The discovery and research of CRISPR makes in vivo genetic modification possible and safe, is going to absolutely revolutionize humanity. Imagine a world completely devoid of genetic diseases or with treatment for those diseases. Imagine a reduction in occurrence of over 50% of cancers. Imagine being able to change fundamental aspects of yourself. Imagine a grad student learning tools that can be used to recreate sma…
If you're looking for what is going to be the next digital/industrial/etc revolution, CRISPR is that thing .
Ask HN: What’s a big trend we should all be following?
271–280 of 313 posts
Re: Ask HN: What’s a big trend we should all be following?
#272Remote work. 20 years of progress were consolidated into the last 3 months. Previously, you saw people living in hubs like SF and NYC for the high salary and high prestige jobs. But when those jobs are available from anywhere, all of a sudden the "lifestyle cities" like Boulder, Boise, Chattanooga, etc. start to look a whole lot better. You no longer have to sacrifice the high-prestige career to live in a lower cost-…
I am really skeptical of this idea that suddenly people will be moving to small cities. For one, this assumes that people just move to big cities to work. Is there any research to prove that ? For most people, especially when they are younger, people gravitate to big cities for all the amenities that come with the big city living, jobs being one of them. So in essence, it is jobs chasing people into big cities, rathe…
Re: Ask HN: What’s a big trend we should all be following?
#273Space manufacturing. SpaceX Starship should get a kilogram to orbit for $250 (actually Elon's goal is to get the costs down to $10 per kilogram[1] which seems insanely crazy but be forewarned). Historic costs[2]: - Space Shuttle: $41,000/kg (24.4 t, ~$1B) - Delta IV Heavy: $14,600/kg (24 t, $350M) - Falcon Heavy 2R: $1,700/kg (57 t, $95M) A good first product to make in zero G is ZBLAN, fiber optics so clear that the…
Which brings us to what I think is a bigger issue: Space is a finite quantity, similar to land and EM spectrum. It's a land race for space. SpaceX and similar are racing to put their junk up their in orbit as soon as possible so they can squat. So who is going to regulate space? Will China Russia and North Korea respect ownership at 10KM up? What happens when GPS and GLONAS go out because of debris and some stupid wa…
The gist: we could trap ourselves on earth for generations with space debris.
Re: Ask HN: What’s a big trend we should all be following?
#274Earlier quoted context omitted.
Why is that useful? Who is clamouring to rebuild all the existing roads - which bikes already work on? Who is hoping to ride miles and miles in underground tunnels and pay to build them? Underground tunnels for fast no-traffic movement of people already exist as subways, and move orders of magnitude more people, many times faster.
Existing roads will slowly become populated with light electrics and covered (perhaps seasonally) with no need to deal with exhaust gases. Some businesses will begin to provide indoor parking for the electrics. Some parking garages will be turned over to electrics exclusively. There will be almost no new roads or tunnels. It will be a very inexpensive, organic and practical transition.
There's tiny advantage to not being rained on, but you will already want outdoors clothing for wind chill unless your entire route end to end is covered and heated, and if you're on an electric bike or scooter doing 20+mph you'll want some kind of protective wear as well, most likely.
Re: Ask HN: What’s a big trend we should all be following?
#275Giving up our freedoms and way of life for a virus that kills .26% of the people it infects (and 0.05% for ages 0-49.) https://www.cdc.gov/coronavirus/2019-ncov/hcp/planning-scena...
Re: Ask HN: What’s a big trend we should all be following?
#276Re: Ask HN: What’s a big trend we should all be following?
#277I think that the current world situation is going to be a large boost for VR (Virtual Reality). Before the pandemic I was much more in favour of AR (Augmented Reality) as a form of entertainment. VR requires so much more precision to get right and also (generally) prevents you from moving around too much in meat space. AR allows you to walk around an interact with things, which seems to be a much easier lift. However…
Re: Ask HN: What’s a big trend we should all be following?
#278Earlier quoted context omitted.
“Cancel culture” is making it worse for everyone. Say or do the wrong thing on social media at any point in time in history and you can lose everything. Social media has become a groupthink bent toward disorder. I just pick up on a lot more hostility than I remember from even 10 years ago. All the polls showing people expecting to wind up worse off than their parents and the consistent results for older generations v…
Maybe you shouldn't get to say everything out loud without backlash? Maybe being more considerate to others is something we should all strive for? I was like you, I hated this culture. I felt like someone was taking my liberties away. Then I decided to actually talk to be people with less privilege and I noticed that me talking shit on the internet isn't something that's necessary for me. I'd rather have everyone be…
Re: Ask HN: What’s a big trend we should all be following?
#279Earlier quoted context omitted.
Like I said "all have their own definition". If you are fine with using animal products if they did not suffer because of humans, you still can't use fossil fuel because obviously your goal then is to avoid animal suffering and billions of animals suffered and died as a direct consequence of humans using fossil fuel. Veganism can be turned and twisted however one wants its either based on total flawed concept or the…
I didn't say "humans should never cause animals to suffer." I said that humans shouldn't oppress animals, meaning that we shouldn't treat them as commodities and we should respect their rights. Obviously it's impossible to never cause any animal suffer, just as it's impossible to never cause any human to suffer. For instance, if you don't donate all of your available organs, you're causing another human to suffer and…
That however is not even veganism anymore.
>However, if you were maximizing utility, you still wouldn't eat meat or dairy products, because those things cause massive suffering to animals...
Humans have been doing animal population control since hundreds of years because we eat them. If we would not eat them we would need to find a non-lethal way to do that (which would probably still not respect their assumed rights), else many animals would have massive suffering too.
Nature never optimizes to reduce suffering it optimizes for survival. That's why a prey population can grows drastically faster than "healthy" and then gets reduced either by a predator population or the lack of resources. These circles repeat forever and humans have been "counter hunting" since hundreds of years for food and other animal products but also because we do not want exploding populations followed by mass extinction (sometimes called plagues). So if you really would want to maximizing utility and minimize suffering you would almost certainly have to go some middle way that does justify killing animals if it reduces more death and at that point it would be unethical to let the killed animal go to waist. That however doesn't work if animals should have the same rights as humans. And it also doesn't work with any popular interpretation of veganism.