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Intermittent fasting from dawn to sunset induces anticancer response

pubmed.ncbi.nlm.nih.gov

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Re: Intermittent fasting from dawn to sunset induces anticancer response

#251

Post by hutzlibu »

lotsofpulp wrote: post #64
ab8 wrote: post #49

Earlier quoted context omitted.

The more you are used to eating in an average meal, the longer it takes to feel "full".

Also, it takes time for the chemical reactions in your body to tell you you are full, so if you eat a little bit, and stop for 15 min, you might very well find that you are full. However, once the taste buds are firing, it’s pretty hard to stop eating mid meal. One way is to take a little bit of food away from all the other food, eat it, and then force yourself to sit there while your blood sugar catches up to tell y…

One of the reasons, why it is a good idea to eat slowly.

Re: Intermittent fasting from dawn to sunset induces anticancer response

#252

Post by andi999 »

marketingPro wrote: post #33
haram_masala wrote: post #19

No control group, and n=14. This study says nothing.

Generally it's good to be skeptical but this- "We found a significant fold increase in the levels of several tumor suppressor and DNA repair gene protein products (GP)s at the end of 4th week during 4-week intermittent fasting (CALU, INTS6, KIT, CROCC, PIGR), and 1 week after 4-week intermittent fasting (CALU, CALR, IGFBP4, SEMA4B) compared with the levels before 4-week intermittent fasting." But why would this sudde…

Well, could be a different thing altogether. This was probably done in Ramadan (the no-drinking thing, and the researches from Turkey as I saw in a different comment). So there would also be no smoking allowed for 14h per day. Maybe this has an effect.

Re: Intermittent fasting from dawn to sunset induces anticancer response

#253

Post by baxtr »

JacKTrocinskI wrote: post #173

I don’t think you should be looking at studies when it comes to how you eat, you should be focusing on how you feel, observing your own body and possibly talking to a doctor. I had a really big problem with acid reflux a while back after I stopped drinking alcohol. I visited many gastrologists and most of them offered little to no help, most only prescribed me drugs which was in my opinion not a solution. I finally m…

Just because we have slightly different bodies doesn’t mean we can’t do science. We need controls etc, but it’s doable even if it’s very hard with complex biological systems.

BTW: what did you eat during the time? It seems like you couldn’t eat a lot of you leave out fruits and most meat

Re: Intermittent fasting from dawn to sunset induces anticancer response

#254

Post by jack_pp »

kashif wrote: post #238
JacKTrocinskI wrote: post #173

I don’t think you should be looking at studies when it comes to how you eat, you should be focusing on how you feel, observing your own body and possibly talking to a doctor. I had a really big problem with acid reflux a while back after I stopped drinking alcohol. I visited many gastrologists and most of them offered little to no help, most only prescribed me drugs which was in my opinion not a solution. I finally m…

This is really bad advice. Its important to do actual science and not run on anecdotes.

What is actual science?

Are studies asking people how many times they eat food X per week and correlating on that information science?

The study in the link has a sample size of 14, is that ” actual” science?

Re: Intermittent fasting from dawn to sunset induces anticancer response

#256

Post by shock »

ravenstine wrote: post #30
voisin wrote: post #17

Earlier quoted context omitted.

From what I understand, autophagy doesn’t start until 18 hours and doesn’t peak until 72 hours.

I've never heard of that 18 hour rule. It's funny because I've read a lot about fasting, but this is news to me, and it seems like this is reported from multiple sources. But I can't seem to find any authoritative references.

The Japanese researcher that got a Nobel Prize for discovering the autophagy mechanisms has a course on edx. Doesn't get much more authoritative than that.

Re: Intermittent fasting from dawn to sunset induces anticancer response

#257

Post by Broken_Hippo »

d--b wrote: post #122

All the muslim world does 4-week intermittent fasting every year. That'd make it easy to test the asumption of the paper on a large scale population

1. Some folks cheat. 2. Some, who you would think are otherwise healthy, cannot fast (I have a friend that found out he cannot fast. He was instead hospitalized). 3. The severity of the fast depends on the time of year the fast falls and where in the world you are. Right now, it is certainly worse in Norway (where the days very long in June) than it is in the southern hemisphere, where the days have their winter lengths.

The last two can be somewhat accounted for (and already are: Folks that can't fast are exempt and special rules for places that get midnight sun). We can't really control for the first one, especially with real cultural taboo against breaking the fast during the day.

Re: Intermittent fasting from dawn to sunset induces anticancer response

#258

Post by redis_mlc »

anigbrowl wrote: post #126
Barrin92 wrote: post #102

Earlier quoted context omitted.

>It's much easier to tell someone that they can eat as much as they want, but only between 6-8pm (one meal a day). If eating is part of your social or work life as it is for most people then not really. Or you're going to sit there sipping water while your family or your colleagues eat or have drinks which is miserable

Most Muslims seem to manage it annually.

Not really. They gorge themselves at night, so unlimited calories basically.

Re: Intermittent fasting from dawn to sunset induces anticancer response

#259

Post by ploum »

kimi wrote: post #222
fragsworth wrote: post #212

Earlier quoted context omitted.

If you're referring to Ramadan, I don't believe that's the same thing, because it is two meals a day, spaced apart significantly, and only lasts a month. I also question religious devotees adherence to their religion. There are no stats on it and it is impossible to measure... Perhaps a significant number of them secretly cheat.

This study is exactly Ramadan, by design (but it does not say so in the title). In fact one of the recruiting rules was "2) Subjects who plan to fast during the religious month of Ramadan" and therefore "All subjects fasted for more than 14 h daily for 29 days beginning from May 06, 2019, until June 03, 2019". See full text https://www.nature.com/articles/s41598-020-73767-w

That raised my suspicion. In an era of politic-driven pseudo-scientific paper, I was wondering :

1. Why ramadan is not explicitely told in the title. 2. Why using "dawn to sunset" which is not helpful at all to make generalisation (scientists usually have a clock). 3. Why the diet during the night is not explicited (at least in the abstract). 4. Why this would have different results if the diet is during the night or during the day.

All of this makes me suspicious that this is a kind of retro-science propaganda to make Ramadan looks healthy and justify the religion.

I maybe wrong but the abstract raises too many flags to not care about this hypothesis.

Re: Intermittent fasting from dawn to sunset induces anticancer response

#260

Post by [deleted] »

Markoff wrote: post #192
Melting_Harps wrote: post #96

I've been doing a 16-20 hour fast since the lockdown and WFH, and to be honest I saw a significant decrease in my overall anxiety as a result. Anxiety I often offset with significant amounts of CBD (a $100/month expense). And while there are drawbacks, I can't bench press 215lbs anymore, the overall benefits have been pretty significant that I will keep doing it. My weight was pretty erratic, given the high stress lo…

Is it really fasting though? That's having big lunch and just skipping dinner. Many people do this often unintentionally without calling it fasting at all. You should move at least to 36-40 hours, although even that I don't find particularly special.

[deleted]
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