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In 4 US state prisons, 3,300 inmates test positive, 96% without symptoms

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Re: In 4 US state prisons, 3,300 inmates test positive, 96% without symptoms

#161
post #42

I'd guess smoking rates are very high in prisons. It seems smokers (even former) are much better off than non-smokers.

Smoking weakens your heart and lungs (and probably doesn't help high blood pressure) so what makes you say that?

https://www.theguardian.com/world/2020/apr/22/french-study-s...

https://www.qeios.com/read/article/571

Re: In 4 US state prisons, 3,300 inmates test positive, 96% without symptoms

#162
post #58

Earlier quoted context omitted.

Not sure why you are being downvoted: https://www.oxfordbiosystems.com/COVID-19-Rapid-test "In order to test the detection sensitivity and specificity of the COVID-19 IgG-IgM combined antibody test, blood samples were collected from COVID-19 patients from multiple hospitals and Chinese CDC laboratories. The tests were done separately at each site. A total of 525 cases were tested: 397 (positive) clinically confirmed…

I wonder what's the process through which false positives happen in this case. Previous infection by milder Coronaviruses? Edit: I'm looking at the reddit post but I have a lot of reservations with the "prevalence 0.06", unless we'll use the test to test absolutely everybody and not only people who are suspect. Has that calculator been validated as well? If the test was 12 false positives in 128 negatives, how come t…

Apologies for the way this was linked to. The 6% is from this study:

https://www.miamidade.gov/releases/2020-04-24-sample-testing...

"Our data from this week and last tell a very similar story. In both weeks, 6% of participants tested positive for COVID-19 antibodies, which equates to 165,000 Miami-Dade County residents"

That is what the commentator is referring to in the linked post.

So if you plug their own figures into the calculator:

Sensitivity .8866 Specificity .9063

and a Prevalence of .06 based on the study, you get the 62% false positive rate.

As the prevalence increases, as with the NYC study which found the positive rate to be 21% (prevalence), the false positive rate decreases, down to 28% of the NYC study.

Re: In 4 US state prisons, 3,300 inmates test positive, 96% without symptoms

#163
post #58

Earlier quoted context omitted.

Not sure why you are being downvoted: https://www.oxfordbiosystems.com/COVID-19-Rapid-test "In order to test the detection sensitivity and specificity of the COVID-19 IgG-IgM combined antibody test, blood samples were collected from COVID-19 patients from multiple hospitals and Chinese CDC laboratories. The tests were done separately at each site. A total of 525 cases were tested: 397 (positive) clinically confirmed…

I wonder what's the process through which false positives happen in this case. Previous infection by milder Coronaviruses? Edit: I'm looking at the reddit post but I have a lot of reservations with the "prevalence 0.06", unless we'll use the test to test absolutely everybody and not only people who are suspect. Has that calculator been validated as well? If the test was 12 false positives in 128 negatives, how come t…

[deleted]

Re: In 4 US state prisons, 3,300 inmates test positive, 96% without symptoms

#164

Earlier quoted context omitted.

Ultimately this has exposed that WHO is a malicious institution which actively undermines the public health for Tedros Adhanom's personal relationship to the cause of the CCP and of fascism more generally. Each of our government's dangerously false statements has come from the WHO, and trusting them has been the primary mistake made in assessing this threat. "no evidence of Human-to-human spread" when they had eviden…

I can’t believe this is not a new account. Blanket propagandistic statements are not the conversation we have in Hacker News comments.

>Blanket propagandistic statements

Blanket implies "all". Are the OP's following statements incorrect?:

"no evidence of Human-to-human spread" when they had evidence, "no evidence of asymptomatic spread" when we all had evidence, "no evidence of aerosol spread" when there was evidence in public view

Taiwan warned the WHO with respect to human-to-human transmission. Is this in dispute?

https://www3.nhk.or.jp/nhkworld/en/news/20200412_01/

>not the conversation we have in Hacker News comments.

These are precisely the sorts of conversations people should be having.

Re: In 4 US state prisons, 3,300 inmates test positive, 96% without symptoms

#165
post #14

Before the deluge of "But wait two weeks" comments, I just want to ask at what point we accept that the potentially of totally asymptomatic cases is insanely high, far higher than anyone thought?

There's also the nuance of US state prison care quality. "Without symptoms" could just mean "not obviously gasping for air" .

Amnesty International campaign against this and are currently calling for the release of ICE detainees. Judging by a skim of their releases even those obviously gasping for air don’t necessarily get the care they need. It’s a truely massive system which in itself is part of the problem, though the exceptionally low bar for the care of prisoners is Amnesty’s primary angle.

https://www.amnesty.org/en/latest/news/2020/04/usa-covid19-p...

