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Brain-Gut Circuit Lets Microbiota Directly Affect the Sympathetic Nervous System

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Re: Brain-Gut Circuit Lets Microbiota Directly Affect the Sympathetic Nervous System

#51

Post by fodmap »

ElKrist wrote: post #49
fodmap wrote: post #45

Earlier quoted context omitted.

Thank you for your comment. Is your girlfriend sensitive to galacto-oligosaccharides (GOS)? I know there this enzyme therapy for that problem https://www.monashfodmap.com/blog/new-research-enzyme-therap... but I haven't try it. I'm sensitive to some GOS but I haven't being professionally tested for them. I did a fructose malabsorption test though, and I tested positive.

Yes she reckons the enzyme works both for FOS and GOS. Things like onions and garlic were an absolute no-go before she found the enzyme. Now she can eat them She has to take an enzyme pill before each meal that includes this group though. It's fairly harmless so she doesn't mind, it's just a bit of additional cost on our food. If you're motivated, you can follow a protocol ("food challenges") to know which group(s) y…

Yes I'm in the 'middle' so to speak of that Monash FODMAP diet challenge, and I'm finding some relief but I still need to do a lot of triage, and expand my food options because they're severely limited now.

I'll talk with my doctor to see if I should give that enzyme pill a try.

Thanks again!

Re: Brain-Gut Circuit Lets Microbiota Directly Affect the Sympathetic Nervous System

#52

Post by msandford »

karmakaze wrote: post #25
PragmaticPulp wrote: post #6

Earlier quoted context omitted.

Interesting. Every time I go low-carb, I loose my taste for sweets in about 3 weeks. Anything sugary starts to taste bad until I re-acclimate to it.

These are interesting comments. My normal diet of mostly starchy carbs leaves me without any cravings for sugary things even if they're just lying around near me. The moment I start eating sugary things I get hungry so fast, not just for sugary things but anything and it's hard to concentrate. I also have a weird condition where I'll forget to eat to the point of low blood sugar, sometimes drastically so--speech or v…

You might try the keto diet for a while and see how you like it. There are two ways in which it might help you.

1. Very low carb means your blood sugar never rises sharply, and then your body doesn't over-correct which can lead to that hypoglycemic feeling.

2. Adapting to utilize primarily fat means that blood sugar largely doesn't enter into the equation and urgent eating to raise blood sugar can go away. It usually takes people days to weeks to get adapted and feel back to normal.

Re: Brain-Gut Circuit Lets Microbiota Directly Affect the Sympathetic Nervous System

#53

Post by adrianN »

chrisco255 wrote: post #13
pfundstein wrote: post #9

Earlier quoted context omitted.

The key to a good diet is balance. Too much red meat has equally severe health implications, leading to a higher risk for heart disease, cancer, diabetes, and premature death.[1][2] [1] https://www.health.harvard.edu/staying-healthy/whats-the-bee... [2] https://pubmed.ncbi.nlm.nih.gov/26780279/

Mankind evolved to eat red meat. We developed fire for it. We invented spears and bow hunting for it. It's one of the healthiest foods you can consume, has been part of the human diet for over 2 million years... and besides the noted protein, it contains B12, Zinc, Selenium, Iron, Niacin, B6, Phosphorous and many other valuable nutrients. You can live exclusively off a diet of just red meat and live a long, healthy l…

Mankind didn't evolve to live much longer than seeing their grandchildren become independent, which used to happen in your fifties or early sixties.

Re: Brain-Gut Circuit Lets Microbiota Directly Affect the Sympathetic Nervous System

#54

Post by phonypc »

pfundstein wrote: post #28
phonypc wrote: post #27

Earlier quoted context omitted.

Life expectancy being 25 doesn't mean nobody lives past 25. Estimates that low for early humans is skewed by huge infant mortality rates. IIRC living into the 40s or 50s was typical for an early human that survived to adulthood. 60s or 70s not uncommon.

>IIRC living into the 40s or 50s was typical for an early human that survived to adulthood. >60s or 70s not uncommon. I would love to see the evidence you're referencing. > Life expectancy being 25 doesn't mean nobody lives past 25. You're absolutely right.

I'm half-remembering things from an article I probably read years ago. Upon a quick search, this looks like a decent source maybe?

http://www.unm.edu/~hkaplan/KaplanHillLancasterHurtado_2000_...

As another poster pointed out, we can't really know how long people lived in prehistory. The numbers come from contemporary hunter-gatherers.

Re: Brain-Gut Circuit Lets Microbiota Directly Affect the Sympathetic Nervous System

#55

Post by graeme »

fodmap wrote: post #42
Vaslo wrote: post #15

The brain gut connection is incredible. For years I suffered with terrible IBS where I would almost always get nauseous after eating and would often need to immediately go to the bathroom. I also had a very difficult time gaining weight. I tried all kinds of drugs - prescriptions to treat nausea, malabsorption, even gastroparesis (slow emptying of the stomach). Nothing worked and a few of the prescriptions were nerve…

Are you completely free from IBS (that would be a dream come true for me) or are you still suffering recurrent bursts? I'm still fighting my way out of it. The Low FODMAP diet is helping me, and I have an eye on hypnotherapy as my next step. See https://lens.monash.edu/@medicine-health/2019/06/24/1351605/...

