Intermittent fasting increases hippocampal neurogenesis in mice

#1

Post by voisin » Sat, Oct 31, 2020, 4:17 PM UTC

Intermittent fasting increases hippocampal neurogenesis in mice
pubmed.ncbi.nlm.nih.gov

Re: Intermittent fasting increases hippocampal neurogenesis in mice

#2

Post by bitxbitxbitcoin » Sat, Oct 31, 2020, 4:31 PM UTC

I don't know enough about neurobiology to fully understand the graphs beyond the general conclusion in the title.

Could someone explain what this tells us about 16 hour vs 24 hour intermittent fasting? Is one "better" than the other?

Re: Intermittent fasting increases hippocampal neurogenesis in mice

#3

Post by frisco » Sat, Oct 31, 2020, 4:34 PM UTC

bitxbitxbitcoin wrote: post #2

I don't know enough about neurobiology to fully understand the graphs beyond the general conclusion in the title. Could someone explain what this tells us about 16 hour vs 24 hour intermittent fasting? Is one "better" than the other?

Per the figures, it looks like 16 hours had the largest effect, even larger than 24 hour fasts. But this is mouse data and should all be taken with a huge grain of salt.

Re: Intermittent fasting increases hippocampal neurogenesis in mice

#4

Post by geforce » Sat, Oct 31, 2020, 4:36 PM UTC

A bit unrelated, but made me remember this study: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2995774/

The effects of fasting on the human body are... fastinating! (Sorry!)

Re: Intermittent fasting increases hippocampal neurogenesis in mice

#5

Post by netfl0 » Sat, Oct 31, 2020, 4:37 PM UTC

I feel like the term intermittent fasting is used by many folks to mean different things. It would be nice if there were more precise terminology here so we could communicate more clearly.

Re: Intermittent fasting increases hippocampal neurogenesis in mice

#6

Post by diydsp » Sat, Oct 31, 2020, 4:44 PM UTC

netfl0 wrote: post #5

I feel like the term intermittent fasting is used by many folks to mean different things. It would be nice if there were more precise terminology here so we could communicate more clearly.

From the fine article:

>We evaluated the impact of 3 months of IF (12, 16, and 24 hr of food deprivation on a daily basis)

Re: Intermittent fasting increases hippocampal neurogenesis in mice

#7

Post by thangalin » Sat, Oct 31, 2020, 4:47 PM UTC

frisco wrote: post #3

bitxbitxbitcoin wrote: post #2

I don't know enough about neurobiology to fully understand the graphs beyond the general conclusion in the title. Could someone explain what this tells us about 16 hour vs 24 hour intermittent fasting? Is one "better" than the other?

Per the figures, it looks like 16 hours had the largest effect, even larger than 24 hour fasts. But this is mouse data and should all be taken with a huge grain of salt.

> taken with a huge grain of salt

But only once every 16 hours, apparently.

Re: Intermittent fasting increases hippocampal neurogenesis in mice

#8

Post by chiefalchemist » Sat, Oct 31, 2020, 4:48 PM UTC

Can we get the title updated? This is for rodents.

Re: Intermittent fasting increases hippocampal neurogenesis in mice

#9

Post by Nabati » Sat, Oct 31, 2020, 4:48 PM UTC

16 hours for a mouse is probably equivalent to fasting multiple days for humans.

Re: Intermittent fasting increases hippocampal neurogenesis in mice

#10

Post by auston » Sat, Oct 31, 2020, 4:50 PM UTC

Nabati wrote: post #9

16 hours for a mouse is probably equivalent to fasting multiple days for humans.

This! Mice are not quite the same as humans.