I'm in the trial. It's really exciting, not least because form a purely selfish point of view, I might be immune already! ...or not. But it's exciting either way!
AMA?
Vaccine hopes rise as Oxford jab prompts immune response among old and young
341–350 of 712 posts
Re: Vaccine hopes rise as Oxford jab prompts immune response among old and young
#342Earlier quoted context omitted.
I think you might be surprised. The government knows that this is the silver bullet they need to rescue the economy from oblivion. I’m expecting that once this thing is ready there’ll be a logistical effort for the history books to roll it out. See what they can do with the military involved, like the nightingales.
Sad to say, given how testing, lockdown, etc. has proceeded, I'm losing confidence that most western governments are capable of any "logistical efforts for the history books" at this point. I heard a lot of bluster about testing here in Ontario in the spring, but here we are in the fall with rationing of tests again.
I am glad that western governments are not capable of lockdown.
Re: Vaccine hopes rise as Oxford jab prompts immune response among old and young
#343Earlier quoted context omitted.
Overly cautious about the herd immunity stuff here. We're not going to eliminate the virus completely. That's a given, we should stop aiming for that. If we get to a point where there's a stable number of daily deaths then we're good. (like we have for literally every single fatal illness.)
> (like we have for literally every single fatal illness) Smallpox. And if you consider within the borders of a given country, a dozen others (polio, measles, mumps, rubella, chickenpox).
None of those are a common type of Flu, which we've never been able to cure, though.
Re: Vaccine hopes rise as Oxford jab prompts immune response among old and young
#344I'm in the trial. Here's the participant information sheet, in case anyone's curious: https://drive.google.com/file/d/1WB5QPmECchlThnem9wcX0PDaKQW...
Thank you very much for sharing this.
>Until now, this vaccine has only been tested on laboratory mice and other animal species and this is the first time that the vaccine will be given to humans.
Is it possible to know which species those are?
Re: Vaccine hopes rise as Oxford jab prompts immune response among old and young
#345Earlier quoted context omitted.
Given the low fatality rate for COVID, wouldn't you just want to concentrate vaccination on those most at risk? i.e. the elderly, people with underlying conditions etc. You don't need to eradicate the virus, just stop it affecting the most vulnerable. Everybody else can then carry on as normal (albeit with a slight chance of getting a nasty flu-like illness).
Even if we vaccinate every vulnerable group, no vaccine has 100% success rate. That's why every vaccine we ever had relied on a huge majority of people having it to prevent the virus from reaching those whose vaccine failed. Not to mention that we already know about long term side effects that have nothing to do with a specific age group, and that there's a chance of re-infection.
Sure but it would reduce the number of deaths by a lot.
If we just vaccinated 65+ year olds, we'd cut deaths by 80X%, where X is the effectivelness of the vaccine. Even if the vaccine was only 80% effective, that's still 65% reduction.
Add in people with dangerous conditions, heart conditions, cancer, morbidly obese, etc., and you could probably knock it down further.
And as the percent of the population with immunity rises, the spread will slow quite a bit.
We don't need heard immunity to open back up.
Re: Vaccine hopes rise as Oxford jab prompts immune response among old and young
#346Earlier quoted context omitted.
Let's see, because the vaccination probably requires two shots per person with probably 6-8 months in between, so it will take time...
Where did you read 6-8 months between? I’ve just seen the timespan between shots be listed as 1 month almost everywhere.
I was basing the comment in some other vaccines - Sorry I did not state it. I hope I'm wrong and it's much shorter time :)
Can you also share some of those sources you mention? Thanks!
Re: Vaccine hopes rise as Oxford jab prompts immune response among old and young
#347Earlier quoted context omitted.
> (like we have for literally every single fatal illness) Smallpox. And if you consider within the borders of a given country, a dozen others (polio, measles, mumps, rubella, chickenpox).
Which countries have eliminated the latter 4? I would consider an illness "eradicated" if the vaccine is no longer regularly given. At least 10 years ago (when I was in the field), MMR and Chickenpox vaccines were still regularly administered in the US.
> I would consider an illness "eradicated" if the vaccine is no longer regularly given
Fair enough. I would consider a virus eradicated when the general population gives zero thought to it, and effectively no one dies from it. Doesn't meet the strict medical definition, but I thought the description of "If we get to a point where there's a stable number of daily deaths then we're good" was overly pessimistic.
Re: Vaccine hopes rise as Oxford jab prompts immune response among old and young
#348I'm in the trial. It's really exciting, not least because form a purely selfish point of view, I might be immune already! ...or not. But it's exciting either way! AMA?
What if something goes horribly wrong and the vaccine trial causes unwanted side effects? Why risk it, what are they paying you?
Re: Vaccine hopes rise as Oxford jab prompts immune response among old and young
#349I'm in the trial. Here's the participant information sheet, in case anyone's curious: https://drive.google.com/file/d/1WB5QPmECchlThnem9wcX0PDaKQW...
Considering all the excluded groups on the trial (page 3, kids, 55+, obese, weak immune system, a lot more), it's a lot of exclusions, how does one get from results on a study like this to declaring the vaccine safe for general use?
Re: Vaccine hopes rise as Oxford jab prompts immune response among old and young
#350I'm in the trial. It's really exciting, not least because form a purely selfish point of view, I might be immune already! ...or not. But it's exciting either way! AMA?
What if something goes horribly wrong and the vaccine trial causes unwanted side effects? Why risk it, what are they paying you?
I'm receiving no money for my participation. I wasn't in the initial Phase I trial, a few hundred people had already received the vaccine before me with no unexpected side effects.
I guess I'm risking it because someone has to. Vaccine trials are incredibly safe and highly regulated. In reality, the worst-case was that it didn't work rather than my head exploding.