It would make sense if smoking (the oxidants from smoke) kills the virus.
However, once the infection actually progresses it is clear that smokers are worse off.
https://chrismasterjohnphd.com/covid-19/covid-19-and-the-smo...
Low incidence of daily active tobacco smoking in patients with symptomatic C19
21–30 of 55 posts
Re: Low incidence of daily active tobacco smoking in patients with symptomatic C19
#22Interesting, they hypothesize that nicotine is responsible: > There are however, sufficient scientific data to suggest that smoking protection is likely to be mediated by nicotine. SARS-CoV2 is known to use the angiotensin converting enzyme 2 (ACE2) receptor for cell entry[14-16], and there is evidence that nicotine modulates ACE2 expression[17]which could in turn modulate the nicotinic acetyl choline receptor (manus…
So start taking nicotine lozenges as a prophylactic?
This might be a joke, but I'm "addicted" to nicotine gum (and don't otherwise smoke). I probably caught the virus early on, and it wasn't particularly bad for me (even compared to typical flu).
That's not even really a single data point, but I'm curious to see how this pans out.
Re: Low incidence of daily active tobacco smoking in patients with symptomatic C19
#23Hypothesis: if you have any pre-existing lung conditions, you are more likely to quit smoking. In other words, if you're the sort with pre-existing conditions that make you more likely to be hospitalized if you get Covid-19, then you would be more likely to have quit smoking (or died before now if you didn't). Still an interesting result, but not, needless to say, a reason to start smoking.
I find it interesting that smoking itself isn't a pre-existing condition that makes you more likely to be hospitalized if you get Covid-19.
It's important to be careful here: the finding above is with symptomatic covid, not hospitalization. We don't know whether or not it makes you more likely to be hospitalized.
Re: Low incidence of daily active tobacco smoking in patients with symptomatic C19
#24Re: Low incidence of daily active tobacco smoking in patients with symptomatic C19
#25Earlier quoted context omitted.
So start taking nicotine lozenges as a prophylactic?
Would orally ingested nicotine protect lungs the same way that inhaled nicotine does?
Its far to premature to even conclude that inhaled nicotine protects the lungs. This is just one study. Don't do anything stupid, like go develop a nicotine addiction, just because of one headline.
Re: Low incidence of daily active tobacco smoking in patients with symptomatic C19
#26Earlier quoted context omitted.
So start taking nicotine lozenges as a prophylactic?
This might be a joke, but I'm "addicted" to nicotine gum (and don't otherwise smoke). I probably caught the virus early on, and it wasn't particularly bad for me (even compared to typical flu). That's not even really a single data point, but I'm curious to see how this pans out.
> I probably caught the virus early on, and it wasn't particularly bad for me (even compared to typical flu).
Do you have reason to believe that, or were you sick in January/February and just kind of assume that was it, even though we were at the height of regular cold and flu season?
Re: Low incidence of daily active tobacco smoking in patients with symptomatic C19
#27Re: Low incidence of daily active tobacco smoking in patients with symptomatic C19
#28Interesting, they hypothesize that nicotine is responsible: > There are however, sufficient scientific data to suggest that smoking protection is likely to be mediated by nicotine. SARS-CoV2 is known to use the angiotensin converting enzyme 2 (ACE2) receptor for cell entry[14-16], and there is evidence that nicotine modulates ACE2 expression[17]which could in turn modulate the nicotinic acetyl choline receptor (manus…
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Re: Low incidence of daily active tobacco smoking in patients with symptomatic C19
#29Earlier quoted context omitted.
I find it interesting that smoking itself isn't a pre-existing condition that makes you more likely to be hospitalized if you get Covid-19.
engaging in a risk factor is not a condition.
Depends on what you mean as a "condition". In a medical record, smoking status is often stored as a top-level value tied directly to the patient, and also often coded into their condition list[0]. In the FHIR standard, a physician's observation of a patient's smoking history is usually represented with an observation resource, but often will be "upgraded" to a condition resource[1].
But, yeah, from a non-healthcare data standpoint, what a "condition" is really just depends on your definition.
[0] https://www.icd10data.com/ICD10CM/Codes/F01-F99/F10-F19/F17-...
Re: Low incidence of daily active tobacco smoking in patients with symptomatic C19
#30It would make sense if smoking (the oxidants from smoke) kills the virus. However, once the infection actually progresses it is clear that smokers are worse off. https://chrismasterjohnphd.com/covid-19/covid-19-and-the-smo...
Actually in the article there's a different proposed explanation related to nicotine and its withdraw when in an hospital setting.