Earlier quoted context omitted.
Personally I think this would be unfortunate as I don't think JavaScript is the path forward, but computers have always existed to run software (d'oh), which mean the natural selection will obviously make this happen if there is a market advantage. However I see all high performance web computing moving to WASM and JavaScipt will exist just as the glue to tie it together. Adding hardware support for this is naive and…
maybe this will lead to the revival of Transmeta-like architectures? I always had a soft spot for reprogrammable microcode.
Because of this I find WASM to be the best direction yet for a "universal ISA" as it's very feasible to translate to most strange new radical architecture (like EDGE, Prodigy, etc). (Introducing a new ISA is almost impossible due to the cost of porting the world. RISC-V might be the last to succeed).