The First Randomized Controlled Trial on Vitamin D and Covid-19
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The First Randomized Controlled Trial on Vitamin D and Covid-19
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Re: The First Randomized Controlled Trial on Vitamin D and Covid-19
#2Noteworthy that this is in combination with anti-viral drugs at hospital admission: hydroxychloroquine (400 mg every 12 hours on the first day, and 200 mg every 12 hours for the following 5 days), azithromycin (500 mg orally for 5 days). Regardless, I'm going to assume this means being outside and getting sun is good for me.
Re: The First Randomized Controlled Trial on Vitamin D and Covid-19
#3From the results:
“Of 50 patients treated with calcifediol, one required admission to the ICU (2%), while of 26 untreated patients, 13 required admission (50%) p value X2 Fischer test p Which sounds like as strong a signal as a study of this scale could hope to show.
Re: The First Randomized Controlled Trial on Vitamin D and Covid-19
#4"Don't go outside, you'll get COVID", sounds more and more like horrible advice. Before knowing the virus died in sunlight, I still couldn't fathom why people were avoiding going out to parks and stuff. It was totally non sequitor.
Re: The First Randomized Controlled Trial on Vitamin D and Covid-19
#5Noteworthy that this is in combination with anti-viral drugs at hospital admission: hydroxychloroquine (400 mg every 12 hours on the first day, and 200 mg every 12 hours for the following 5 days), azithromycin (500 mg orally for 5 days). Regardless, I'm going to assume this means being outside and getting sun is good for me.
Azithromycin is a common antibiotic, not an anti-viral drug. This is an important distinction. Also hydroxychloroquine is an anti-malarial drug, which is also not an anti-viral.
Re: The First Randomized Controlled Trial on Vitamin D and Covid-19
#6Noteworthy that this is in combination with anti-viral drugs at hospital admission: hydroxychloroquine (400 mg every 12 hours on the first day, and 200 mg every 12 hours for the following 5 days), azithromycin (500 mg orally for 5 days). Regardless, I'm going to assume this means being outside and getting sun is good for me.
All patients received hydroxychloroquine and azithromycin, i.e. the control group also, meaning the difference in outcome between the intervention and control groups is not due to these drugs.
Re: The First Randomized Controlled Trial on Vitamin D and Covid-19
#7"Don't go outside, you'll get COVID", sounds more and more like horrible advice. Before knowing the virus died in sunlight, I still couldn't fathom why people were avoiding going out to parks and stuff. It was totally non sequitor.
Because the parks have people in them not wearing masks?
Re: The First Randomized Controlled Trial on Vitamin D and Covid-19
#8"Don't go outside, you'll get COVID", sounds more and more like horrible advice. Before knowing the virus died in sunlight, I still couldn't fathom why people were avoiding going out to parks and stuff. It was totally non sequitor.
Because the parks have people in them not wearing masks?
You don't need masks if you are maintaining distance of 6 feet. Masks are for situations where distance can not be maintained such as trains and stores.
Re: The First Randomized Controlled Trial on Vitamin D and Covid-19
#9Noteworthy that this is in combination with anti-viral drugs at hospital admission: hydroxychloroquine (400 mg every 12 hours on the first day, and 200 mg every 12 hours for the following 5 days), azithromycin (500 mg orally for 5 days). Regardless, I'm going to assume this means being outside and getting sun is good for me.
To be clear, all patients received these supplemental drugs, as at the time they were considered the best standard of care. (Also to be clear: they're not anti-virals.)
Of the 75 patients in the trial, 50 people received additionally Vitamin D3 supplementation (in the form of calcifediol), and 25 did not.
Notably, though, diabetes and high blood pressure were substantially more frequent in the control group, which are HUGE risk factors. Also they didn't track BMI or obesity.
Still, check out table 2. Even with these limitations, seems powerful.
Re: The First Randomized Controlled Trial on Vitamin D and Covid-19
#10Noteworthy that this is in combination with anti-viral drugs at hospital admission: hydroxychloroquine (400 mg every 12 hours on the first day, and 200 mg every 12 hours for the following 5 days), azithromycin (500 mg orally for 5 days). Regardless, I'm going to assume this means being outside and getting sun is good for me.
Except for all the skin cancer, right?
FWIW, I was told that when the Sun is above 45 degrees over the horizon you will accrue DNA damage, and it stacks up over your entire lifetime. There is no "reset" or "heal", it just adds up.
For that reason I'm doing my darnest best to stay in the shade between 9am and 3pm. Or covering clothing.