Live data from Hacker News

Ask HN: What scientific phenomenon do you wish someone would explain better?

news.ycombinator.com

401–410 of 839 posts

Re: Ask HN: What scientific phenomenon do you wish someone would explain better?

#401
post #119

I would like to understand how cellular biology processes actually work. Like, how do all the right modules and proteins line up in the right orientation every time? Every time I watch animations, it seems like the proteins and such just magically appear when needed and disappear when not needed [0]. Sometimes it's an ultra-complex looking protein and it just magically flys over to the DNA, attaches to the correct sp…

I studied bioinformatics and found the standard textbook, Albert's "Molecular Biology of the Cell"[0] to be one of the most captivating books I've read. It's like those extremely detailed owners' manuals for early computers, except for cells. The amount of complexity is just absolutely insane. My favourite example: DNA is read in triplets. So, for example, "CAG" adds one Glutamine to the protein it's building[1]. The…

"The distance from brain to leg is too long, for example, to accurately control motion from "central command"

As a dancer, I have been fascinated by that fact. It means that dancers do not dance to the beat as they hear it - it takes too much time for the sound to be transformed by the ear/brain into an electrical pulse that reaches your leg. Instead, all dancers have a mental model of the music they dance to that is learnt by practice/repetition.

Dancing is just syncronizing that mental model to the actual rhythm that is heard. When I explained that to a bellydancer friend she finally understood the switch that she had made from being a beginning dancer to an experienced dancer who 'dances in their head'

Re: Ask HN: What scientific phenomenon do you wish someone would explain better?

#402

Lot's of quantum related phenomenon here, but what keeps bothering me is that while I get it that light is both a wave and a particle, but I have no clue what that means. I mean, a wave of sound, is made from air particles, a wave of ripples in a pond is made of movement of water molecules. In the double slit experiment, it's explained that the single photon has to be "interfering with itself", so I don't get it if b…

> while I get it that light is both a wave and a particle, but I have no clue what that means. Because it's wrong. It's a quantum of the electromagnetic field. It's neither a wave nor a particle. It just happens to have some properties of both.

I've done plenty of layman reading into QFT, and I'm truly good with this. All particles are really waves. There are no particles. There's self-interaction, and all other kinds of weird stuff. (it's important to qualify that stable orbits and molecules and stuff exist)

But for the duality, there's something bigger that the responses always seem to blow past. Is wave-like nature for explaining behavior (wavy double-slit intensity pattern), or is it something to have a mathematical mapping to measured probabilities?

Quantum stories always seem so backwards. The root phenomenon is some sort of irreducible probability. But then the mechanical part (inference in double-slit) goes a totally different direction. Instead of just turning the situation into a probability of one-or-the-other slit, it STAYS as a wave.

Okay, now you have a new hole in the story. If the photon refuses to choose just 1 slit to go through, why does it choose 1 spot on the photo paper to land on?

Why do we not still have to consider interference in outcomes after the photon makes its mark on the paper? Why does there appear to be like a limit on entanglement, such that it goes away beyond a certain scale? Why are quantum computers hard?

Re: Ask HN: What scientific phenomenon do you wish someone would explain better?

#403

The Oberth Effect. I’ve seen a bunch of awful attempts at the “why” and some “well it’s just in the math, so there” but nothing satisfying.

I answered this here: https://physics.stackexchange.com/questions/287101/where-doe...

The basic answer is that the extra energy that goes to the rocket comes from harvesting the kinetic energy that the fuel itself had by virtue of being in the moving rocket.

Re: Ask HN: What scientific phenomenon do you wish someone would explain better?

#404

Has someone that thought they were taking LSD ever turned into a permanent schizophrenic zombie or in a mental institution, or is it all urban legend. If someone that didn't know they were predisposed to mental illness, is it applicable to dismiss their experience in order to maintain how safe LSD is? If any of this is true, are there any sources aside from "my friend's friend's brother took too much and now he is...…

The answer to this is really easy. Go to any mental institution and get to know the patients. An institution where they are allowed out, but are still in an enclosed area. A majority of the patients will have had some sort of heavy drug use in their past. Sure, whats causation and whats correlation, but its pretty clear that drugs cause mental breaks. How do I know this? I have mental illness in my family and have sp…

That's unfortunate. Yes, I think it is clear too, but to so many it isn't that I have to figure out where is the truth? What circumstances cause what? Is it worthwhile to really avoid all psychonauts given the path they are on? For the ones with positive experiences on the total other side of the spectrum that take them into the spiritual mumbo jumbo, is this worth listening to? Is there a functional difference between the path the microdosers are taking and the ones that use 1000ug occassionally (ie. after smart people's 2.5 year stint at Google are they all on the path to a mental hospital?)

So many questions.

Where is the medical journal that says your conclusion "vast majority of mental health patients have a self-reported history of drug use of these specific drugs". I guess it can't exist because its crazy people self reporting a variety of substances that even the user would have no idea what was actually given to them.

Re: Ask HN: What scientific phenomenon do you wish someone would explain better?

