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Cognitive deficits in people who have recovered from Covid-19

medrxiv.org

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Re: Cognitive deficits in people who have recovered from Covid-19

#2
From the conclusion:

"The scale of the observed deficits was not insubstantial; the 0.57 SD global composite score reduction for the hospitalised with ventilator sub-group was equivalent to the average 10-year decline in global performance between the ages of 20 to 70 within this dataset. It was larger than the mean deficit of 512 people who indicated they had previously suffered a stroke (-0.40SDs) and the 1016 who reported learning disabilities (-0.49SDs). For comparison, in a classic intelligence test, 0.57 SDs equates to an 8.5-point difference in IQ."

Re: Cognitive deficits in people who have recovered from Covid-19

#3
By no means do I want to detract from the severity of covid infections, but a very important question to answer would be "what's the effect of psychotrauma resulting from illness and hospitalization on cognitive function"

I feel that my own cognitive functions have declined as well during the pandemic, due to stress and uncertainty alone. I haven't been infected, mind you.

Re: Cognitive deficits in people who have recovered from Covid-19

#4
post #2

From the conclusion: "The scale of the observed deficits was not insubstantial; the 0.57 SD global composite score reduction for the hospitalised with ventilator sub-group was equivalent to the average 10-year decline in global performance between the ages of 20 to 70 within this dataset. It was larger than the mean deficit of 512 people who indicated they had previously suffered a stroke (-0.40SDs) and the 1016 who…

> the hospitalised with ventilator sub-group

So this affects almost nobody then, and is probably caused by the sedatives, immobilization and ventilator organ damage, aside from corona.

Re: Cognitive deficits in people who have recovered from Covid-19

#6

By no means do I want to detract from the severity of covid infections, but a very important question to answer would be "what's the effect of psychotrauma resulting from illness and hospitalization on cognitive function" I feel that my own cognitive functions have declined as well during the pandemic, due to stress and uncertainty alone. I haven't been infected, mind you.

> "what's the effect of psychotrauma resulting from illness and hospitalization on cognitive function"

Ventilators are extremely physically traumatic - those patients are considered to be the sickest in any hospital.

Re: Cognitive deficits in people who have recovered from Covid-19

#8

By no means do I want to detract from the severity of covid infections, but a very important question to answer would be "what's the effect of psychotrauma resulting from illness and hospitalization on cognitive function" I feel that my own cognitive functions have declined as well during the pandemic, due to stress and uncertainty alone. I haven't been infected, mind you.

> "what's the effect of psychotrauma resulting from illness and hospitalization on cognitive function" Ventilators are extremely physically traumatic - those patients are considered to be the sickest in any hospital.

It must be hell to have a bunch of suited figures tell you "we're putting you to sleep, hope to see you on the other side"... and then wake up intubated.

Re: Cognitive deficits in people who have recovered from Covid-19

#9
post #2

From the conclusion: "The scale of the observed deficits was not insubstantial; the 0.57 SD global composite score reduction for the hospitalised with ventilator sub-group was equivalent to the average 10-year decline in global performance between the ages of 20 to 70 within this dataset. It was larger than the mean deficit of 512 people who indicated they had previously suffered a stroke (-0.40SDs) and the 1016 who…

> the hospitalised with ventilator sub-group So this affects almost nobody then, and is probably caused by the sedatives, immobilization and ventilator organ damage, aside from corona.

Well, the fact that someone was uable to breathe on their own also suggests that the virus may have caused a lack of oxygen to the brain. In such circumstances brain damage is quite likely, and then the disease would indeed be the cause.

Fortunately, the group of people that end up on ventilators is not really that large, and I can imagine minor brain damage would still be preferable to death in many of those cases.

As a sibling commented, theeffects that won't start to manifest until a year or two has passed are more worrying. There's simply so much we don't know about this virus yet.

Re: Cognitive deficits in people who have recovered from Covid-19

#10
post #2

From the conclusion: "The scale of the observed deficits was not insubstantial; the 0.57 SD global composite score reduction for the hospitalised with ventilator sub-group was equivalent to the average 10-year decline in global performance between the ages of 20 to 70 within this dataset. It was larger than the mean deficit of 512 people who indicated they had previously suffered a stroke (-0.40SDs) and the 1016 who…

> the hospitalised with ventilator sub-group So this affects almost nobody then, and is probably caused by the sedatives, immobilization and ventilator organ damage, aside from corona.

Not sure why you’re getting downvoted - here’s a page about post-intensive care syndrome, on the website of the society for critical care medicine, that’s concordant with what you said: https://www.sccm.org/MyICUCare/THRIVE/Post-intensive-Care-Sy...
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