> Deprivation was also found to be a major risk factor What does this mean? Sleep deprivation?
British term for poverty.
Goddamn British people. Why can’t they just speak English.
Factors associated with Covid-19 deaths in records of 17M adult NHS patients
31–40 of 204 posts
Re: Factors associated with Covid-19 deaths in records of 17M adult NHS patients
#32Earlier quoted context omitted.
It is not very useful to compare them with flu because people are much more likely to have flu than to have covid. These rates seem very small but remember that the study started in the beginning of february, when there were likely only a handful if any covid carriers in the uk. If you could preselect a group of people that you know had covid and measure their death rate, the numbers are likely to be much higher. Thi…
Also flu deaths have been greatly exaggerated. Which explains how with a supposed 50k flu deaths in a year in the USA, it has never inundated hospitals like this.
85k coronavirus deaths haven't inundated hospitals in the US either, except in the absolute epicenter in NYC, and even then not to the point originally feared. It's very easy to imagine 50k flu deaths geographically spread evenly not overwhelming US hospitals, especially given that they'd be spread over something like 3x the current coronavirus epidemic timespan. I'm very skeptical of the sudden "oh those flu deaths aren't real" narrative.
Re: Factors associated with Covid-19 deaths in records of 17M adult NHS patients
#33I think one of the key takeaways is in the abstract: > People from Asian and black groups are at markedly increased risk of in-hospital death from COVID-19, and contrary to some prior speculation is only partially attributable to pre-existing clinical risk factors or deprivation
>> is only partially attributable to pre-existing clinical risk factors or deprivation
I'd expect more it is attributable to less access to premium healthcare (remember, in the UK everyone gets healthcare, but not everyone gets privately-sponsored add-on healthcare)
Re: Factors associated with Covid-19 deaths in records of 17M adult NHS patients
#34I think one of the key takeaways is in the abstract: > People from Asian and black groups are at markedly increased risk of in-hospital death from COVID-19, and contrary to some prior speculation is only partially attributable to pre-existing clinical risk factors or deprivation
What does deprivation mean here? Early in the outbreak I remember seeing some research that indicated people of Asian descent (East Asian) are genetically predisposed to more severe cases of this coronavirus, something to do with higher expression of the ACE-2 receptor.
It means poor.
It's unclear to me (only skimmed the figures) if the various ethnic/racial hazard factors correct for poverty (deprivation) or not.
Re: Factors associated with Covid-19 deaths in records of 17M adult NHS patients
#35I think one of the key takeaways is in the abstract: > People from Asian and black groups are at markedly increased risk of in-hospital death from COVID-19, and contrary to some prior speculation is only partially attributable to pre-existing clinical risk factors or deprivation
It seems pretty remarkable that men have a hazard factor 2x that of women as well.
Re: Factors associated with Covid-19 deaths in records of 17M adult NHS patients
#36What is "Deprivation" in this context?
Poor. Many negative health outcomes correlate with poverty / deprivation.
Re: Factors associated with Covid-19 deaths in records of 17M adult NHS patients
#37Earlier quoted context omitted.
It is not very useful to compare them with flu because people are much more likely to have flu than to have covid. These rates seem very small but remember that the study started in the beginning of february, when there were likely only a handful if any covid carriers in the uk. If you could preselect a group of people that you know had covid and measure their death rate, the numbers are likely to be much higher. Thi…
Also flu deaths have been greatly exaggerated. Which explains how with a supposed 50k flu deaths in a year in the USA, it has never inundated hospitals like this.
Why do you think that 50k annual US flu deaths would be overwhelming the hospitals?
It would also be fantastic if you could provide a credible source for this surprising claim that US flu deaths are greatly overstated.
Re: Factors associated with Covid-19 deaths in records of 17M adult NHS patients
#38> Deprivation was also found to be a major risk factor What does this mean? Sleep deprivation?
Indices of Multiple Deprivation use a bunch of factors to measure how much it sucks to live somewhere. Other people are saying "poverty" but that's only part of the problem.
https://en.wikipedia.org/wiki/Multiple_deprivation_index
For example suppose you are very poor but you live where I grew up in Metroland. Lack of money sucks pretty badly, but in Metroland other deprivation factors are mostly low.
There are jobs in Metroland. The schools are pretty good. There's a hospital, and a nearby doctor with a friendly manner (remember Britain has universal healthcare, but universal does not mean universally excellent). You can't afford private rent here, but local government can find you somewhere to live, and not in six months but maybe six days.
The local crime isn't too bad. Vandals, maybe the odd burglary you suspect a neighbour is on the game (prostitution), but you don't fear for your life. The surrounding space is nice, there's a play park, rolling hills, fresh air if you like that sort of thing.
So in Metroland even the poor aren't very deprived.
In contrast, in some deprived Northern cities in particular, even the middle class suffer pretty badly, and will strive to get out.
Re: Factors associated with Covid-19 deaths in records of 17M adult NHS patients
#39I think one of the key takeaways is in the abstract: > People from Asian and black groups are at markedly increased risk of in-hospital death from COVID-19, and contrary to some prior speculation is only partially attributable to pre-existing clinical risk factors or deprivation
It seems pretty remarkable that men have a hazard factor 2x that of women as well.
There was a post on HN a few days ago about a study that found low testosterone levels were correlated with worse Covid-19 outcomes. I think vitamin D is technically a hormone (or maybe is hormone-like?) so I wonder if it’s absorbed differently by men than women. Or maybe low testosterone is just a side effect of a vitamin D deficiency in men.
Re: Factors associated with Covid-19 deaths in records of 17M adult NHS patients
#40Here's a link to the paper: https://www.medrxiv.org/content/10.1101/2020.05.06.20092999v... This is interesting data. I want to see Vitamin D status included in a large population study like this because I've been following two smaller studies covering about a thousand cases total that shows Vitamin D deficiency has a risk ratio of 10 to 20 (more even than being age 80+ in the above study). The studies: [1] https://p…
"98.9% of Vitamin D deficient cases died while only 1.1% of them were active cases. 87.8% of Vitamin D insufficient cases died while only 12.2% of them were active cases. Only 4.1% of cases with normal Vitamin D levels died while 95.9% of them were active cases."
Wait, only 13.3% (1.1 + 12.2) of all the active cases in total were vitamin D insufficient or worse? I thought the majority of people had insufficient vitamin D.
This data doesn't fully make sense to me. How come that so few people with a vitamin D insufficiency were active cases? I get that most of them died. But I don't get that so few, less than 15 percent, got to become an active case.
Edit: ah, it's an Indonesian study. Nevermind, I wouldn't know the numbers from there.