#405

Hawking Radiation. I know just enough to know that the story of "anti-particle of virtual pairs happens to always fall in the hole" is a Lie Told To Children, but the explanations seem to go straight from there to rather dense math and I've never wrapped my head around it.

I hope this helps: https://www.youtube.com/watch?v=qPKj0YnKANw

Actually... yes, which just makes it worse that something about that presenter's style really rubs me the wrong way. Do they have their content in text format somewhere? Anyway, thanks!

Re: Ask HN: What scientific phenomenon do you wish someone would explain better?

#406

If I buy a stock, does the price at which I agreed to buy it become the new share price on the stock exchange? Every article on "Where do stock prices come from?" seems to just talk at a high level about supply and demand. But where does the price come from at a nitty-gritty level? Is it an average of all existing offers or something? Do different exchanges and stock-ticker websites have different formula for calcula…

To understand this, you should start by understanding the limit order book, which will give you a concrete model with which you can visualize the supply and demand.

In simple terms, when you want to buy 100 shares of a stock at no more than $4, you place a limit order into the exchange’s order book for that stock. Other buyers do the same, as do sellers. The order book is a sorted structure with the orders and their sizes on each side. It may look like this:

Sell 100 @ $7

Sell 300 @ $6

Sell 300 @ $5

Buy 100 @ $4 (your order)

Buy 200 @ $3

Buy 100 @ $2

Notice the gap between the highest buy (“bid”) and the lowest sell (“offer“ or “ask”). This is called the ”bid/ask spread.” Whether we’re talking stocks or eBay or a local outdoor market, buyers always want to pay less, sellers always want to earn more, and there is always a bid/ask spread.

If instead of sticking to your $4 limit, you said “forget it, I just want the stock” you would enter a market order instead of a limit order. In doing so you’d “cross the spread” and pay $5 per share. For a trade to happen, someone has to cross the spread.

If you entered a buy order with a limit of $100 in this example, you’d still buy at $5. If you ordered 400 shares at $100, you’d buy 300 at $5 and 100 at $6. The $5 offer would come out of the order book and the $6 offer would be reduced in size.

When you think of the market as all of this upward and downward price pressure focusing around a spread, you can see that the price the market values the stock at is conceptually the midpoint between the highest bid and the lowest offer, also known as the “mid.”

As prices change, the spread’s price level moves up and down, it narrows and widens, but the price you see always at least indirectly reflects that midpoint of price interest between all buyers and all sellers. There will always be intricacies in price reporting (based on the price feed, the price you see is the last trade made, the mid, or something more complex), but if you understand the order book, you’ll have the basic idea and can build from there.

If you’re really interested, you can google how and when the various exchanges calculate and report their prices, who they make them available to directly, what vendors provide raw and aggregate views of those prices, and more. There are many flavors varying from real-time tick-by-tick reporting to end of day feeds and more.

All of them ultimately begin with what you can now visualize as an order book.

Re: Ask HN: What scientific phenomenon do you wish someone would explain better?

#408
post #387

Why is it that the smartest people in various fields constantly need reference materials, but medical doctors never look anything up?

I've read that med school is really heavy on memorization.

Cynical answer: the culture of medicine was set during a 2000+-year period when physicians harmed more than helped; the way they made a living was by appearing authoritative.

Re: Ask HN: What scientific phenomenon do you wish someone would explain better?

#409

Earlier quoted context omitted.

just once i would like to see the realistic animation though even if it's impossible to understand

It would be pretty boring, proteins bouncing around randomly and occasionally honking up, substrates flying around like rifle bullets sometimes hitting the target, and everything smooshing around in random directions. If you’ve seen Brownian motion, you’ve seen what is happening to all the molecules but at 1/100 the length scale. Nothing stays put. Everything is moving fast and far on the scale of proteins and small…

Fast, yes. Far, well, the mean free path in a cell is very short.

Re: Ask HN: What scientific phenomenon do you wish someone would explain better?

#410

If I buy a stock, does the price at which I agreed to buy it become the new share price on the stock exchange? Every article on "Where do stock prices come from?" seems to just talk at a high level about supply and demand. But where does the price come from at a nitty-gritty level? Is it an average of all existing offers or something? Do different exchanges and stock-ticker websites have different formula for calcula…

Disclaimer: I used to work in HFT

Each exchange is basically its own world, with the exception of Reg NMS, which I'll get to in a sec.

Let's task about order books. Each stock has its own order book. This might be an example of the book for AAPL:

* SELLING 100 shares @ $10.02 * SELLING 200 shares @ $10.01 * SELLING 100 shares @ $10.00 * BUYING 100 shares @ $9.99 * BUYING 200 shares @ $9.98 * BUYING 100 shares @ $9.97

So if you want to buy some AAPL, you will want to go grab the cheapest shares you can see, which here is the fellow selling 100 shares at $10.00. You submit a limit order to buy at 10.00 and are matched with that guy. The book now looks like this:

* SELLING 100 shares @ $10.02 * SELLING 200 shares @ $10.01 * BUYING 100 shares @ $9.99 * BUYING 200 shares @ $9.98 * BUYING 100 shares @ $9.97

Now let's suppose a market maker decides they think the price is going to follow, so they go and fill in the hole by submitting an order to BUY 100 shares at 10.00. There's no more shares to buy at $10.00, so their order rests on the book.

