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Intermittent fasting increases hippocampal neurogenesis in mice

pubmed.ncbi.nlm.nih.gov

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Re: Intermittent fasting increases hippocampal neurogenesis in mice

#41

I fast pretty easily from 6pm to noon the next day. So I would be getting an awesome 18 hour fast daily however I have coffee with milk at 8am. Am I cancelling out those last 4 hours? I hate black coffee so I’m not sure what I could do.

That’s what I did for a long time. But somehow it didn’t feel right. I then switched to 4pm to 8am. Works way better for me now

Re: Intermittent fasting increases hippocampal neurogenesis in mice

#42
post #37

I fast pretty easily from 6pm to noon the next day. So I would be getting an awesome 18 hour fast daily however I have coffee with milk at 8am. Am I cancelling out those last 4 hours? I hate black coffee so I’m not sure what I could do.

Switch when you eat. So 8am to 2pm or 4pm eating time.

That’s certainly an idea. The nice thing now is that it’s effortless.

I don’t feel like eating after dinner and I don’t feel hungry in the morning.

You’d think there would be something calorie free to make coffee taste good.

Re: Intermittent fasting increases hippocampal neurogenesis in mice

#43

I fast pretty easily from 6pm to noon the next day. So I would be getting an awesome 18 hour fast daily however I have coffee with milk at 8am. Am I cancelling out those last 4 hours? I hate black coffee so I’m not sure what I could do.

lol, exactly same diet with the same coffee problem here. I'm constantly told that "coffee is fine" whenever I ask. But milk is still food and not a "drink" so switching to black would be the only acceptable solution. sigh.

Re: Intermittent fasting increases hippocampal neurogenesis in mice

#44

For anyone wondering: > Adult hippocampal neurogenesis is a process that describes the generation of new functional DGCs from adult neural stem cells through the amplification of intermediate progenitors and neuroblasts, as well as the integration of these new neurons into the existing neural circuits. Source: https://www.nature.com/articles/s41380-018-0036-2#:~:text=Ad... .

Is this a breaking change or backwards compatible?

Re: Intermittent fasting increases hippocampal neurogenesis in mice

#45
post #41

I fast pretty easily from 6pm to noon the next day. So I would be getting an awesome 18 hour fast daily however I have coffee with milk at 8am. Am I cancelling out those last 4 hours? I hate black coffee so I’m not sure what I could do.

That’s what I did for a long time. But somehow it didn’t feel right. I then switched to 4pm to 8am. Works way better for me now

So early dinner? And then a big breakfast?

It’s hard with a family though if they’re on different schedules.

Re: Intermittent fasting increases hippocampal neurogenesis in mice

#46
It makes sense that food deprivation stimulates hippocampal neurogenesis, because in the absence of food, a mammal has to go to new locations to find new food sources. That requires navigation and memory mapping, both of which are core functions of the hippocampus.

https://journals.physiology.org/doi/full/10.1152/jn.00005.20...

Re: Intermittent fasting increases hippocampal neurogenesis in mice

#48
Interesting and lines up with other brain development factors found in human fasting (https://cdnsciencepub.com/doi/abs/10.1139/apnm-2014-0290).

I often read these threads about fasting/intermittent fasting on HN and see a lot of nitpicking about flaws in the study.

Given that almost all studies tend to fall between "no effect" or "clear positive effect" of fasting on health, do we have enough evidence to say "fasting is good for your health?" I still believe there's value in further research to nail down exactly how and how much, but curious if we can make the overall statement confidently.

Re: Intermittent fasting increases hippocampal neurogenesis in mice

#49

I fast pretty easily from 6pm to noon the next day. So I would be getting an awesome 18 hour fast daily however I have coffee with milk at 8am. Am I cancelling out those last 4 hours? I hate black coffee so I’m not sure what I could do.

Maybe. I think in the study the rats were fully fasted, so you’re into unknown territory as far as the study goes. But I also assume you’re not a rat, so that’s not exactly the biggest difference.

There are lots of definitions of fasting and it’s not perfectly understood which consequences line up with which behaviors.

It’s pretty clear things are different once you break down the different ideas of “fast” and build it back up. In a dry fast, nothing enters your body except air. Now switch to a water fast and your stomach and kidneys are going to start doing something with that water. Have some coffee and now your liver is processing that caffeine and other chemicals. Add some calories (milk) and more organs are doing more. And then once you get past 500 calories in a day, you’re not really fasting by just about any definition.

So your coffee is doing something, the milk is doing something, but I don’t think it’s perfectly clear what happens at each threshold.

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