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TIL: Oxytocin and OxyCotin are different drugs that are both pain killers. I remember being prescribed Oxytocin after my surgery and it was a fun woozy drug. Never tried OxyContin.
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If doctors only prescribed opioids it would be simple, but they deal in all sorts of constantly evolving drugs where new research may overturn previous assumptions. Trusting the research and heavily punishing those who falsify data seems a lot more sane.
I will counter this one with a hypothetical for you. Monsanto, or Bayer now I guess, trots out a totally safe guys we pinky-swear pesticide. Would you add a little to your drinking water every day? Safety sheets say it can't hurt. You would probably not do this because you have a historical association with pesticides turning out to be rather broader in impact than was originally let on. You understand that history.…
Does your understanding of the companies history outweigh your experience of the formats history?
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Yep, completely different system. Same attitude, though.
I really don't understand what you mean by 'culture' and 'attitude'; please explain.
Canadian healthcare is great, and dissimilar to American, in that it's treated as a public good.
Canadian healthcare is not great, and similar to American, in that a lot of prescription decisions are made from a similar cultural perspective as in the US, ie drugs are handed out like candy.
TIL: Oxytocin and OxyCotin are different drugs that are both pain killers. I remember being prescribed Oxytocin after my surgery and it was a fun woozy drug. Never tried OxyContin.
Oxytocin is a hormone, completely unrelated. The words you're thinking of are oxycodone and oxycontin, and they are not different drugs. Oxycontin is a time-release formulation of oxycodone.
Somewhat coincidentally for the purposes of this conversation, it also inhibits chemical dependence (including opioids, which includes oxycontin and oxycodone). [1][2]
[1] https://www.sciencedirect.com/science/article/pii/S009130571...
[2] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5089904/
This concludes the reply relevant section of my comment.
Sidenote (mostly me screaming into the void): due to excruciating constant chronic pain from a botched surgery, I took three oxycodone for 4 years (March 2015-August 2019) every single day. It enabled me to work and live a (greatly diminished) life. For all of the harm the crisis inflicted—and the Sacklers did great evil for great reward—there is really not another class of medication that would have kept me functioning.
Fortunately for me, I managed to get a very good job with great healthcare and I immediately used that to have a corrective surgery with the best surgery center in the country. This took me from about 65% functional (medicated) to about 85% functional, unmedicated. That last 15% is never coming back, and I have to live with the fact a doctor permanently damaged my body in an uncorrectable way.
But, over the course of my treatment, the backlash against opioids began to make it difficult for my pain management clinic to provide the treatment I needed even though I was completely compliant (and had the regular drug tests to prove it—so many cups of pee). I would be dead without opioids. I would have killed myself. There are many more like me who still suffer from unmanageable pain who either cannot get the medication they need. There are many people who are not here because of opioids as well so I completely understand the backlash, I just hope we don’t overcorrect.
The Sacklers harm cannot be undone, but their reward can be—expropriate it all (leave them an apartment with running water and a roof so that it’s technically legal).
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Oxytocin is a hormone, completely unrelated. The words you're thinking of are oxycodone and oxycontin, and they are not different drugs. Oxycontin is a time-release formulation of oxycodone.
Expanding on this, oxytocin has many known (and likely unknown) purposes but is most closely associated with context dependent social bonding and exclusion, sex, and childbirth. Somewhat coincidentally for the purposes of this conversation, it also inhibits chemical dependence (including opioids, which includes oxycontin and oxycodone). [1][2] [1] https://www.sciencedirect.com/science/article/pii/S009130571... [2] ht…
Curious: how much did your pain affect your sleep? Did you need the pills to sleep too?
What this family did was pure evil, they should all be in jail not negotiating a settlement that will leave them financially secure and amongst the richest Americans. Imagine if this scenario played out in China.
I imagine a couple ways this would play out in china 1. nobody ever hears nor finds out anything because it's all kept within the party. 2. they are publically shamed and they are sent to a re-education camp never to be seen or heard again. my 2 cents...
All-around-tech-bro-knowledge is strong in this thread. Doctors prescribe opiates all over the world, including oxycontin. Nowhere else is it a problem as big as in the US. Before wanting to withdraw prescription rights and sue MDs on a personal basis, perhaps people could think about the american exception? The US opiate problem is cultural and the responsibility is on both sides of the doctor-patient fence. The mor…
But the US and NZ are the only two countries that allow DTC drug marketing. And Purdue in particular was monstrous (in size and as an evil creature) in their direct to healthcare provider marketing.
I would argue this a MUCH larger contributing factor than any cultural differences, and actually causing some 'cultural' differences.
Where else is a drug pusher allowed to legally access a database of all scripts written by which doctors in order to target the top 1% of script writers who make up a large % of the profit. Then pay HUGE commissions to pushy non-educated salespeople - armed with criminally false 'research' funded by shell 'non-profits' - to bribe doctors to write even more.
Not to mention Purdue actively incentivizing pill mill Doctors, actively reaching out to obvious criminal MDs to get them to sell more drugs!!!!
It's disgusting and they need to be held accountable for manslaughter. all ill-gotten gains should be reposed and used for treatment.
If this were any other drug dealer their cash/cars/etc would be seized immediately and the accused would have to prove the money was not ill-gotten to get it back.
Put the Sackler's on the treasury sanctions list just like we do with Cartel leaders. Maybe them museums will start chiseling their names off of the buildings.
I never understand why doctors are not blamed for prescribing these. Are doctors not supposed to be responsible for prescriptions? If they are not, should we stop allowing them to prescribe? Why don’t doctors unions throw out members who would claim to have been hoodwinked by pharmaceutical companies?
It's because doctors and hospitals are increasingly evaluated based on patient satisfaction instead of patient outcomes. It's why you'll walk into a medical plaza lobby that looks like a 4-star hotel, with fountains and art on the wall, and why the doctor will write you a prescription for an absurd dose of narcotics after surgery. After you've been cut open, it's normal to be in some pain for a while, but if the doct…
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"doctors should have known the manufacturers' claims were bogus" is shifting the blame. The real blame should be focused on the manufacturers making false claims in the first place.
There's plenty of blame to go around, both can be at fault. My family doctor, for example, warned me to be very careful of the Oxytocin I was given by the hospital (without any warnings) after my wisdom teeth were removed.
Furthermore, opioids shouldn't even be used as first line after wisdom teeth removal - across Europe you'd be sent home and told to take paracetamol or ibuprofen, because those medications generally work very well for inflammation-type pain.