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Proton pump inhibitors (heartburn meds) linked with increased risk of dementia

alz-journals.onlinelibrary.wiley.com

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Re: Proton pump inhibitors (heartburn meds) linked with increased risk of dementia

#41
post #39
post #33

Earlier quoted context omitted.

I don't get why high fat foods are lumped in here. I've started avoiding all the others you mentioned, and my reflux has stopped, but I'm on a ketogenic diet that's very high in fat.

Some foods loosen the sphincter making it easier to get reflux. Like eating a slice of pepperoni pizza. My dietitian said each individual is different so you need to determine what works or doesn't works for you.

I think the most effective dietary advice in the world is this:

Change one thing for two weeks, and see if it gets better or worse.

You can fix a surprisingly wide range of problems by changing your diet in a slow, methodical way.

Re: Proton pump inhibitors (heartburn meds) linked with increased risk of dementia

#42
post #2

From abstract: "Given that accumulating evidence points at cholinergic dysfunction as a driving force of major dementia disorders, our findings mechanistically explain how prolonged use of PPIs may increase incidence of dementia. This call for restrictions for prolonged use of PPIs in elderly, and in patients with dementia or amyotrophic lateral sclerosis." This is classical A causes B and B causes C, so A leads to C…

> This is classical A causes B and B causes C, so A leads to C

Another one is salt intake raises blood pressure and high blood pressure causes heart attacks.

The reality is more complicated: https://www.thelancet.com/journals/lancet/article/PIIS0140-6...

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