51–60 of 153 posts
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As someone that has taken various vitamins and supplements over the years, glucosamine is the one where I truly feel a difference. In my knees, my back stopped cracking when I woke up, and generally just better. Others I take based on blood tests if something is out of whack for a time.
Can I ask your age (or which decade if you prefer!)?
I've been supplementing glucosamine along with a large amount of other things for awhile now. I'm not too bullish on it in humans, but it doesn't seem like it hurts, and is definitely cheap: https://nearcyan.com/supplements My latest favorites that I'm a bit more hopeful for are glycine, spermadine, and rapamycin.
How are you getting rapamycin? I'm interested in it's benefits for autoimmune diseases but it seems quite expensive (in the US).
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Yes - cartilage. If you eat chicken or something like that, eat the cartilage. You can do this on pre-cooked chickens you get from Sam's Club / Costco. If you eat chicken breasts only (which a lot of health-conscious people do), you don't get this benefit. I talked to Dr.Yang Jwing Ming (one of the few Kung Fu practioners with a Western phd and he said eating cartilage is one of the best ways to help reduce the risk…
Would chicken bone broth have it?
Also here is his video on Sulforaphane which Glucosamine activates. He goes into detail as to how this mechanism works. Because of his video/latest research presented I changed to taking Broccomax because you need Myrosinase to actvite the SGS for it's full effect, he goes into detail on this here: https://www.youtube.com/watch?v=qAb1eQbRAe0
Cochrane Review he uses as his primary source: https://www.cochrane.org/CD007176/LIVER_antioxidant-suppleme...
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Yes - cartilage. If you eat chicken or something like that, eat the cartilage. You can do this on pre-cooked chickens you get from Sam's Club / Costco. If you eat chicken breasts only (which a lot of health-conscious people do), you don't get this benefit. I talked to Dr.Yang Jwing Ming (one of the few Kung Fu practioners with a Western phd and he said eating cartilage is one of the best ways to help reduce the risk…
I really hope at some point in our lifetimes, the deleterious effects of animal protein are pervasively understood by educated Americans to the point where consuming animal parts for their anti-inflammatory benefits would be an oxymoron on par with smoking to prevent cancer. An overwhelming body of scientific evidence suggests that humans are omnivores and not carnivores and the human body evolved to process animal p…
I've given glucosamine to my dogs for years, and I can clearly notice a difference in their joint health and how stiff and sore they are after long runs ('long-run': 15-25 miles, measured on GPS collars). When I run out of glucosamine, or just drop off of giving it to them for whatever reason, I see them fall back pretty quickly. And when I restart them on it, I notice a response in a few days. I also give give them…
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Westerners have eaten pig ears for centuries.
I would be surprised if I've met anyone in the US who has eaten pig ear nor the chicken feet you see next to them in the hispanic market. And just about everyone would react to the ick factor. I don't think it's as common as you think: https://en.wikipedia.org/wiki/Pig%27s_ear_(food) .
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Individually. Sometimes a few things are combined when a good option is available, but generally multivitamins don't give me what I want in the doses that I want. Since I tested all of my blood metrics beforehand, it's unlikely the market would have a 'perfect' vitamin for me. Especially since most of what I like to take isn't technically a vitamin. My diet is currently pretty un-optimized, so although I would prefer…
Id be curious what it would look like if you tested your blood now, stopped taking them all, and radically modified your died, what kind of results you would get in a couple weeks. Daily intake of, tomato juice, kefir, sardines, salmon, spinach, sunflower seeds, pumpkin seeds, pistachio, eggs. You could probably get a whole days worth of food into a snack, a salad, and a soup.
I do know there are a few people in the area that log literally every substance they eat in terms of grams, and then correlate it with all of their blood metrics, and use that to try to optimize each blood metric for what correlates with the lowest mortality rate. It's interesting, but this stuff is unfortunately a lot of work for average people to attempt. Here's a great example: https://twitter.com/Nearcyan/status/1282042301980835842
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there's no reason to believe macromolecules like glucosamine benefit the body any more than regular, nutritious food. ingested nutrition generally gets broken down into amino acids and the like in the digestive system before it gets distributed to the rest of the body to be reconsistuted into cells and tissue. cartilage in particular is scaffolding and generally must be constructed by other cells from very basic mole…
You raise a good point, but wouldnt taking glucosamine and chondroitin load you up (hopefully) on the base components required to then again make glucosamine and chondroitin locally in one's body?
“In the first study, glucosamine sulfate was given to healthy volunteers in doses of 750, 1500, or 3000 mg once daily. In the second study, oral glucosamine sulfate capsules (1500 mg) were given daily for two weeks to 12 people with osteoarthritis. Glucosamine concentrations in plasma and synovial fluid increased significantly from baseline levels […] but the levels are still ten- to a hundredfold lower than required to positively affect the cartilage (chondrocytes) to build new tissue”
⇒ the good news is that these molecules make it through the intestines intact, and arrive at the place where they are supposed to help. The bad news seems to be you would need to take huge doses.