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Glucosamine Supplementation Reduces All-Cause Mortality: Study

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Re: Glucosamine Supplementation Reduces All-Cause Mortality: Study

#61

https://examine.com/supplements/glucosamine/ Always used this site when trying to find unbiased information, and also not be to hyped about a single study. However now the effect matrix is hidden behind a paywall. When talking about joint health: As a young and very active person my biggest problem is overtraining injuries. Wish I knew how to be able to train as much as I would like to, with just a simple supplement…

There's always peptides that do work with mouse models but there aren't any decent safety studies on them with humans. I really wish there was a push to get safety and efficacy studies around BPC-157 and other peptides.

Re: Glucosamine Supplementation Reduces All-Cause Mortality: Study

#64

Earlier quoted context omitted.

there's no reason to believe macromolecules like glucosamine benefit the body any more than regular, nutritious food. ingested nutrition generally gets broken down into amino acids and the like in the digestive system before it gets distributed to the rest of the body to be reconsistuted into cells and tissue. cartilage in particular is scaffolding and generally must be constructed by other cells from very basic mole…

As someone that has taken various vitamins and supplements over the years, glucosamine is the one where I truly feel a difference. In my knees, my back stopped cracking when I woke up, and generally just better. Others I take based on blood tests if something is out of whack for a time.

For me too.. And I'm usually extremely sceptical of food supplements and general quackery.

My joints have also been really cracky since I was a child. This seems a bit less but still present with the glucosamine.

But my elbow joints are often sore due to being on the computer way too much and every time I start taking it again it fades in a day or two. I don't think I'm imagining it :) Many other stuff I don't feel much benefit to.

Re: Glucosamine Supplementation Reduces All-Cause Mortality: Study

#65
post #52

Earlier quoted context omitted.

How are you getting rapamycin? I'm interested in it's benefits for autoimmune diseases but it seems quite expensive (in the US).

Some doctors will prescribe it for off-label use, but this is pretty rare. It's possible to purchase it from overseas websites as it is not scheduled, but this is technically not legal, and it will still cost quite a bit out-of-pocket. With that said, it can definitely be potentially dangerous, and dosing+frequency would have to carefully be paid attention to, as well as monitoring results via blood tests imo, and ha…

Any other advice for folks? What do you think of NR?

Re: Glucosamine Supplementation Reduces All-Cause Mortality: Study

#66
post #33

To people who put too much stock in these "studies", consider this: as of July 2020 we _still_ have no conclusive answer if _eggs_ are good for you or not. What makes you believe this is any different?

Why would eggs, for which there isn't a chemical formula, nor a standard preparation, be easier to study? What even does "good for you" mean?

Don't get confused between mass-media popular "science" and things science can actually do - like measure whether a dozen eggs a day will raise your LDL and HDL (cholesterol) and cause heart disease - and drawing wild conclusions (especially right now) from pre-print articles that are used to sell magazine articles to use as justification to eat chocolate and drink wine under the guise of "it's good for you".

Re: Glucosamine Supplementation Reduces All-Cause Mortality: Study

#67
post #18

Earlier quoted context omitted.

Yes - cartilage. If you eat chicken or something like that, eat the cartilage. You can do this on pre-cooked chickens you get from Sam's Club / Costco. If you eat chicken breasts only (which a lot of health-conscious people do), you don't get this benefit. I talked to Dr.Yang Jwing Ming (one of the few Kung Fu practioners with a Western phd and he said eating cartilage is one of the best ways to help reduce the risk…

Westerners have eaten pig ears for centuries.

Also explains how 'Westerners' have been living so long for centuries, especially before the 1960s.

Re: Glucosamine Supplementation Reduces All-Cause Mortality: Study

#68
post #18

Earlier quoted context omitted.

Westerners have eaten pig ears for centuries.

I would be surprised if I've met anyone in the US who has eaten pig ear nor the chicken feet you see next to them in the hispanic market. And just about everyone would react to the ick factor. I don't think it's as common as you think: https://en.wikipedia.org/wiki/Pig%27s_ear_(food) .

It's not super-common but it's nothing out of the ordinary either. Many restaurants in Southern Europe, including France, serve dishes such as pig feet, pig snout or pig head.

Re: Glucosamine Supplementation Reduces All-Cause Mortality: Study

#69

Earlier quoted context omitted.

there's no reason to believe macromolecules like glucosamine benefit the body any more than regular, nutritious food. ingested nutrition generally gets broken down into amino acids and the like in the digestive system before it gets distributed to the rest of the body to be reconsistuted into cells and tissue. cartilage in particular is scaffolding and generally must be constructed by other cells from very basic mole…

As someone that has taken various vitamins and supplements over the years, glucosamine is the one where I truly feel a difference. In my knees, my back stopped cracking when I woke up, and generally just better. Others I take based on blood tests if something is out of whack for a time.

What brand and dosage do you take?

Re: Glucosamine Supplementation Reduces All-Cause Mortality: Study

#70

Earlier quoted context omitted.

Would chicken bone broth have it?

No, it's a myth: https://www.npr.org/sections/thesalt/2015/02/10/384948585/ta... https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533136/ https://www.motherjones.com/environment/2015/11/truth-about-...

None of those mention Glucosamine. And they seem to be sour grapes articles, not sure why. One of the “myths” they dispel is “bone broth tastes good”.

It does raise some good thoughts on why it’s not a super food.

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