In retrospect I think the collider would have been a better investment than the ISS because it would have yielded science that has game changing potential for us as a species and more science that we can use. I'd rather understand what we're made of than know how flora and fauna behave in orbital space.
What kind of game changing things are you thinking of? Colliders help us learn what model is correct (or rather let us eliminate incorrect models) of very low level physics. We don't remotely have any technology to do anything with physics at that low a level, so isn't knowing which model may be correct pretty much going to remain of theoretical and philosophical interest only? It's good to figure that out, but it is…
I'm an astronomer and I think the LHC is a better bet than the ISS. The ISS does no astronomy work and just diverts funds from science 9especially by demanding the shuttle stays) the microgravity / materials science is compromised by having people on board which means a high level of vibration from people and life support .
The 'science' it does do is mostly school science project stuff