Now we have:

* SELLING 100 shares @ $10.02 * SELLING 200 shares @ $10.01 * SELLING 100 shares @ $10.00 * BUYING 100 shares @ $10.00 * BUYING 100 shares @ $9.99 * BUYING 200 shares @ $9.98 * BUYING 100 shares @ $9.97

Now that we've played out this scenario, let's go back to your original question. What is the price of AAPL at any point in here? Well, it depends. At the start, if you wanted to buy, you could say the price is $10.00. But if you wanted to sell, the best you'd get is 9.99. So, hard to say.

It's worth noting that the prices you see in the book are only there because people aren't agreeing on the prices. If they did agree, a trade would happen, and the prices wouldn't be on the book. So, with that in mind, you could say that really, the price of a stock is the last price people agreed at: the last trade price. That's better, we're at least down to just one price to think about.

That could be quite different from what the best bid/offer are right now, though (some stocks don't trade very often) so even if (let's say) you last saw AAPL trade at 9.50 before our example, obviously that price is long gone. So even the last trade price is potentially not "the price of the stock".

So, in short, there's really no such thing as "the price of a stock". It'll all depend on how sophisticated you want to be about the price at which you buy your shares.

When people talk generally about the price of a stock, it's usually just up to whatever site people are looking at, and usually markets are liquid enough and trade enough that all the kinds of prices we just talked about are usually only a penny different, so when people are just at the watercooler saying "Did you see the price of AAPL?" they don't care about the pennies, and by the time they've managed to say that question, the price has moved anyway, probably lots of times. So it all gets a little hand-wave-y.

I want to mention two other things that might interest you. Reg NMS is what ties all the exchanges together, so to speak. Let's say you want to buy AAPL and NYSE has shares selling at $10.00 each, but NASDAQ has them for $9.99 each. It's actually illegal (against Reg NMS) to trade with that guy at $10.00 at NYSE because NASDAQ has the "NBBO" (national best bid/offer) right now. Extra caveat: if you sent a special order to NYSE that says "I promise you, I've also sent an order to NASDAQ to buy the shares for $9.99 and I've determined you're the next best price at $10.00, let me buy them", it'll let you. It's called an ISO (Intermarket Sweep Order) and if you lie about them or mistakenly lie about them, you get fined. A lot.

The other interesting thing: Your last question was "If a very low-volume stock is listed at $4, and then I offer to buy a share for $100, does the NYSE suddenly start listing its price at $100?" There's actually a lot to unpack here. Let's go through it.

If you're a registered broker-dealer and are connected directly to NYSE, and you send a limit order for XYZ @ $100/share, what's going to happen is you're going to get "price improvement" and you'll end up getting the shares at $4. If you send an order for LOTS of shares at $100, you'll clear out a bunch of price levels in one go. Ex:

Let's say this is the book for XYZ:

* [...] * SELLING 200 shares @ $110.00 * SELLING 1000 shares @ $5.00 * SELLING 200 shares @ $4.02 * SELLING 100 shares @ $4.01 * SELLING 500 shares @ $4.00 * BUYING 100 shares @ $3.99 * [...]

Usually when you get away from the middle of the book, liquidity dries up fast and the prices get further apart. So let's say you send an order for 10000 shares at $100. You're going to get 500 at $4, 100 at $4.01, 200 at $4.02, 1000 at $5.00. Now the next price is 110, but your limit price is 100. So your order will now actually rest partially-filled on the book. So now this is the book:

* [...] * SELLING 200 shares @ $110.00 * BUYING 8200 shares @ $100.00 * BUYING 100 shares @ $3.99 * [...]

Neat, huh? That was a lot of price movement. So yes, if you can send for enough shares and are willing to pay through a lot of price levels, you can move the price of the stock. Remember Reg NMS though - if more stock exchanges existed in our example, you'd also likely need to go get shares at them if they have a better price than the exchange you just moved the price at.

But let's now suppose you're NOT a registered broker-dealer, but are instead Joe A. Schmoe, a client of Charles Schwab Brokerage. You enter your order in your web browser and hit trade. Schwab has a legal obligation to fill your order, if possible, only at the NBBO. They could route your order right to an exchange, but instead, they will send your order to their friend, Citadel, who will have the opportunity to trade against your flow before it gets routed to the stock exchanges. Generally, this is good for you: they might decide your order represents good information and they want your shares. They could decide to fill your order themselves and sell you all 10000 shares you want. They're constrained by the NBBO though, so you get all 10000 shares at $4. For being the source of this order, Citadel pays Schwab some money. Usually practically a pittance, pennies, if that. Order flow is dirt cheap nowadays.

This is called "selling order flow" and lots of people find it scary, because it's not really super intuitive why someone would want to buy or sell the actual flow of orders. But it's actually pretty boring and more about high-level statistics than anything actually interesting to Joe Schmoe, who would get bored when he realized he's not really getting ripped off.

Sorry, I got a bit off-topic. But I love finance, so please forgive me.

Post reply on HN