I tried hypnotherapy with the nerva app, made by a monash researcher. Was posted here a while ago.

I’m only about a week in, big improvement in symptoms. I had tried low fodmap before, it helped but didn’t cure.

The idea seems to be that fodmaps aren’t causing an abnormal reaction, but the gut nerves are overactive.

Re: Brain-Gut Circuit Lets Microbiota Directly Affect the Sympathetic Nervous System

#56

Post by fodmap »

graeme wrote: post #55
fodmap wrote: post #42

Earlier quoted context omitted.

Are you completely free from IBS (that would be a dream come true for me) or are you still suffering recurrent bursts? I'm still fighting my way out of it. The Low FODMAP diet is helping me, and I have an eye on hypnotherapy as my next step. See https://lens.monash.edu/@medicine-health/2019/06/24/1351605/...

I tried hypnotherapy with the nerva app, made by a monash researcher. Was posted here a while ago. I’m only about a week in, big improvement in symptoms. I had tried low fodmap before, it helped but didn’t cure. The idea seems to be that fodmaps aren’t causing an abnormal reaction, but the gut nerves are overactive.

Do you mean this https://www.mindsethealth.com/nerva?

I'll take a look. Thank you!

Re: Brain-Gut Circuit Lets Microbiota Directly Affect the Sympathetic Nervous System

#57

Post by ianai »

starfallg wrote: post #37
nikkwong wrote: post #21

Earlier quoted context omitted.

Would you mind disclosing who the doctor was? I have been dealing with this for years and it's been wreaking havoc on my personal and professional lives. Doctors in my area are not familiar with my condition and don't have a solution. I'm especially tired of the malabsorption, dietary restrictions, sleeping issues, inability to gain weight, edema.. a whole laundry list. Would love to hear your doctor's opinion. I am…

I had similar experiences, but with amitriptyline at the lowest dose of 10mg taken every night. At 25mg I was too drowsy. It drastically improved all of my chronic problems almost immediately - gut problems (IBS-D), inability to sleep more than a few hours, and issues with peripheral nerves. Amitriptyline has a slight sedative effect compared to nortriptyline, which is good if you suffer problems with sleep, but has…

Ami. also helps with migraines. Foods can also be migraine triggers and should be carefully observed when trying to tackle them. There’s a lot going on there between gut and brain.

Re: Brain-Gut Circuit Lets Microbiota Directly Affect the Sympathetic Nervous System

#58

Post by ianai »

james_s_tayler wrote: post #41
agumonkey wrote: post #39

Earlier quoted context omitted.

I don't know how doctors would feel but maybe it's time to have a system to query more than one doctor for patient's ailments. Instead of waiting to run into the occasional pro that actually knows your issue and fix it with a switch. No need for moonshot AI just an large aggregative system that let's curious doctor that are very capable in a subfield scan open issues for diagnosis.

That put that in a pitch deck and go get some funding.

Might run into severe ego issues blocking doctors from using such service, but probably not enough to make it infeasible.

Re: Brain-Gut Circuit Lets Microbiota Directly Affect the Sympathetic Nervous System

#59

Post by graeme »

fodmap wrote: post #56
graeme wrote: post #55

Earlier quoted context omitted.

I tried hypnotherapy with the nerva app, made by a monash researcher. Was posted here a while ago. I’m only about a week in, big improvement in symptoms. I had tried low fodmap before, it helped but didn’t cure. The idea seems to be that fodmaps aren’t causing an abnormal reaction, but the gut nerves are overactive.

Do you mean this https://www.mindsethealth.com/nerva ? I'll take a look. Thank you!

Yup!

Re: Brain-Gut Circuit Lets Microbiota Directly Affect the Sympathetic Nervous System

#60

Post by doublerebel »

agumonkey wrote: post #39
Vaslo wrote: post #15

The brain gut connection is incredible. For years I suffered with terrible IBS where I would almost always get nauseous after eating and would often need to immediately go to the bathroom. I also had a very difficult time gaining weight. I tried all kinds of drugs - prescriptions to treat nausea, malabsorption, even gastroparesis (slow emptying of the stomach). Nothing worked and a few of the prescriptions were nerve…

I don't know how doctors would feel but maybe it's time to have a system to query more than one doctor for patient's ailments. Instead of waiting to run into the occasional pro that actually knows your issue and fix it with a switch. No need for moonshot AI just an large aggregative system that let's curious doctor that are very capable in a subfield scan open issues for diagnosis.

The Human Diagnosis Project (YC S12) is something like this. You can see a sample of the cases on their Twitter:

https://twitter.com/hdx

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