How Much Vitamin D Is Too Much? A Case Report and Review of the Literature
pubmed.ncbi.nlm.nih.gov
How Much Vitamin D Is Too Much? A Case Report and Review of the Literature
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Re: How Much Vitamin D Is Too Much? A Case Report and Review of the Literature
#2So, on average, 200ish times the recommended daily dose? No wonder she had problems.
Re: How Much Vitamin D Is Too Much? A Case Report and Review of the Literature
#3So, on average, 200ish times the recommended daily dose? No wonder she had problems.
Agreed, but her problems resolved within 6 months and VitD returned to normal within 18. Quite a difference from the doctor here on HN that has been claiming irreversible issues from taking doses far below what this lady took.
Re: How Much Vitamin D Is Too Much? A Case Report and Review of the Literature
#4So, on average, 200ish times the recommended daily dose? No wonder she had problems.
Agreed, but her problems resolved within 6 months and VitD returned to normal within 18. Quite a difference from the doctor here on HN that has been claiming irreversible issues from taking doses far below what this lady took.
Hard to draw many conclusions from a sample size of 1, other than that taking megadoses is a bad idea.
Re: How Much Vitamin D Is Too Much? A Case Report and Review of the Literature
#5The title doesn’t match the abstract. This isn’t a study of the tolerable upper limit of Vitamin D intake. It’s a case report of a single individual who was taking astronomical doses of Vitamin D with disastrous consequences.
It’s certainly possible to take too much vitamin D without coming anywhere near the silly doses this person was consuming.
Anyone taking aggressive vitamin D doses should invest in a vitamin D test after 6-12 months. If you find your serum results approaching the upper end of the reference range, reduce intake slightly. There are no known benefits to excessive vitamin D serum levels, but there are documented health downsides.
If you find yourself reading pop-science articles with unbridled enthusiasm for megadosing vitamins, you’re probably not reading scientifically accurate health advice. Supplementing with moderate doses is fine, but megadosing anything is almost always flimsy pseudoscience.
Re: How Much Vitamin D Is Too Much? A Case Report and Review of the Literature
#6Taking 130,000UI per day for 20 months is insane. Most of the over the counter doses are ~ 5000UI.
I'm curious, as to what was the patients diet like? Vit D is a fat soluble vitamin and its my understanding that one needs to eat healthy fats for it to be absorbed by the body.
Re: How Much Vitamin D Is Too Much? A Case Report and Review of the Literature
#7So, on average, 200ish times the recommended daily dose? No wonder she had problems.
I think 130 times recommended. Or perhaps only 30 times what should be recommend.
It's thought the old recommended dose is to low for some people or some situations. Which is why they really want to push it up as much as possible for all because it will save lives.
Hence these studies. I'm doing 1000UI daily given current data and covid-19.
Re: How Much Vitamin D Is Too Much? A Case Report and Review of the Literature
#8"The patient had been assuming very high dose of cholecalciferol since 20 months (cumulative 78,000,000UI, mean daily 130,000UI), as indicated by a non-conventional protocol for multiple sclerosis."
"This case confirms that vitamin D intoxication is possible albeit with a really high dose."
This is a truly insane dosage but all this case says is that however created this protocol is dangerously incompetent.
Re: How Much Vitamin D Is Too Much? A Case Report and Review of the Literature
#9So, on average, 200ish times the recommended daily dose? No wonder she had problems.
Agreed, but her problems resolved within 6 months and VitD returned to normal within 18. Quite a difference from the doctor here on HN that has been claiming irreversible issues from taking doses far below what this lady took.
Don’t mistake the remission of serious, life-threatening anomalies in this one patient as evidence that no long-term damage was done.
In these cases, the doctors aren’t giving the patient a clean bill of health across all parameters. They’re just confirming that the immediately life threatening issues are no longer an imminent danger to the patient. It’s entirely likely that the patient suffered more insidious, long-term health consequences that aren’t immediately obvious.
It should also go without saying that the excessive vitamin D doses didn’t do her any favors. The “more is better” approach to vitamins in the alternative medicine community really needs to stop.
Re: How Much Vitamin D Is Too Much? A Case Report and Review of the Literature
#10"The patient had been assuming very high dose of cholecalciferol since 20 months (cumulative 78,000,000UI, mean daily 130,000UI), as indicated by a non-conventional protocol for multiple sclerosis." "This case confirms that vitamin D intoxication is possible albeit with a really high dose." This is a truly insane dosage but all this case says is that however created this protocol is dangerously incompetent.
Yeah, 130K IU / day is ~20x what's typically regarded as safe.