The Dart VM is roughly based on V8's internals. Running dart alone would be similar to running node, which needs to initialize the VM, parse the code, and run it. This is obviously slower than a pre-compiled binary.
dart2native brings it half-way to native, by doing parsing and initialization, and saving a memory snapshot right before executing the main function. This greatly reduce startup time (and is the same technique that makes Flutter apps start fast), but still not as fast as a binary, since it is loading the snapshots and doing some initialization.
This is usually fast enough, because once the initialization is ran, the following code will run fast. This is a constant initialization loading time, and doesn't represent anything.
Saying 22ms doesn't mean anything, and feels like a misinformed statement.
Dart overall is a pleasant language, and it is somewhat unique that it provides multiple ways to run. You can run with dart, dart2native, dart2js, and I believe there's one for ARM (for Flutter). This allows you to choose the best for your target platform