61–70 of 108 posts
Post-hoc "evolutionary just-so story" of the day: animals evolved under conditions of predation, where they'd tend to lose blood regularly, either in the process of fighting off/getting away from predators, or in the process of attacking prey with violent defenses. A species that goes years without losing any blood, is effectively operating its body in an evolutionary out-of-spec configuration. It might work , for a…
Implications for recruiting plasma donors?
Earlier quoted context omitted.
"half of the blood plasma " Important difference. Interesting point by aomix about the temperature, but that could be compensated for if it was needed. I haven't donated plasma in a long time, but pretty much the only thing I felt when the blood cells and platelets were returned was a light tickling near the needle and sometimes a faint chemical taste or smell, presumably from some component in the replacement fluid.…
> That ought to jolt the homeostatic controllers good, and that could well be one of the reasons for the beneficial effects Indeed, I'm wondering if this is yet another example of eustress. Other examples of eustress are exercise, sauna, and cryotherapy.
Implications for recruiting plasma donors?
Post-hoc "evolutionary just-so story" of the day: animals evolved under conditions of predation, where they'd tend to lose blood regularly, either in the process of fighting off/getting away from predators, or in the process of attacking prey with violent defenses. A species that goes years without losing any blood, is effectively operating its body in an evolutionary out-of-spec configuration. It might work , for a…
This may go part of the way to explaining why women have a longer life span then men, they're constantly having to manufacture new blood. Men only have to create new blood if they donate or suffer some injury, but women's bodies are generating new blood all the time.
There's some research (which I won't dig up at the moment; google "iron longevity" for a start) indicating that it's actually iron/heme which is bad. Women can get rid of it, at least while their fertility lasts. Men can't.
(And, in fact, donating blood regularly or even more often than usually recommended is the standard treatment for hemochromatosis, an inherited condition where too much iron is retained.)
This may go part of the way to explaining why women have a longer life span then men, they're constantly having to manufacture new blood. Men only have to create new blood if they donate or suffer some injury, but women's bodies are generating new blood all the time.
There's some research (which I won't dig up at the moment; google "iron longevity" for a start) indicating that it's actually iron/heme which is bad. Women can get rid of it, at least while their fertility lasts. Men can't.
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[0]: https://www.smithsonianmag.com/smart-news/females-live-longe....
The implication is not that young blood has specific positive properties, but that old blood has specific negative properties. Simply removing some of the "bad old blood" is already enough to measurably improve biomarkers. Identifying the bad stuff may go a long way to counteracting it in a more targeted way.
I don't know if Google's search results are accurate but I watched The African Queen recently and when Bogart gets leeches I googled if they are harmful and the first results said "No"
Earlier quoted context omitted.
> do not go somewhere and get your blood replaced with saline I just did that this morning when I donated blood. They said they needed the plasma badly, so they took the red blood cells and the plasma, and returned a saline solution. So maybe you just need to donate blood/plasma often to stay young?
study shows that people, who donate a lot of blood, suffer no serious ill effects and may even live longer than less frequent donors. https://sciencenordic.com/body-death-denmark/frequent-blood-...