101–110 of 426 posts
Since it seems like the upshot of all of this is that Katcher is claiming to have discovered a set of signalling molecules which, when injected, rejuvenate tissue and presumably lengthen life, it runs into one of the most fundamental objections that can be leveled at theory of aging (or cure thereof): of the billions of humans that have existed, how is it that none of them have possessed a mutation which (in this cas…
Since it seems like the upshot of all of this is that Katcher is claiming to have discovered a set of signalling molecules which, when injected, rejuvenate tissue and presumably lengthen life, it runs into one of the most fundamental objections that can be leveled at theory of aging (or cure thereof): of the billions of humans that have existed, how is it that none of them have possessed a mutation which (in this cas…
At risk of sounding absolutely insane: There's probably no way to prove that this hasn't happened. Anyone who realizes they're not aging normally would likely have taken on a new identity elsewhere for fear of: 1. being burned at the stake 2. being trialed in repeated experiments 3. being deified, and then subsequently being burned at the stake. --- I realize my comment sounds like a joke, but I'm entirely serious. I…
Earlier quoted context omitted.
At risk of sounding absolutely insane: There's probably no way to prove that this hasn't happened. Anyone who realizes they're not aging normally would likely have taken on a new identity elsewhere for fear of: 1. being burned at the stake 2. being trialed in repeated experiments 3. being deified, and then subsequently being burned at the stake. --- I realize my comment sounds like a joke, but I'm entirely serious. I…
Might I recommend the "The Man from Earth" ( https://www.imdb.com/title/tt0756683/ ). Definitely worth checking out.
Since it seems like the upshot of all of this is that Katcher is claiming to have discovered a set of signalling molecules which, when injected, rejuvenate tissue and presumably lengthen life, it runs into one of the most fundamental objections that can be leveled at theory of aging (or cure thereof): of the billions of humans that have existed, how is it that none of them have possessed a mutation which (in this cas…
At risk of sounding absolutely insane: There's probably no way to prove that this hasn't happened. Anyone who realizes they're not aging normally would likely have taken on a new identity elsewhere for fear of: 1. being burned at the stake 2. being trialed in repeated experiments 3. being deified, and then subsequently being burned at the stake. --- I realize my comment sounds like a joke, but I'm entirely serious. I…
Since it seems like the upshot of all of this is that Katcher is claiming to have discovered a set of signalling molecules which, when injected, rejuvenate tissue and presumably lengthen life, it runs into one of the most fundamental objections that can be leveled at theory of aging (or cure thereof): of the billions of humans that have existed, how is it that none of them have possessed a mutation which (in this cas…
At risk of sounding absolutely insane: There's probably no way to prove that this hasn't happened. Anyone who realizes they're not aging normally would likely have taken on a new identity elsewhere for fear of: 1. being burned at the stake 2. being trialed in repeated experiments 3. being deified, and then subsequently being burned at the stake. --- I realize my comment sounds like a joke, but I'm entirely serious. I…
When the team went on an offsite morale event jet skiing, he was told by the proprietor that he couldn't participate because their policy requires you to be at least 16 years old. He was 27 at the time. He never lived that down with his peers. When he tries to go to a bar with friends, he's sometimes accused of trying to pass off a fake ID. These experiences are deeply embarrassing for him.
Imagine trying to get promoted to a senior director position at a company while looking like you are fresh out of college. In that case ageism takes a different meaning.
Nevertheless, there are significant conflicts of interest going on, so confirmatory studies by independent bodies in animal models are required. Then there are the human studies. They obviously want to use the epigenetic clock as a surrogate endpoint in humans, so the trial can be completed in a short time frame. Not sure about that, this is a fairly complicated surrogate endpoint we are talking about. Some more relevant biomarkers of aging in humans which incorporate functional readouts would be required at the very least.
https://www.biorxiv.org/content/10.1101/2020.05.07.082917v1....
Since it seems like the upshot of all of this is that Katcher is claiming to have discovered a set of signalling molecules which, when injected, rejuvenate tissue and presumably lengthen life, it runs into one of the most fundamental objections that can be leveled at theory of aging (or cure thereof): of the billions of humans that have existed, how is it that none of them have possessed a mutation which (in this cas…
Since it seems like the upshot of all of this is that Katcher is claiming to have discovered a set of signalling molecules which, when injected, rejuvenate tissue and presumably lengthen life, it runs into one of the most fundamental objections that can be leveled at theory of aging (or cure thereof): of the billions of humans that have existed, how is it that none of them have possessed a mutation which (in this cas…
Since it seems like the upshot of all of this is that Katcher is claiming to have discovered a set of signalling molecules which, when injected, rejuvenate tissue and presumably lengthen life, it runs into one of the most fundamental objections that can be leveled at theory of aging (or cure thereof): of the billions of humans that have existed, how is it that none of them have possessed a mutation which (in this cas…
People who had this mutation could have died of causes other than aging.
Earlier quoted context omitted.
To be clear: I do not see this as good news. The only way new life and new ideas arise is in the wake of the deceased. Death is neccessary for life. If those at the top can further cement and accumulate their wealth and power due to living longer lives, this is bad for everyone else.
Maybe not: the only way we're actually going to realistically colonize space as a species is if people live so long that a few hundred years in a spaceship is a reasonable sacrifice. I would imagine that the same people who were willing to spend fortunes on rejuvenation would also be willing to spend fortunes exploring new galaxies.