Earlier quoted context omitted.
Why would you want to replace Lua in this space? At least why replace with another dynamically typed, imperative scripting language, but without tail-call optimization? What would be the gain?
I was wondering the same as the parent, and in my case it's library support (e.g. NumPy) and compatibility/familiarity in the space (VFX) where Python is everywhere and Lua is unheard of.
The only other implementation that really supports it is PyPy which is not in any sense more lightweight.