I think the future is very grim for biodiversity. Even if we stopped destroying habitats tomorrow, many larger animals are already living in small, isolated pockets surrounded by roads, farms, and industry. Meanwhile, plants and smaller animals face intense competition from invasive species - often brought in by accident thanks to the constant flow of goods around the globe. We're probably headed for a pretty homogen…
It's (past) time to start collecting genomes and marrow samples from as many critically endangered species as possible. Unextinction is a difficult problem, but without the necessary material, it's impossible.
Sure, that's going to favor charismatic megafauna. But we like those, it's right in the name. And it's no substitute for building wildlife corridors, managing park lands better, extirpating invasives, and all the rest. But it doesn't draw resources away from those things either.