Has there ever been an attempt to develop a vaccine against SARS or MERS? If so, what happened? Did it fail or was is just not needed anymore?
Covid-19 Vaccine Candidates
21–30 of 65 posts
Re: Covid-19 Vaccine Candidates
#22Earlier quoted context omitted.
If it did disappear, sure. But it won't. Way too many infected all over the globe now, eradication is impossible without a vaccine. Either it will eventually infect the entire world, or we'll vaccinate against it. Those are the only two options at this point. Even if an entire nation managed to eradicate it via distancing, it would only take a single carrier arriving by any means from another country to initiate a se…
Third option: we fight it with drugs and we prevent / reduce hospitalizations, and it becomes a disease like every other.
If a useful treatment shows up, that would certainly be an option, though vaccination would be preferable if feasible.
Re: Covid-19 Vaccine Candidates
#23Earlier quoted context omitted.
No, that's the first option - it will eventually infect the whole world no matter how much you improve outcomes or slow it down. Unmitigated R0 of SARS-CoV-2 is extremely high, we can't keep it contained with spreaders all over the globe creating micro clusters every day. I didn't say it'll kill the whole world, just infect. Many countries have already brought their case rates down to almost 0, and every single one t…
I have no hard data (and I don't think anyone has, at this point), but eradication is IMO going to be tricky even if we have a very potent vaccine, at least looking at how much it took for chicken pox.
Oh absolutely. Eradicating this thing via vaccination any time in the next 24 months will take a completely unprecedented feat of worldwide collaboration.
But I'm optimistic, the current situation has everyone focused on the issue. Except Trump trying to get some special deals for early access or whatever the fuck it is that he's doing.
Re: Covid-19 Vaccine Candidates
#24Question: if the virus completely dissapears in a few months, like other SARS variant, should we vaccinate the world population ?
We're well past the stage where the virus may 'disappear'. Look at MERS[0] (which is still around) and SARS[1]. Compare that to COVID-19 [2]. I'd say the case for vaccination is pretty obvious, even if there is a lull in cases. Seasonal COVID outbreaks don't sound fun. [0] https://upload.wikimedia.org/wikipedia/commons/thumb/7/7d/Wo... [1] https://upload.wikimedia.org/wikipedia/commons/thumb/e/e0/20... [2] https://up…
To be clear, MERS-CoV has not had sustained human-to-human transmission as of yet, rather repeated, smaller transmission pockets. Also, dromedary camels carry it and repeatedly introduce it into the human population.
Re: Covid-19 Vaccine Candidates
#25Earlier quoted context omitted.
Serious question, how could it disappear? It seems like as long as there are people close enough to infect, it will infect them. There are cases in warm environments. What am I missing?
Previous pandemics (most notably 1918 Spanish flu) have “disappeared” in the sense that they had either exhausted the pool of hosts and had no natural reservoir with which to fall back on or they mutated to become less deadly or less symptomatic.
The Spanish flu strain (H1N1) circulated as the common flu until 1957 when it was replaced by Asian flu in 1957 (H2N2). However, it reappeared briefly as the Russian flu in 1977.
Re: Covid-19 Vaccine Candidates
#26Has there ever been an attempt to develop a vaccine against SARS or MERS? If so, what happened? Did it fail or was is just not needed anymore?
From my understanding, they were started, but then both SARS and MERS burned out so fast that they couldn’t find enough candidates to test the vaccines by the time they got to trials.
Re: Covid-19 Vaccine Candidates
#27Has there ever been an attempt to develop a vaccine against SARS or MERS? If so, what happened? Did it fail or was is just not needed anymore?
That's how these got developed so fast, take a MERS vaccine and update it.
Click the wikipedia article, and click to the History section.
Re: Covid-19 Vaccine Candidates
#28Has there ever been an attempt to develop a vaccine against SARS or MERS? If so, what happened? Did it fail or was is just not needed anymore?
Wikipedia has a brief summary of prior work on vaccines against other coronaviruses, including SARS and MERS.
Re: Covid-19 Vaccine Candidates
#29Question: if the virus completely dissapears in a few months, like other SARS variant, should we vaccinate the world population ?
The SARS-1 outbreak lasted about two years. But if it _does_ vanish in a few months (sadly, this doesn't seem plausible), it would probably make sense to produce and stockpile a vaccine, if a viable one is found, but not actually vaccinate unless it reappears.
Did it realy last 2 years? This graphic indicates that it lasted only for 4 months, then is was more or less over:
https://en.wikipedia.org/wiki/Severe_acute_respiratory_syndr...
Re: Covid-19 Vaccine Candidates
#30Earlier quoted context omitted.
Serious question, how could it disappear? It seems like as long as there are people close enough to infect, it will infect them. There are cases in warm environments. What am I missing?
>What am I missing? delusion
Accepting that we know still very little about this pandemic and how it will play out is the only perspective that is not delusional.