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How the Coronavirus Hacks the Immune System

newyorker.com

101–104 of 104 posts

Re: How the Coronavirus Hacks the Immune System

#101
post #59

Earlier quoted context omitted.

extremely naive, dumb questeion: could cancer cells stem from some errant mutation of B cells? this might help explain why cancer cells grow uncontrollably and also escape detection by the immune system.

https://en.wikipedia.org/wiki/B-cell_lymphoma

thanks for sharing this link. is it possible that other cancer cells are further downstream mutations of B cells?

Re: How the Coronavirus Hacks the Immune System

#102
post #4
post #2

Many paragraphs into the article and I still don’t know what important discovery or observation has been made

This kind of reporting interleaved with storytelling in a really weird voice is frustrating. Why do journalists write like this? What purpose does this word salad serve? I can do this myself! "On a bald September day, a man walks into a barber shop, languishes at the occupied seats, and voilà, while sensing upcoming bowel movements, he discovers the next great theory of economics."

It's because students are being admitted to universities (including ivy league ones) based on informal political quotas. Once inside they don't learn per se but are indoctrinated with the virtues of diversity and tolerance. Nobody should be amazed that when they graduate, they write like a 12 year old: that was the whole point.

Re: How the Coronavirus Hacks the Immune System

#103
post #62

Earlier quoted context omitted.

> could cancer cells stem from some errant mutation of B cells? That is exactly how lymphomas originate.

is it possible that other cancer cells are further downstream mutations of B cells? thanks for sharing. sorry if these are dumb questions.

It is unlikely, given that B cells are already differentiated. This means that they are unable to change into another cell type.

Re: How the Coronavirus Hacks the Immune System

#104

Earlier quoted context omitted.

is it possible that other cancer cells are further downstream mutations of B cells? thanks for sharing. sorry if these are dumb questions.

It is unlikely, given that B cells are already differentiated. This means that they are unable to change into another cell type.

thanks for the clarification.

phrased another way: could the same process that spawns these legions of B cells also inadvertently spawn cancer cells?

related: healthy cells exhibit properties that allow them to go ignored by the immune system, similar to a VIP pass for bypassing security at a basketball game. is this right? if yes, what are the minimal properties that constitute this cellular VIP pass?

thanks for your help.

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