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Vaccine hopes rise as Oxford jab prompts immune response among old and young

reuters.com

361–370 of 712 posts

Re: Vaccine hopes rise as Oxford jab prompts immune response among old and young

#361
post #344

I'm in the trial. Here's the participant information sheet, in case anyone's curious: https://drive.google.com/file/d/1WB5QPmECchlThnem9wcX0PDaKQW...

Thank you very much for sharing this. >Until now, this vaccine has only been tested on laboratory mice and other animal species and this is the first time that the vaccine will be given to humans. Is it possible to know which species those are?

Don’t personally know but usually it’s monkeys.

Re: Vaccine hopes rise as Oxford jab prompts immune response among old and young

#362
post #349

I'm in the trial. Here's the participant information sheet, in case anyone's curious: https://drive.google.com/file/d/1WB5QPmECchlThnem9wcX0PDaKQW...

Considering all the excluded groups on the trial (page 3, kids, 55+, obese, weak immune system, a lot more), it's a lot of exclusions, how does one get from results on a study like this to declaring the vaccine safe for general use?

Generally speaking, experimental drug trials are run first on healthy groups and then in at-risk groups (old, young, those with co-morbidities). From the article, my guess is that they are expediting the sensitive groups trials, but unfortunately there's a lack of technical detail.

Source: My partner is an infectious disease specialist and we talk about this pretty much daily because I'm so curious.

Re: Vaccine hopes rise as Oxford jab prompts immune response among old and young

#363
post #286

Earlier quoted context omitted.

Because the government hasn't been able to do anything right for 270 years, why do you think they're suddenly gonna wake up a figure out mass manufacturing? We can't educate our kids at an acceptable level without billions of dollars being donated on top of all the tax collected, we can't figure out how to make medicare work responsibly despite literally being able to control costs, what do you think makes drug manuf…

In the US, one party has dedicated itself to making sure the government is dysfunctional for a _long_ time so that it can run on the platform that government doesn’t work and we should privatize everything. This is not a fact of nature, it’s a willful decision. For example, the US used to be a leader in education. The thing that changed since then is one party started defunding education and moving that money to priv…

If your statement was true, Chicago and California would be bastions of government efficiency and capability. Instead we see both Republican and Democratic cities do terribly on most measures, and those cities that generally prosper have very little to do with who is in control other than it not being a single party and they have the right conditions for job growth.

School funding happens at the state level too, not just the federal grants.

Re: Vaccine hopes rise as Oxford jab prompts immune response among old and young

#364
post #349

I'm in the trial. Here's the participant information sheet, in case anyone's curious: https://drive.google.com/file/d/1WB5QPmECchlThnem9wcX0PDaKQW...

Considering all the excluded groups on the trial (page 3, kids, 55+, obese, weak immune system, a lot more), it's a lot of exclusions, how does one get from results on a study like this to declaring the vaccine safe for general use?

"The purpose of this study is to text a new vaccine against COVID-19 in healthy volunteers.

So I am assuming this is the control group.

Re: Vaccine hopes rise as Oxford jab prompts immune response among old and young

#365

Earlier quoted context omitted.

SARS-CoV-2 relies on superspreading much more than e.g. the common cold. When you hear, for example, that each patient in a given area infects 1.2 other people on average, this doesn't mean that everyone spreads it to one or two people. It means that out of 10 infectious patients, 9 patients don't spread it to anyone else and the tenth patient spreads it to a dozen people at once. Because of this high dispersion rate…

I'm not saying don't give it to them as well, just do the vulnerable people first. At least then we stand a chance of getting the economy back on its feet.

"Just do the vulnerable people first" has the significant advantage of being easy to explain and implement, but it does not maximize the speed of economic recovery.

For instance, I'm a vulnerable person because of preexisting conditions, so I'll likely be offered a vaccine relatively soon after approval. But that won't have a large impact on economic recovery: I'm in the home office in a single-person household and don't have any care obligations, so I'm at a comparatively low risk anyway. And I won't change my current behavior until the disease is fully gone anyway.

Re: Vaccine hopes rise as Oxford jab prompts immune response among old and young

#366

I'm in the trial. Here's the participant information sheet, in case anyone's curious: https://drive.google.com/file/d/1WB5QPmECchlThnem9wcX0PDaKQW...

Are you given any monetary compensation or compensation at all for joining the trial?

From TFPDF:

>You will be compensated for your time, the inconvenience of having blood tests and procedures, and your travel expenses. The total amount compensated will be approximately £235 - £625 depending on the exact number of visits and whether any repeat or additional visits are necessary.

Re: Vaccine hopes rise as Oxford jab prompts immune response among old and young

#367
post #268

Earlier quoted context omitted.

Not when it's a monopoly. That means the company gets to exploit the results of the research for their own profit, without any competition to keep prices reasonable. Non-exclusive deals are fine. Exclusive ones are not.

Look, I understand the frustration but they're not going to set this price. This thing is way bigger than this company and even the entire pharmaceutical industry. This is a global crisis. Many governments have proven that they will put the public's need over these companies need. They've broken patents and pressured companies before and they will obviously do it again. There are more governments in the world than th…

I'm not a public policy, legal, or economics expert, but I certainly favor treating this as a one-off. If a legal monopoly is the most expedient way to get us back to normal, so be it, and if fears of price gouging are a concern let congress or the executive or whomever cap the price. Once things get back to normal we can litigate the monopoly issue.

Re: Vaccine hopes rise as Oxford jab prompts immune response among old and young

#368
post #116

Good news for US BigPharma Merck holding the Oxford patents, while public funding has paid for its research: https://archive.is/aGUJd

Who cares. I'd gladly give this company a couple of billion if it means they can get us back to normal. Oxford develops the vaccine with public money. We also, god willing, need to manufacture billions of them and transport them around the globe. For that manufacturing, give me a solid existing multinational with a proven manufacturing record and base please, not some non-profit startup.

[deleted]

Re: Vaccine hopes rise as Oxford jab prompts immune response among old and young

#369
post #349

I'm in the trial. Here's the participant information sheet, in case anyone's curious: https://drive.google.com/file/d/1WB5QPmECchlThnem9wcX0PDaKQW...

Considering all the excluded groups on the trial (page 3, kids, 55+, obese, weak immune system, a lot more), it's a lot of exclusions, how does one get from results on a study like this to declaring the vaccine safe for general use?

Why would tabloid glamour models be excluded?

Re: Vaccine hopes rise as Oxford jab prompts immune response among old and young

#370
post #344

I'm in the trial. Here's the participant information sheet, in case anyone's curious: https://drive.google.com/file/d/1WB5QPmECchlThnem9wcX0PDaKQW...

Thank you very much for sharing this. >Until now, this vaccine has only been tested on laboratory mice and other animal species and this is the first time that the vaccine will be given to humans. Is it possible to know which species those are?

It has been tested on rhesus macaque monkeys.
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