Hacker News Board Hacker News, browsed like a classic message board
Live data from Hacker News

Covid-19: The T Cell Story

berthub.eu

Post reply on HN
Print view View original

21–30 of 149 posts

Re: Covid-19: The T Cell Story

#21

Post by thewarrior »

nodamage wrote: post #9

> And wherever we look, infections level off before 10%-20% of the population is infected. This is somewhat mysterious. This is not really true. Bergamo had a 58% infection rate as of last month: https://bergamo.corriere.it/notizie/cronaca/20_maggio_22/ber... Several prisons have seen infection rates in the 70-80% range: https://www.npr.org/sections/coronavirus-live-updates/2020/0... The USS Theodore Roosevelt had an…

I think you’re being too negative here. I’m not an expert.

My understanding is given that there is a pre existing T cell response that doesn’t mean that you will not be infected or that you will not have antibodies if infected. However it could totally be possible that when infected you are much less likely to show symptoms,die or spread it to others.

It’s a tough hypothesis to completely verify but the dip in deaths and infections in many places in spite of lifting lockdowns lends some support to this theory.

This controversial thesis has support from some experts like Dr Sunetra Gupta who teaches epidemiology at Oxford.

Re: Covid-19: The T Cell Story

#22

Post by Animats »

Animats wrote: post #7

The author asks some questions which can be answered by gathering some data. This suggests going back and re-testing for antibodies some populations from tightly packed groups - the cruise ship passengers, warship crew, and nursing home residents. The antibody tests are more accurate than they were two months ago. The key here is to find out how many people, definitely exposed to the virus, not only did not show any…

It looks like that's already been done, and there are tightly packed groups where the infection rate was 70-100%, as mentioned above. So, no existing immunity at all, probably. That was the claim in the original article, but the data does not bear it out.

Re: Covid-19: The T Cell Story

#23

Post by leptoniscool »

somewhereoutth wrote: post #16
nodamage wrote: post #9

> And wherever we look, infections level off before 10%-20% of the population is infected. This is somewhat mysterious. This is not really true. Bergamo had a 58% infection rate as of last month: https://bergamo.corriere.it/notizie/cronaca/20_maggio_22/ber... Several prisons have seen infection rates in the 70-80% range: https://www.npr.org/sections/coronavirus-live-updates/2020/0... The USS Theodore Roosevelt had an…

Curiously enough, after running some simulations in a supposed realistically connected population model (but much smaller n), I found linear growth occurring soon after the exponential phase. I suspect this might be a topological condition (i.e. the due to the distribution of connections) that limits the growth, in the same way a rope will burn linearly if you set fire to one end of it. Of course, a society is more c…

Are you able to share the code for this model?

Re: Covid-19: The T Cell Story

#24

Post by gonational »

lymeeducator wrote: post #11

T cell responses are interesting. Infectolab ( https://www.infectolab-americas.com/ ) and its originator Armin (Germany) are using T cell responses for tick borne diseases like: Borellia (Lyme), Bartonella and Babesia because antibody testing is difficult for these (broken via CDC specs as most labs won't test key proteins 31, 34 and never indicate which antibodies are present). Bartonella is very hard to test for wi…

Do you have any thoughts on the usage of consumption of Borax to treat Lyme disease (asking because your username)?

Re: Covid-19: The T Cell Story

#25

Post by erentz »

lymeeducator wrote: post #11

T cell responses are interesting. Infectolab ( https://www.infectolab-americas.com/ ) and its originator Armin (Germany) are using T cell responses for tick borne diseases like: Borellia (Lyme), Bartonella and Babesia because antibody testing is difficult for these (broken via CDC specs as most labs won't test key proteins 31, 34 and never indicate which antibodies are present). Bartonella is very hard to test for wi…

Note that Armin Labs are considered quacks by many. For one example [1]. I will leave it to others to do your own research but just wanted to recommend caution about their use. Especially for diagnosis of Lyme, plenty of tragic stories of people getting an Armin positive test while negative on the others and then being encouraged through years of serious antibiotic treatments only to have always been negative all along.

