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Supercomputer analysis of Covid-19 leads to new theory

elemental.medium.com

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Re: Supercomputer analysis of Covid-19 leads to new theory

#2
I can't really see why you would need a supercomputer to do the analysis they did (it shows SC centers are getting desperate for users; I wouldn't even have been allowed to run this code on a supercomputer when I was an academic, because it didn't need interconnect for strong scaling.

Re: Supercomputer analysis of Covid-19 leads to new theory

#5
The study itself:

https://elifesciences.org/articles/59177

Excerpts from the abstract:

    Bradykinin is a potent part of the vasopressor system that induces
    hypotension and vasodilation and is degraded by ACE and enhanced by 
    the angiotensin1-9 produced by ACE2.
...

    This very atypical pattern of the RAS is predicted to elevate 
    bradykinin levels in multiple tissues and systems that will likely 
    cause increases in vascular dilation, vascular permeability and 
    hypotension.
https://en.wikipedia.org/wiki/Bradykinin

Re: Supercomputer analysis of Covid-19 leads to new theory

#7
post #2

I can't really see why you would need a supercomputer to do the analysis they did (it shows SC centers are getting desperate for users; I wouldn't even have been allowed to run this code on a supercomputer when I was an academic, because it didn't need interconnect for strong scaling.

Maybe to test the algorithms and results, so that next time something like this happens there can be a list of suggested treatments ready far sooner.

Re: Supercomputer analysis of Covid-19 leads to new theory

#8
post #3

The anthropomorphization of computers (especially powerful ones) is pretty annoying. A _person used a supercomputer_ to analyze Covid-19, and I’m guessing the theory didn’t just ‘emerge’ from the computer.

"I'm sorry Dave. I'm afraid I can't do that."

Re: Supercomputer analysis of Covid-19 leads to new theory

#10
post #3

The anthropomorphization of computers (especially powerful ones) is pretty annoying. A _person used a supercomputer_ to analyze Covid-19, and I’m guessing the theory didn’t just ‘emerge’ from the computer.

Likewise while a computer can produce data quite well, theories are still a purely human domain.
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