Re: In 4 US state prisons, 3,300 inmates test positive, 96% without symptoms

#166
post #55

As a Canadian, I'm shaking my head at our officials who said "we do know that asymptomatic people are not the key driver of epidemics" as a response to concerns back in January of the potential for the virus to grow in our country via incoming travelers who came from hot spots and were not screened or forced to isolate if they expressed no symptoms. Now our long term care facilities are being overrun with cases poten…

Agreed 100%. Here in BC, public health wasn't even saying, "It's not known whether asymptomatic carriers can spread the virus," but actually, "Evidence suggests asymptomatic carriers can not spread the virus." Something that as far as I can tell was never actually true. This was reported in public briefings, was repeated by public health nurses on the call-in lines, and was distributed as the government's official po…

Exactly like in Sweden. Our ministry of health has _almost_ given up the claim that asymptomatic carriers don't spread the virus by now, so... Progress!

Re: In 4 US state prisons, 3,300 inmates test positive, 96% without symptoms

#167
post #142

Earlier quoted context omitted.

I actually do remember reading that this was true specifically in the case of COVID — that more exposure so far seems to correlate with a worse infection. Sadly, I have no idea where I read this. But... I know I did! Recently! Maybe NYT?

Yeah, I saw it too. The hypothesis, as I recall, is that the more virions inhaled, the more likely some of them will get deep in the lungs where they can do the most damage.

I read something like that too. I came away thinking that ingestion might be a better way to get it than inhalation. I think you really need to keep it out of the lungs and nervous system. But that's all my impression from who knows where.

Re: In 4 US state prisons, 3,300 inmates test positive, 96% without symptoms

#168
post #52

I've read that asymptomatic carriers are though to be less infectious than those with symptoms because of the lower concentration of virus in the saliva. Also, many virologists mentioned in recent texts that the initial concentration of the virus you receive can affect how sick you'll get - the more viruses you're exposed to, the faster they can invade the body and the more severe it will get. Can those two facts be…

Where did you read that? Superficially that might make sense - less virus particles == less obvious symptoms - but there are a wide variety of virus responses that show virulence and infectiousness aren't necessarily correlated. If anyone wants to read more about this I can't recommend highly enough the book Spillover by David Quammen, which was published in 2012, and covers zoonotic (animal-to-human transmission) vi…

https://www.newscientist.com/article/2238819-does-a-high-vir...

Re: In 4 US state prisons, 3,300 inmates test positive, 96% without symptoms

#169
post #153

96% are without symptoms yet . There was a nursing home in Massachusetts which had 51 out of 98 residents testing positive but asymptomatic in early April. While this sounded encouraging in the sense no one was critically ill because of coronavirus, a few weeks later 19 had died and about 30 more had tested positive. Let’s wait a month until there is a clearer picture about the impact of the virus on a particular pop…

Did you see the NYC antibody sample that showed that approximately 21 percent of citizens had antibodies? It seems like a nursing home is a pretty bad representation of a population.

Am I the only one who is still confused by what they're finding in these antibody tests? Are they looking for antibodies that attach to specific features unique to SARS-CoV-2? Because I'm pretty sure even HCoV-NL63 enter lung cells through ACE2 as well. How can they tell antibodies for these viruses apart? Also aren't antibodies effectively developed in a sort of random process?

Re: In 4 US state prisons, 3,300 inmates test positive, 96% without symptoms

#170
post #58

Earlier quoted context omitted.

Not sure why you are being downvoted: https://www.oxfordbiosystems.com/COVID-19-Rapid-test "In order to test the detection sensitivity and specificity of the COVID-19 IgG-IgM combined antibody test, blood samples were collected from COVID-19 patients from multiple hospitals and Chinese CDC laboratories. The tests were done separately at each site. A total of 525 cases were tested: 397 (positive) clinically confirmed…

I wonder what's the process through which false positives happen in this case. Previous infection by milder Coronaviruses? Edit: I'm looking at the reddit post but I have a lot of reservations with the "prevalence 0.06", unless we'll use the test to test absolutely everybody and not only people who are suspect. Has that calculator been validated as well? If the test was 12 false positives in 128 negatives, how come t…

Yes. That’s one possible explanation. Interestingly quite a lot of people might be somewhat immune to the new Corona virus due to anti bodies from previous Corona cold infections. More than 30% showed such antibodies in a recent study. https://www.finanzen.net/nachricht/aktien/drosten-hinweis-au... (Sorry that the only source I have ready right now)
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