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Low Doses of LSD Acutely Increase BDNF Blood Plasma Levels in Healthy Volunteers

pubs.acs.org

21–30 of 138 posts

Re: Low Doses of LSD Acutely Increase BDNF Blood Plasma Levels in Healthy Volunteers

#23

Earlier quoted context omitted.

Please, you're on a discussion site where the main demographic is actively microdosing to improve their productivity at startups inbetween two editions of Burning Man. You'd be hardpressed to find someone without a first-hand experience of acid. But yeah, you pretty much tend to remember everything that happens to you during a trip, even years afterwards, which naively makes me believe your brain and memories become…

I don't microdose and I can't see how it improves productivity over say ritalin or other methylphenidates.

Probably because you don't?

I don't drink beer, I can't see why it tastes better then Grog.

Re: Low Doses of LSD Acutely Increase BDNF Blood Plasma Levels in Healthy Volunteers

#26
post #2

Anyone with first hand experience of LSD ?

See https://www.erowid.org/chemicals/lsd/lsd.shtml , look for the 'experiences' links halfway down. Lots more on everything else, excellent impartial site, donate a little if you can.

I’m not sure why people are downvoting this. Erowid is a treasure trove of first hand experiences for a huge variety of illicit substances. It’s been around forever, and you can, if I recall, generally find good, pragmatic advice on how to approach a given drug.

Re: Low Doses of LSD Acutely Increase BDNF Blood Plasma Levels in Healthy Volunteers

#27
post #16
post #15

Earlier quoted context omitted.

Yes, I have tried it. Only micro-doses. It takes about an hour to kick in, and for me, lasts about 6-8 hours. It feels like it silences any inner critic in me, so I am a lot more free thinking. I have used it several times to overcome getting stuck on a programming problem, but I have to write the solution down because I usually get too distracted while using it to be able to focus enough to implement. The problems i…

Sounds like you had a bit more than a micro-dose, but interesting way of applying these doses!

Yep, i think you shouldn't get visuals from micro doses.

Re: Low Doses of LSD Acutely Increase BDNF Blood Plasma Levels in Healthy Volunteers

#28

Does this imply that high doses of LSD do not increase BDNF levels?

They didn’t research that question, and I don’t see any reason why it would be implied from their findings.

In the Abstract section it is shown that 20 micrograms does not increase BDNF levels after 2 hours, as opposed to 5 micrograms. It is shown however that it increases after 4 hours. That was a little confusing

Re: Low Doses of LSD Acutely Increase BDNF Blood Plasma Levels in Healthy Volunteers

#29

Earlier quoted context omitted.

See https://www.erowid.org/chemicals/lsd/lsd.shtml , look for the 'experiences' links halfway down. Lots more on everything else, excellent impartial site, donate a little if you can.

I’m not sure why people are downvoting this. Erowid is a treasure trove of first hand experiences for a huge variety of illicit substances. It’s been around forever, and you can, if I recall, generally find good, pragmatic advice on how to approach a given drug.

I've met this before. The vast majority of people on HN are pretty even-handed about things but there's just a few for whom anything that isn't anti-drug, if even just plain facts that don't show drugs in a bad light, will annoy them. Just how it is, don't worry about it.
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