and maybe if it is warranted a referral in combination with other medical expert like a psychiatrist. Each case is different though, and you are always your own best expert in yourself.
*like pop psychology, but it burns your mouth.
Re: New study finds psilocybin greatly and quickly relieves depression
#143I mean alcohol will greatly and quickly relieve depression while you are drunk too. That is not solving anything though.
The obvious problem with this kind of study is it is hard to see this being done by objective researchers who are not quite biased towards finding benefits of psychedelic use.
Re: New study finds psilocybin greatly and quickly relieves depression
#144Earlier quoted context omitted.
The reason you cannot have a double blind study is that you can tell you've been given mushrooms. So, I expect, can the therapist and the researcher etc. The moment anyone knows it's no longer double blind. I'm happy to be corrected if there is some clever way around this. I have heard people suggest you give "control" group members so other psychoactive substance (MDMA was suggested). But that doesn't have the same…
Perhaps at low doses in total darkness?
Re: New study finds psilocybin greatly and quickly relieves depression
#145Earlier quoted context omitted.
Psychedelics have been researched since the 1960s, despite formidable legal obstacles. I'm not sure how much more "careful" you want them to be.
Cannabis is pretty heavily lobbied. I've never seen any labels indicating it can cause manic episodes on any packages. I just don't want to see that happen with anything else. We should inform people of potential side effects.
Re: New study finds psilocybin greatly and quickly relieves depression
#146As hopeful as I am for unconventional drugs to have more medicinal uses, is it unreasonable for me to think there's no good medicinal depression cure? Is it unfounded to think depression generally has its roots in being disconnected from other people/society? I've felt depressed before, but I've probably never had it as bad as many people. But generally I've felt depressed when my life felt too narrow. When I've felt…
However, medication is very effective especially as short term treatment or for major depression.
In terms of non-pharmaceutical medication, there is evidence supporting the use of St John's Wort:
A 2008 review of 29 international studies suggested that St. John’s wort may be better than a placebo and as effective as different standard prescription antidepressants for major depression of mild to moderate severity.
However:
St. John’s wort was no more effective than placebo in treating major depression of moderate severity, an NCCIH- and NIMH-funded study of 340 participants reported in 2002.
https://www.nccih.nih.gov/health/st-johns-wort-and-depressio...
Re: New study finds psilocybin greatly and quickly relieves depression
#147Earlier quoted context omitted.
The problem with that theory comes when people who have all of that and more get depressed. I do think you have a point in that the cause can be external but I think to see it as social is far too limited. Then there are cases where it's entirely internal as well, depression being a symptom of various illnesses. I'm not sure if you know this but a lot of theraputic work does focus on solving external problems. You mi…
To me it seems happiness is basically a big AND-expression of fulfilled needs. If someone is lonely they need community, if someone is scared they need safety, if they are malnourished they need food etc.
Re: New study finds psilocybin greatly and quickly relieves depression
#148Earlier quoted context omitted.
What do you mean? Can you elaborate?
I did not find my psilocybin trip pleasurable. With the exceptions of 1) micro-dosers and 2) those that seek mind altering experiences as a lifestyle ... the studies have reinforced my personal experience: once seems to be enough. (Edited to make clear my opinion vs facts)
Caffeine is a mind altering experience. Eating too much sugar is a mind altering experience. Drinking alcohol is a mind altering experience. I have had extremely pleasant and also terrifying psilocybin trips. They have all been constructive experiences for me.
Re: New study finds psilocybin greatly and quickly relieves depression
#149Earlier quoted context omitted.
I did not find my psilocybin trip pleasurable. With the exceptions of 1) micro-dosers and 2) those that seek mind altering experiences as a lifestyle ... the studies have reinforced my personal experience: once seems to be enough. (Edited to make clear my opinion vs facts)
I feel that you are posting some very irresponsible things in the comments here in a very authoritative tone. I would kindly invite you to refrain from doing so, since I disagree strongly with your various assertions. Perhaps you can offer your views as your personal perspective rather than objective truth. Caffeine is a mind altering experience. Eating too much sugar is a mind altering experience. Drinking alcohol i…