[1] https://forums.phoenixrising.me/threads/documentary-undercov...

Re: Covid-19: The T Cell Story

#26

Post by rpiguy »

hn_check wrote: post #19
codecamper wrote: post #6

What's the qualifications of the author before I go and invest time to read his/her theories?

It's Musk Syndrome -- be successful at something, to whatever degree, so think that a bit of Googling makes you an expert at everything, and that the world needs to hear your take . It's absolutely exhausting, and is easily the weakest element of sites like Hacker News. There is a certain sort of hubris in this industry that just foments this exaggerated sense of relevance to every topic.

Nearly as tedious as listening to experts in lab coats make wild projections that were wildly off and basing policy on it.

I’m very happy that we get lots of opinions from non-experts.

Re: Covid-19: The T Cell Story

#27

Post by nodamage »

thewarrior wrote: post #21
nodamage wrote: post #9

> And wherever we look, infections level off before 10%-20% of the population is infected. This is somewhat mysterious. This is not really true. Bergamo had a 58% infection rate as of last month: https://bergamo.corriere.it/notizie/cronaca/20_maggio_22/ber... Several prisons have seen infection rates in the 70-80% range: https://www.npr.org/sections/coronavirus-live-updates/2020/0... The USS Theodore Roosevelt had an…

I think you’re being too negative here. I’m not an expert. My understanding is given that there is a pre existing T cell response that doesn’t mean that you will not be infected or that you will not have antibodies if infected. However it could totally be possible that when infected you are much less likely to show symptoms,die or spread it to others. It’s a tough hypothesis to completely verify but the dip in deaths…

I'm not sure what exactly you think is negative? The claim that infections top out at 10-20% is clearly not true. Even if it were true, we don't really know enough yet to conclude that T-cells would be the reason why.

> It’s a tough hypothesis to completely verify but the dip in deaths and infections in many places in spite of lifting lockdowns lends some support to this theory.

This sounds like a pretty weak correlation to be honest. Just because a lockdown is officially lifted doesn't mean everyone suddenly reverts to their old behaviors.

Re: Covid-19: The T Cell Story

#28

Post by tacitusarc »

This article talks about cell mediated immunity whereby compromised cells are detected via peptides produced, but there's actually another mechanism that's still in the early stages of being understood called merocytophagy where an immune cell can partially "eat" another cell to see if it "tastes" sick.

Re: Covid-19: The T Cell Story

#29

Post by doliveira »

rpiguy wrote: post #26
hn_check wrote: post #19

Earlier quoted context omitted.

It's Musk Syndrome -- be successful at something, to whatever degree, so think that a bit of Googling makes you an expert at everything, and that the world needs to hear your take . It's absolutely exhausting, and is easily the weakest element of sites like Hacker News. There is a certain sort of hubris in this industry that just foments this exaggerated sense of relevance to every topic.

Nearly as tedious as listening to experts in lab coats make wild projections that were wildly off and basing policy on it. I’m very happy that we get lots of opinions from non-experts.

Yeah, experts won't get everything right so let's listen to the ignorants...

Pretty sure there is a phallacy that describes this line of thought. Multiple ones, probably.

Re: Covid-19: The T Cell Story

#30

Post by lymeeducator »

gonational wrote: post #24
lymeeducator wrote: post #11

T cell responses are interesting. Infectolab ( https://www.infectolab-americas.com/ ) and its originator Armin (Germany) are using T cell responses for tick borne diseases like: Borellia (Lyme), Bartonella and Babesia because antibody testing is difficult for these (broken via CDC specs as most labs won't test key proteins 31, 34 and never indicate which antibodies are present). Bartonella is very hard to test for wi…

Do you have any thoughts on the usage of consumption of Borax to treat Lyme disease (asking because your username)?

Never used it and wouldn't use it. I do not condone long term antibiotics either.
Post reply on HN